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ChemicalBook >> CAS DataBase List >>Sevelamer carbonate

Sevelamer carbonate

CAS No.
845273-93-0
Chemical Name:
Sevelamer carbonate
Synonyms
Sevelam;Sevelam carbonate;Sevelamer carbonate;SEVELEMER CARBONATE;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
CBNumber:
CB32128754
Molecular Formula:
C7H14ClNO4
Molecular Weight:
211.64
MDL Number:
MFCD18904375
MOL File:
845273-93-0.mol
MSDS File:
SDS
Last updated:2026-01-13 11:17:52
Product description Number Pack Size Price
Sevelamer Carbonate, Technical Grade TRC-S039370-500MG 500mg $223
Sevelamer Carbonate, Technical Grade TRC-S039370-1G 1g $384
Sevelamer Carbonate, Technical Grade TRC-S039370-100MG 100mg $146
Sevelamer carbonate FS137481 0.025kg $288.24
Sevelamer carbonate FS137481 0.05kg $480.82
More product size

Sevelamer carbonate Properties

storage temp. Room Temperature, under inert atmosphere
solubility <4.74mg/mL in DMSO
form Solid
color White to Pale Beige
Major Application pharmaceutical (small molecule)
InChI InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4)
InChIKey PADGNZFOVSZIKZ-UHFFFAOYSA-N
SMILES C(O)(O)=O.C(C1OC1)Cl.C(=C)CN
FDA UNII 9YCX42I8IU
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Hazard statements  H412
Precautionary statements  P273-P501
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Sevelamer carbonate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-S039370-500MG Sevelamer Carbonate, Technical Grade 845273-93-0 500mg $223 2026-06-03 Buy
TRC TRC-S039370-1G Sevelamer Carbonate, Technical Grade 845273-93-0 1g $384 2026-06-03 Buy
TRC TRC-S039370-100MG Sevelamer Carbonate, Technical Grade 845273-93-0 100mg $146 2026-06-03 Buy
Biosynth FS137481 Sevelamer carbonate 845273-93-0 0.025kg $288.24 2026-06-04 Buy
Biosynth FS137481 Sevelamer carbonate 845273-93-0 0.05kg $480.82 2026-06-04 Buy
Product number Packaging Price Buy
TRC-S039370-500MG 500mg $223 Buy
TRC-S039370-1G 1g $384 Buy
TRC-S039370-100MG 100mg $146 Buy
FS137481 0.025kg $288.24 Buy
FS137481 0.05kg $480.82 Buy

Sevelamer carbonate Chemical Properties,Uses,Production

Description

Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.

Uses

Control of serum phosphorus in patients with chronic kidney disease (phosphate binder).

Uses

Sevelamer Carbonate, a non-absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-based phosphate binders.

Side effects

The Common Side Effects of Sevelamer carbonate:
Vomiting (22%), Nausea (20%), Diarrhea (19%), Indigestion (16%), Stomach pain (9%), Feeling gassy (8%), and Constipation (8%).
The Serious Side Effects of Sevelamer carbonate:
Stomach or intestine problems: bowel blockage, bleeding ulcers, severe stomach pain, blood in your stool.

Mode of action

The active substance in Sevelamer carbonate Winthrop, sevelamer carbonate, is a phosphate binder. When taken with meals, it attaches in the gut to phosphate from the food, thereby preventing the phosphate from being absorbed into the body and helping to reduce phosphate levels in the blood.

Sevelamer carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 236)Suppliers
Supplier Tel Email Country ProdList Advantage
Protheragen-ING
+16313385890 info@protheragen-ing.com United States 3868 58
airuikechemical co., ltd.
+86-18353166132 sales02@airuikechemical.com China 983 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6366 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460 faith@widelychemical.com CHINA 742 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58

View Lastest Price from Sevelamer carbonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sevelamer carbonate pictures 2026-05-22 Sevelamer carbonate
845273-93-0
1G/KG 99% 100000000KG Anhuyan (Hainan) Biotechnology Co., LTD
SevelaMer carbonate pictures 2026-05-15 SevelaMer carbonate
845273-93-0
$396.00 1Kg/Bag 98% 1000KG Baoji Guokang Healthchem Co., Ltd.
2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate  pictures 2025-11-18 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
845273-93-0
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate Sevelamer carbonate Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine Sevelam 2-Propen-1-amine polymer with (chloromethyl)oxiran 2-Propen-1-aminepolymerwith carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine SIM862 Sevelamer Carbonate-----25gm Sevelamer Carbonate, Technical Grade 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate ISO 9001:2015 REACH Sevelam carbonate SEVELEMER CARBONATE 845273-93-0 C3H7NmC3H5ClOnCH2O3x C3H7NC3H5ClOxxCH2O3 Inhibitors Pharmaceutical intermediate Other APIs
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