3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
- CAS No.
- 552-54-5
- Chemical Name:
- 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
- Synonyms
- RhaMnacine;3,7-DIMETHYLQUERCETIN;C.I.75700;rhamnacene;NSC 678106;RHAMNAZIN(SH);7,3'-DiMethylquercetin;7,3'-Di-O-methylquercetin;3',7-Di-O-Methylquercetin;QUERCETIN-3,7-DIMETHYL ETHER
- CBNumber:
- CB3409525
- Molecular Formula:
- C17H14O7
- Molecular Weight:
- 330.29
- MDL Number:
- MFCD00017426
- MOL File:
- 552-54-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Rhamnazin ≥99% (HPLC) | 93815 | 5mg | $484 |
| 3,7-Dimethoxy-3',4',5-Trihydroxyflavone | FD22462 | 5mg | $989.5 |
| 3,7-Dimethoxy-3',4',5-Trihydroxyflavone | FD22462 | 10mg | $1781 |
| Rhamnazin 99.00% | CS-0143327 | 1mg | $520 |
| Rhamnazin 99.00% | CS-0143327 | 5mg | $1300 |
| More product size | |||
| Melting point | 214-215 °C |
|---|---|
| Boiling point | 591.6±50.0 °C(Predicted) |
| Density | 1.507±0.06 g/cm3(Predicted) |
| pka | 6.14±0.40(Predicted) |
| form | powder |
| BRN | 338203 |
| InChI | InChI=1S/C17H14O7/c1-22-9-6-11(19)14-13(7-9)24-17(16(21)15(14)20)8-3-4-10(18)12(5-8)23-2/h3-7,18-19,21H,1-2H3 |
| InChIKey | MYMGKIQXYXSRIJ-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=C(O)C(OC)=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1O |
| FDA UNII | 276CK9GP9Y |
| UNSPSC Code | 12352205 |
| NACRES | NA.25 |
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93815 | Rhamnazin ≥99% (HPLC) | 552-54-5 | 5mg | $484 | 2026-04-30 | Buy |
| Biosynth | FD22462 | 3,7-Dimethoxy-3',4',5-Trihydroxyflavone | 552-54-5 | 5mg | $989.5 | 2026-06-04 | Buy |
| Biosynth | FD22462 | 3,7-Dimethoxy-3',4',5-Trihydroxyflavone | 552-54-5 | 10mg | $1781 | 2026-06-04 | Buy |
| ChemScene | CS-0143327 | Rhamnazin 99.00% | 552-54-5 | 1mg | $520 | 2026-06-04 | Buy |
| ChemScene | CS-0143327 | Rhamnazin 99.00% | 552-54-5 | 5mg | $1300 | 2026-06-04 | Buy |
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE Chemical Properties,Uses,Production
Uses
Di-O-methylated flavanol; a polyphenolic metabolite of Rhamnus disperma.
Definition
ChEBI: A dimethoxyflavone that is quercetin in which the hydroxy groups at the 3' and 7 positions have been replaced by methoxy groups.
in vivo
Rhamnazin (200 mg/kg; i.g.; daily for 25 days) inhibits breast cancer growth and angiogenesis in mice[1].
Rhamnazin (5-20 mg/kg; i.p.; once) shows strong antioxidant and anti-inflammatory properties in the rat acute lung injury model[2].
| Animal Model: | BALB/c nude mice, breast cancer xenograft model[1] |
| Dosage: | 200 mg/kg |
| Administration: | Intragastric administration, daily for 25 days |
| Result: | Dramatically suppressed tumor volumes by 47% compared with the vehicle group. Showed a significant reduction of pVEGFR2Tyr951-positive cells in tumors. Resulted in downregulation of VEGFR2 downstream molecules phosphorylation including MAPK, AKT and STAT3. |
IC 50
VEGFR2: 4.68 μM (IC50)
3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-06 | 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
552-54-5
|
$1.00 | 1g | 99% | 100KG | Career Henan Chemical Co |
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- 3,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
552-54-5
- $1.00
- 99%
- Career Henan Chemical Co






