Albendazole S-oxide
- CAS No.
- 54029-12-8
- Chemical Name:
- Albendazole S-oxide
- Synonyms
- RICOBENDAZOLE;ALBENDAZOLE SULFOXIDE;ALBENDAZOLE OXIDE;Albendazole sulphoxide;RicobendazoL;RS-8852;Rycobendzole;RECOBENDAZOLE;RICOBENDAZOLEC;albendazole s-oxide
- CBNumber:
- CB3319817
- Molecular Formula:
- C12H15N3O3S
- Molecular Weight:
- 281.33
- MDL Number:
- MFCD00797922
- MOL File:
- 54029-12-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Albendazole sulfoxide ≥97% (HPLC) | SMB01325 | 100MG | $142 |
| Albendazole sulfoxide VETRANAL | 35395 | 10mg | $322 |
| Albendazole Sulfoxide | A3316 | 5G | $21 |
| Albendazole Sulfoxide | A3316 | 25G | $60 |
| Ricobendazole ≥98% | 21880 | 5g | $49 |
| More product size | |||
| Melting point | 226-228°C dec. |
|---|---|
| Density | 1.40 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly, Heated), Methanol (Slightly) |
| form | Solid |
| pka | pKa 3.28±0.01(H2O t=25.0±0.1 I=0.1(NaCl))(Approximate); 9.93±0.01(H2O t=25.0±0.1 I=0.1(NaCl))(Approximate) |
| color | colorless or white |
| Water Solubility | 62mg/L(25 ºC) |
| BRN | 677664 |
| Major Application |
forensics and toxicology pharmaceutical (small molecule) |
| InChI | 1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) |
| InChIKey | VXTGHWHFYNYFFV-UHFFFAOYSA-N |
| SMILES | CCCS(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1 |
| CAS DataBase Reference | 54029-12-8(CAS DataBase Reference) |
| FDA UNII | J39B52TV34 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H361d-H373-H410 | |||||||||
| Precautionary statements | P201-P202-P273-P280-P302+P352-P308+P313 | |||||||||
| target organs | Adrenal gland,spleen,male reproductive organs,Blood | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FD1080000 | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Repr. 2 Skin Sens. 1 STOT RE 2 Oral |
|||||||||
| NFPA 704 |
|
Albendazole S-oxide price More Price(89)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB01325 | Albendazole sulfoxide ≥97% (HPLC) | 54029-12-8 | 100MG | $142 | 2026-04-30 | Buy |
| Sigma-Aldrich | 35395 | Albendazole sulfoxide VETRANAL | 54029-12-8 | 10mg | $322 | 2026-04-30 | Buy |
| TCI Chemical | A3316 | Albendazole Sulfoxide | 54029-12-8 | 5G | $21 | 2026-04-30 | Buy |
| TCI Chemical | A3316 | Albendazole Sulfoxide | 54029-12-8 | 25G | $60 | 2026-04-30 | Buy |
| Cayman Chemical | 21880 | Ricobendazole ≥98% | 54029-12-8 | 5g | $49 | 2026-04-30 | Buy |
Albendazole S-oxide Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Powder
Uses
Tubulin polymerization or assembled inhibitors
Uses
A metabolite of Albendazole, an anthelmintic
Definition
ChEBI: Albendazole S-oxide is a sulfoxide. It is functionally related to an albendazole.
Biological Activity
Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.
Synthesis
34840-23-8
66868-66-4
54029-12-8
3.56 g (18 mmol) of 4-(1-propylsulfinyl)-1,2-diaminobenzene was dissolved in 45 mL of methanol and 1.03 mL of acetic acid and 3.84 g (19.8 mmol) of 1,3-bis(methoxycarbonyl)-S-methylisothiourea were added. The reaction mixture was heated to reflux for 2.5 hours, followed by cooling and removing the solvent under reduced pressure. The resulting white solid was digested with water, filtered, washed with ether and dried to give 4.1 g of white solid product, albendazole sulfoxide, with a melting point of 205°C to 216°C and a yield of 81%.
in vivo
Albendazole sulfoxide (0.5 mg/kg, i.m., BID, 15 days) reduces cyst size and weight in Balb/c mice infected with protoscoleces[3].
References
[1] Patent: US4076825, 1978, A
Albendazole S-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Hebei ZB Gamay Biological Technology Co.,Ltd | +8617330018573 | info@zbvet.net | China | 263 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
View Lastest Price from Albendazole S-oxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-02 | Albendazole sulfoxide
54029-12-8
|
$40.00 | 98.04% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-10 | Albendazole S-oxide
54029-12-8
|
$2.00-5.00 | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. | |
 |
2025-11-18 | Albendazole S-oxide USP/EP/BP
54029-12-8
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Albendazole sulfoxide
54029-12-8
- $40.00
- 98.04%
- TargetMol Chemicals Inc.
-
- Albendazole S-oxide
54029-12-8
- $2.00-5.00
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
-
- Albendazole S-oxide USP/EP/BP
54029-12-8
- $1.10
- 99.9%
- Dideu Industries Group Limited
