2-Chloro-3-fluoro-5-nitropyridine
- CAS No.
- 1079179-12-6
- Chemical Name:
- 2-Chloro-3-fluoro-5-nitropyridine
- Synonyms
- 2-Chloro-3-fluoro-5-nitropyridine;Pyridine, 2-chloro-3-fluoro-5-nitro-;2-Chloro-3-fluoro-5-nitropyridine ISO 9001：2015 REACH
- CBNumber:
- CB32490918
- Molecular Formula:
- C5H2ClFN2O2
- Molecular Weight:
- 176.53
- MDL Number:
- MFCD16659664
- MOL File:
- 1079179-12-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-3-fluoro-5-nitropyridine >98% | PC910735 | 250mg | $21 |
| 2-Chloro-3-fluoro-5-nitropyridine >98% | PC910735 | 1g | $22 |
| 2-Chloro-3-fluoro-5-nitropyridine >98% | PC910735 | 5g | $102 |
| 2-Chloro-3-fluoro-5-nitropyridine >98% | PC910735 | 25g | $502 |
| 2-Chloro-3-fluoro-5-nitropyridine >98% | PC910735 | 100g | $2005 |
| More product size | |||
| Boiling point | 247.0±35.0 °C(Predicted) |
|---|---|
| Density | 1.595±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | -4.41±0.10(Predicted) |
| Appearance | White to light yellow Solid |
| InChI | InChI=1S/C5H2ClFN2O2/c6-5-4(7)1-3(2-8-5)9(10)11/h1-2H |
| InChIKey | SHXURKRHCSAERA-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C([N+]([O-])=O)C=C1F |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
2-Chloro-3-fluoro-5-nitropyridine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC910735 | 2-Chloro-3-fluoro-5-nitropyridine >98% | 1079179-12-6 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC910735 | 2-Chloro-3-fluoro-5-nitropyridine >98% | 1079179-12-6 | 1g | $22 | 2026-06-04 | Buy |
| Apolloscientific | PC910735 | 2-Chloro-3-fluoro-5-nitropyridine >98% | 1079179-12-6 | 5g | $102 | 2026-06-04 | Buy |
| Apolloscientific | PC910735 | 2-Chloro-3-fluoro-5-nitropyridine >98% | 1079179-12-6 | 25g | $502 | 2026-06-04 | Buy |
| Apolloscientific | PC910735 | 2-Chloro-3-fluoro-5-nitropyridine >98% | 1079179-12-6 | 100g | $2005 | 2026-06-04 | Buy |
2-Chloro-3-fluoro-5-nitropyridine Chemical Properties,Uses,Production
Synthesis
1033202-14-0
1079179-12-6
General procedure for the synthesis of 2-chloro-3-fluoro-5-nitropyridine from 3-fluoro-5-nitropyridin-2(1H)-one: To a stirred solution of 3-fluoro-5-nitropyridin-2-ol (1.5 g, 9.48 mmol) in phosphorus trichloride (15 mL) was slowly added phosphorus pentachloride (2.96 g, 14.22 mmol) at 60 °C. The reaction mixture was kept continuously stirred at 60 °C for 10 hours. After the reaction was completed, the mixture was cooled to room temperature and carefully poured into crushed ice. Extraction was carried out with ethyl acetate (3 x 20 mL). The organic layers were combined and washed with saturated sodium carbonate solution (25 mL) and subsequently dried over anhydrous magnesium sulfate. The organic layer was concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by silica gel column chromatography (100-200 mesh, eluent 5% ethyl acetate in hexane solution) to afford the target compound 2-chloro-3-fluoro-5-nitropyridine (1.62 g, 97% yield).
References
[1] Patent: WO2013/13817, 2013, A1. Location in patent: Page/Page column 96; 97
[2] Patent: WO2013/13815, 2013, A1. Location in patent: Page/Page column 131
[3] Patent: US2013/29961, 2013, A1. Location in patent: Paragraph 0656
[4] Patent: US2013/29962, 2013, A1. Location in patent: Paragraph 0761
[5] MedChemComm, 2016, vol. 7, # 5, p. 1022 - 1032
2-Chloro-3-fluoro-5-nitropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Allfluoro pharmaceutical co. ltd. | +86-400-0216110 +86-15958047586 | sales@allfluoro.com | China | 11380 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9631 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23506 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
View Lastest Price from 2-Chloro-3-fluoro-5-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 2-Chloro-3-fluoro-5-nitropyridine
1079179-12-6
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-01-03 | 2-Chloro-3-fluoro-5-nitropyridine
1079179-12-6
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-Chloro-3-fluoro-5-nitropyridine
1079179-12-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Chloro-3-fluoro-5-nitropyridine
1079179-12-6
- $1.00
- 99%
- Career Henan Chemical Co
