Sevelamer carbonate
- CAS No.
- 845273-93-0
- Chemical Name:
- Sevelamer carbonate
- Synonyms
- Sevelam;Sevelam carbonate;Sevelamer carbonate;SEVELEMER CARBONATE;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
- CBNumber:
- CB32128754
- Molecular Formula:
- C7H14ClNO4
- Molecular Weight:
- 211.64
- MDL Number:
- MFCD18904375
- MOL File:
- 845273-93-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Sevelamer Carbonate, Technical Grade | TRC-S039370-500MG | 500mg | $223 |
| Sevelamer Carbonate, Technical Grade | TRC-S039370-1G | 1g | $384 |
| Sevelamer Carbonate, Technical Grade | TRC-S039370-100MG | 100mg | $146 |
| Sevelamer carbonate | FS137481 | 0.025kg | $288.24 |
| Sevelamer carbonate | FS137481 | 0.05kg | $480.82 |
| More product size | |||
| storage temp. | Room Temperature, under inert atmosphere |
|---|---|
| solubility | <4.74mg/mL in DMSO |
| form | Solid |
| color | White to Pale Beige |
| Major Application | pharmaceutical (small molecule) |
| InChI | InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4) |
| InChIKey | PADGNZFOVSZIKZ-UHFFFAOYSA-N |
| SMILES | C(O)(O)=O.C(C1OC1)Cl.C(=C)CN |
| FDA UNII | 9YCX42I8IU |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
Sevelamer carbonate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-S039370-500MG | Sevelamer Carbonate, Technical Grade | 845273-93-0 | 500mg | $223 | 2026-06-03 | Buy |
| TRC | TRC-S039370-1G | Sevelamer Carbonate, Technical Grade | 845273-93-0 | 1g | $384 | 2026-06-03 | Buy |
| TRC | TRC-S039370-100MG | Sevelamer Carbonate, Technical Grade | 845273-93-0 | 100mg | $146 | 2026-06-03 | Buy |
| Biosynth | FS137481 | Sevelamer carbonate | 845273-93-0 | 0.025kg | $288.24 | 2026-06-04 | Buy |
| Biosynth | FS137481 | Sevelamer carbonate | 845273-93-0 | 0.05kg | $480.82 | 2026-06-04 | Buy |
Sevelamer carbonate Chemical Properties,Uses,Production
Description
Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.
Uses
Control of serum phosphorus in patients with chronic kidney disease (phosphate binder).
Uses
Sevelamer Carbonate, a non-absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-based phosphate binders.
Side effects
The Common Side Effects of Sevelamer carbonate:
Vomiting (22%), Nausea (20%), Diarrhea (19%), Indigestion (16%), Stomach pain (9%), Feeling gassy (8%), and Constipation (8%).
The Serious Side Effects of Sevelamer carbonate:
Stomach or intestine problems: bowel blockage, bleeding ulcers, severe stomach pain, blood in your stool.
Mode of action
The active substance in Sevelamer carbonate Winthrop, sevelamer carbonate, is a phosphate binder. When taken with meals, it attaches in the gut to phosphate from the food, thereby preventing the phosphate from being absorbed into the body and helping to reduce phosphate levels in the blood.
Sevelamer carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Protheragen-ING | +16313385890 | info@protheragen-ing.com | United States | 3868 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from Sevelamer carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-22 | Sevelamer carbonate
845273-93-0
|
1G/KG | 99% | 100000000KG | Anhuyan (Hainan) Biotechnology Co., LTD | ||
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2026-05-15 | SevelaMer carbonate
845273-93-0
|
$396.00 | 1Kg/Bag | 98% | 1000KG | Baoji Guokang Healthchem Co., Ltd. | |
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2025-11-18 | 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
845273-93-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-

- Sevelamer carbonate
845273-93-0
- $0.00
- 99%
- Anhuyan (Hainan) Biotechnology Co., LTD
-

- SevelaMer carbonate
845273-93-0
- $396.00
- 98%
- Baoji Guokang Healthchem Co., Ltd.
-

- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
845273-93-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
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