ChemicalBook >> CAS DataBase List >>2,6-Dichloropyrazine
2,6-Dichloropyrazine
- CAS No.
- 4774-14-5
- Chemical Name:
- 2,6-Dichloropyrazine
- Synonyms
- M-Dichloropyrazine;6-Dichloropyrazine;2,6-Dichlor-pyrazin;2,6-CHLORO PYRAZINE;2,6-DICHLOROPYRAZINE;2,6-dichloro-pyrazin;2,6-Dichloropyrazine>Pyrazine, 2,6-dichloro-;2,6-Dichloro-1,4-diazine;2,6-Dichloropyrazine,99%
- CBNumber:
- CB3414088
- Molecular Formula:
- C4H2Cl2N2
- Molecular Weight:
- 148.98
- MDL Number:
- MFCD00006125
- MOL File:
- 4774-14-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 06:28:38
| Product description | Number | Pack Size | Price |
| 2,6-Dichloropyrazine 98% | 132497 | 5g | $50 |
| 2,6-Dichloropyrazine >99.0%(GC) | D1867 | 5g | $28 |
| 2,6-Dichloropyrazine >99.0%(GC) | D1867 | 25g | $81 |
| 2,6-Dichloropyrazine (2,6-Dichlor-pyrazin) | D3532-55 | 10g | $319 |
| 2,6-Dichloropyrazine | TRC-D435825-250G | 250g | $137 |
| More product size | |||
| Melting point | 55-58 °C (lit.) |
|---|---|
| Boiling point | 122 °C / 40mmHg |
| Density | 1.6445 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in ethanol and methanol. |
| pka | -3.11±0.10(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White to beige |
| BRN | 2439 |
| InChI | 1S/C4H2Cl2N2/c5-3-1-7-2-4(6)8-3/h1-2H |
| InChIKey | LSEAAPGIZCDEEH-UHFFFAOYSA-N |
| SMILES | Clc1cncc(Cl)n1 |
| LogP | 1.530 |
| CAS DataBase Reference | 4774-14-5(CAS DataBase Reference) |
| FDA UNII | 2NX2PQ9HSL |
| NIST Chemistry Reference | 2,6-Dichloropyrazine(4774-14-5) |
| EPA Substance Registry System | 2,6-Dichloropyrazine (4774-14-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-37/39-36/37/39-22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2,6-Dichloropyrazine price More Price(98)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 132497 | 2,6-Dichloropyrazine 98% | 4774-14-5 | 5g | $50 | 2023-06-20 | Buy |
| TCI Chemical | D1867 | 2,6-Dichloropyrazine >99.0%(GC) | 4774-14-5 | 5g | $28 | 2026-04-30 | Buy |
| TCI Chemical | D1867 | 2,6-Dichloropyrazine >99.0%(GC) | 4774-14-5 | 25g | $81 | 2026-04-30 | Buy |
| Usbiological | D3532-55 | 2,6-Dichloropyrazine (2,6-Dichlor-pyrazin) | 4774-14-5 | 10g | $319 | 2026-06-03 | Buy |
| TRC | TRC-D435825-250G | 2,6-Dichloropyrazine | 4774-14-5 | 250g | $137 | 2026-06-03 | Buy |
2,6-Dichloropyrazine Chemical Properties,Uses,Production
Chemical Properties
White Powder
Uses
2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.
Synthesis
The production method of 2,6-dichloropyrazine comprises the following steps: carrying out ammoniation and cyclization reactions of raw materials comprising methyl chloroacetate, glyoxal and the like to prepare 2-hydroxypyrazine sodium, reacting 2-hydroxypyrazine sodium with phosphorous oxychloride under the catalysis action of N,N-dimethylaminopyridine to prepare 2-chloropyrazine, and chlorinating 2-chloropyrazine by chlorine under the catalysis action of triethylamine with dimethyl formamide as a solvent to prepare 2,6-dichloropyrazine.
2,6-Dichloropyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
2-chloro-6-ethoxypyrazine
3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE
2-CHLORO-6-METHOXYPYRAZINE
2,6-Dimethoxypyrazine
2-CHLORO-6-(3-FLUOROPHENOXY) PYRAZINE
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Global( 446)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Vcan Advanced Material Co., Ltd. | +86-17306299870 +86-18652789875 | vcanam@vcanam.com | China | 49 | 58 |
| Shandong Vital Biotechnology Co., Ltd. | +8617860230571 | biotechcaroline@gmail.com | China | 87 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +8615350851019 | admin@86-ss.com | China | 999 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
View Lastest Price from 2,6-Dichloropyrazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | 2,6-Dichloropyrazine
4774-14-5
|
$66.00-99.00 | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
 |
2026-04-27 | 2,6-Dichloropyrazine
4774-14-5
|
1kg | 98% | 100tons | Shandong Vital Biotechnology Co., Ltd. | ||
 |
2026-04-10 | 2,6-Dichloropyrazine
4774-14-5
|
$2.00-5.00 | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. |
-
- 2,6-Dichloropyrazine
4774-14-5
- $66.00-99.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 2,6-Dichloropyrazine
4774-14-5
- 98%
- Shandong Vital Biotechnology Co., Ltd.
-
- 2,6-Dichloropyrazine
4774-14-5
- $2.00-5.00
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
4774-14-5(2,6-Dichloropyrazine)Related Search:
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2,6-Dichloropyrazine,99%
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2,6-Dichloropyrazine>
2,6-Dichloropyrazine USP/EP/BP
2,6-Dichloropyrazine, 97%
2,6-Dichloropyrazine，97% min
4774-14-5
C4H2CI2N2
Halogenated Heterocycles
Heterocyclic Building Blocks
Chloropyrazines, etc.
Pyrazines
Building Blocks
alkyl chloride
Building Blocks
Chemical Synthesis
Halogenated Heterocycles
Heterocyclic Building Blocks
Pesticides intermediate
Building Blocks
Halogenated Heterocycles
Heterocyclic Building Blocks
PyrazinesHeterocyclic Building Blocks
Heterocyclic Compounds
Pyrazines
Chloropyrazines, etc.
Heterocycles
Pyrazines, Pyrimidines & Pyridazines
API intermediates
Halides
Pyrazines, Pyrimidines & Pyridazines
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