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ChemicalBook >> CAS DataBase List >>3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE

3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE

CAS No.
552-54-5
Chemical Name:
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
Synonyms
RhaMnacine;3,7-DIMETHYLQUERCETIN;C.I.75700;rhamnacene;NSC 678106;RHAMNAZIN(SH);7,3'-DiMethylquercetin;7,3'-Di-O-methylquercetin;3',7-Di-O-Methylquercetin;QUERCETIN-3,7-DIMETHYL ETHER
CBNumber:
CB3409525
Molecular Formula:
C17H14O7
Molecular Weight:
330.29
MDL Number:
MFCD00017426
MOL File:
552-54-5.mol
MSDS File:
SDS
Last updated:2026-01-13 11:20:23
Product description Number Pack Size Price
Rhamnazin ≥99% (HPLC) 93815 5mg $484
3,7-Dimethoxy-3',4',5-Trihydroxyflavone FD22462 5mg $989.5
3,7-Dimethoxy-3',4',5-Trihydroxyflavone FD22462 10mg $1781
Rhamnazin 99.00% CS-0143327 1mg $520
Rhamnazin 99.00% CS-0143327 5mg $1300
More product size

3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE Properties

Melting point 214-215 °C
Boiling point 591.6±50.0 °C(Predicted)
Density 1.507±0.06 g/cm3(Predicted)
pka 6.14±0.40(Predicted)
form powder
BRN 338203
InChI InChI=1S/C17H14O7/c1-22-9-6-11(19)14-13(7-9)24-17(16(21)15(14)20)8-3-4-10(18)12(5-8)23-2/h3-7,18-19,21H,1-2H3
InChIKey MYMGKIQXYXSRIJ-UHFFFAOYSA-N
SMILES C1(C2=CC=C(O)C(OC)=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1O
FDA UNII 276CK9GP9Y
UNSPSC Code 12352205
NACRES NA.25

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 93815 Rhamnazin ≥99% (HPLC) 552-54-5 5mg $484 2026-04-30 Buy
Biosynth FD22462 3,7-Dimethoxy-3',4',5-Trihydroxyflavone 552-54-5 5mg $989.5 2026-06-04 Buy
Biosynth FD22462 3,7-Dimethoxy-3',4',5-Trihydroxyflavone 552-54-5 10mg $1781 2026-06-04 Buy
ChemScene CS-0143327 Rhamnazin 99.00% 552-54-5 1mg $520 2026-06-04 Buy
ChemScene CS-0143327 Rhamnazin 99.00% 552-54-5 5mg $1300 2026-06-04 Buy
Product number Packaging Price Buy
93815 5mg $484 Buy
FD22462 5mg $989.5 Buy
FD22462 10mg $1781 Buy
CS-0143327 1mg $520 Buy
CS-0143327 5mg $1300 Buy

3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE Chemical Properties,Uses,Production

Uses

Di-O-methylated flavanol; a polyphenolic metabolite of Rhamnus disperma.

Definition

ChEBI: A dimethoxyflavone that is quercetin in which the hydroxy groups at the 3' and 7 positions have been replaced by methoxy groups.

in vivo

Rhamnazin (200 mg/kg; i.g.; daily for 25 days) inhibits breast cancer growth and angiogenesis in mice[1].
Rhamnazin (5-20 mg/kg; i.p.; once) shows strong antioxidant and anti-inflammatory properties in the rat acute lung injury model[2].

Animal Model:BALB/c nude mice, breast cancer xenograft model[1]
Dosage:200 mg/kg
Administration:Intragastric administration, daily for 25 days
Result:Dramatically suppressed tumor volumes by 47% compared with the vehicle group. Showed a significant reduction of pVEGFR2Tyr951-positive cells in tumors. Resulted in downregulation of VEGFR2 downstream molecules phosphorylation including MAPK, AKT and STAT3.

IC 50

VEGFR2: 4.68 μM (IC50)

117-39-5
552-54-5
Synthesis of 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE from Quercetin
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View Lastest Price from 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE pictures 2019-07-06 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
552-54-5
$1.00 1g 99% 100KG Career Henan Chemical Co
rhamnacene 7,3'-DiMethylquercetin NSC 678106 Quercetin 7,3'-DiMethyl Ether RHAMNAZIN(SH) 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE QUERCETIN-3,7-DIMETHYL ETHER 3,5-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one 3',7-Di-O-Methylquercetin 7,3'-Di-O-methylquercetin C.I.75700 4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy- 3,5-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one Quercetin 3’,7-Dimethyl ether 3′,7-Di-O-methyl Quercetin, CAS 552-54-5 3,7-DIMETHYLQUERCETIN RhaMnacine 552-54-5 Aromatics Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals
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