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ChemicalBook >> CAS DataBase List >>10-Deacetylbaccatin III

10-Deacetylbaccatin III

CAS No.
32981-86-5
Chemical Name:
10-Deacetylbaccatin III
Synonyms
10-DAB;10-DEACETYLBACCATIN;10-DAB Ⅲ;10-DAB-III;1-Deacetylbaccatin III;Docetaxel EP Impurity E;10-Deacetyl Baccatin lll;ó;NH24841;10DBA III
CBNumber:
CB3447497
Molecular Formula:
C29H36O10
Molecular Weight:
544.59
MDL Number:
MFCD00132913
MOL File:
32981-86-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-07 16:53:29
Product description Number Pack Size Price
Docetaxel impurity E European Pharmacopoeia (EP) Reference Standard Y0001452 15 mg $127
10-desacetyl-baccatin III pharmaceutical secondary standard, certified reference material PHR3007 50 mg $640
10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) D3676 5mg $407
10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) D3676 1mg $108
10-Deacetylbaccatin III >98.0%(HPLC) D4148 100mg $92
More product size

10-Deacetylbaccatin III Properties

Melting point 231-236 °C
Boiling point 717℃
alpha -44.5 º (c=1, methanol 25 ºC)
Density 1.2007 (rough estimate)
refractive index 1.5376 (estimate)
Flash point >110°(230°F)
storage temp. Sealed in dry,Room Temperature
solubility methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)
form Powder
pka 11.50±0.70(Predicted)
color white
Water Solubility INSOLUBLE
InChIKey YWLXLRUDGLRYDR-IYNRKYTHSA-N
SMILES O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H]
LogP 0.156 (est)
CAS DataBase Reference 32981-86-5(CAS DataBase Reference)
FDA UNII 4K6EWW2Z45
UNSPSC Code 51102829
NACRES NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H319-H335-H340-H350-H373
Precautionary statements  P201-P302+P352-P305+P351+P338-P308+P313
target organs Respiratory system
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  45-38-36/37/39-28A-24/25
RIDADR  1544
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III
HS Code  29329990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Carc. 1B
Eye Irrit. 2
Muta. 1B
Skin Irrit. 2
STOT RE 2
STOT SE 3
REACH Registrations Active
NFPA 704
0
4 0

10-Deacetylbaccatin III price More Price(81)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001452 Docetaxel impurity E European Pharmacopoeia (EP) Reference Standard 32981-86-5 15 mg $127 2026-04-30 Buy
Sigma-Aldrich PHR3007 10-desacetyl-baccatin III pharmaceutical secondary standard, certified reference material 32981-86-5 50 mg $640 2026-04-30 Buy
Sigma-Aldrich D3676 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) 32981-86-5 5mg $407 2026-04-30 Buy
Sigma-Aldrich D3676 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) 32981-86-5 1mg $108 2023-06-20 Buy
TCI Chemical D4148 10-Deacetylbaccatin III >98.0%(HPLC) 32981-86-5 100mg $92 2026-04-30 Buy
Product number Packaging Price Buy
Y0001452 15 mg $127 Buy
PHR3007 50 mg $640 Buy
D3676 5mg $407 Buy
D3676 1mg $108 Buy
D4148 100mg $92 Buy

10-Deacetylbaccatin III Chemical Properties,Uses,Production

Chemical Properties

10-Deacetylbaccatin III is White Solid

Uses

10-Deacetylbaccatin III is a intermediate in the synthesis of Taxol and derivatives

Uses

10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.

Uses

10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the le

Definition

ChEBI: 10-deacetylbaccatin III is a tetracyclic diterpenoid and a secondary alpha-hydroxy ketone. It is functionally related to a baccatin III.

General Description

10-Deacetylbaccatin III, also known as Paclitaxel Impurity 19, is an impurity of Paclitaxel. Paclitaxel is a chemotherapy drug. Chemotherapy is a treatment that destroys cancer cells using anti-cancer drugs. Paclitaxel is the non-branded name of the drug, but you may hear it called by one of its brand names such as Taxol. Some people are given a drug called nab-paclitaxel (Abraxane).

Biological Activity

10-dab (also known as 10-deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the pacific yew tree taxus brevifolia as well as other species of the genus taxus. due to the low availability of taxol from its natural sources, 10-dab is used as a raw material for the preparation of taxol and its derivatives. being easily extracted from the annual cute of the yew leaves, 10-dab has a very folded chemical structure with the α hydroxyl group hindered at c-13 easily to form a hydrogen bond with the 4α acetyl group.f. gueritte-voegelein, v. senilh, b. david, d. guenard and p. potier. chemical studies of 10-deacetyl baccatin iii hemisynthesis of taxol derivatives. tetrahedron 1986; 42(16): 4451-4460

32981-90-1
32981-86-5
Synthesis of 10-Deacetylbaccatin III from ACETYLBACCATIN III, 7-(P)

10-Deacetylbaccatin III Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 682)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei baicao biology science and technology co., ltd
+86-19131911055 +8617824879454 zhang@hbbocao.com China 1029 58
Guangzhou Tosun Pharmaceutical Limited
+86-18124244216 +86-18124244216 info@upharm.cn China 998 58
LIDE PHARMACEUTICALS LIMITED
+86-86-2558409506 +8618913920737 louis@lidepharma.com China 300 58
Henan Fengda Chemical Co., Ltd
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+86-18062099985 Amyjiyunzen@yeah.net China 672 58
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Jiangsu Yew Pharmaceutical Co., Ltd.
+86-510-66865338 +86-189-2133-5032 @ junwenjiang@live.cn CHINA 30 60

View Lastest Price from 10-Deacetylbaccatin III manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
10-Deacetylbaccatin III pictures 2026-07-15 10-Deacetylbaccatin III
32981-86-5
$6666.00 2KG 99 100kg Baoji Guokang Healthchem Co., Ltd.
10-Deacetylbaccatin III pictures 2026-07-09 10-Deacetylbaccatin III
32981-86-5
$1.40-35.00 1kg 99% Henan Fengda Chemical Co., Ltd
10-Deacetylbaccatin III pictures 2026-07-07 10-Deacetylbaccatin III
32981-86-5
$29.00 99.91% 10g TargetMol Chemicals Inc.

10-Deacetylbaccatin III Spectrum

10-deacetylbaccatin11 10-deacetylbaccatiniii(extaxusbaccata) 10-DEACETYLBACCATIN III FROMTAXUS BACCAT A 10-Dab98.5% 10-Deacetylbaccatine(III) 10-Deacetyl Baccatin ¢ 10-Deacetylbaccatine 10-DAB III(10-DEACETYL BACCATIN III) 99% DEACETYLBACCATIN-III, 10(P) 10-DAB(10-deacetylbaccatin) 10-Deacetyl DESACETYLBACCATINE BACCATIN III, 10-DEACETYL- 10-Deacetylbaccatin III 10-O-DEACETYLBACCATIN III Docetaxel IMpurity E (10-Deacetyl Baccatin III) ó 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)- Docetaxel impurity E 10-Deacetylbaccatin III, >=99% 10-deacetyl Chiba Cardin Ⅲ 12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3 (2AR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl- 10-DEACETYLBACCATIN III (EX TAXUS BACCATA), CONTAINS CA 0.5 MOLE OF METHANOL 95% 10-DEACETYL BACCATIN (10-DAB ) 10-Desacetylbaccatin III 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one,12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-,[2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]- 12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one 10-DEACETYLBACCATIN III, 95%, FROM TAXUS BACCATA 10-Deacetyl Baccatin ¢ó 12b-(Acetyloxy)-12-(Benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro-4,6,9,11-Tetrahydroxy-4a,8,13,13-Tetramethyl-7,11-Methano-5h-Cyclodeca[3,4] 10-Deacetylbaccatin III ,97% 10-Decaacetyl baccatin III 10DBA III 10-Deacetyl baccatine IIII 10-Deacetylbaccatin Ⅲ(10-DAB) 5β,20-Epoxy-4-(acetyloxy)-1,7β,10β,13α-tetrahydroxy-9-oxotax-11-en-2α-yl benzoate (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one Deacetylbaccatin III high quality 10-deacetylbacctin Ⅲ(10-DAB) CAS 32981-86-5 CAS NO.32981-86-5 10-Deacetylbaccatin III 32981-86-5 Paclitaxel Impurity 19 Docetaxel EP impurity E,10-desacetyl-baccatin III 10-Deacetylbacatin III Docetaxel Impurity 5(Docetaxel EP Impurity E) NH24841 10-DAB:10-Deacetylbaccatin III Docetaxel EP Impurity E (10-Deacetyl Baccatin III) 10-DeacetylbaccatinIII> Docetaxel impurity E CRS 3-(5-chloro-2-fluorobenzyl)isonicotinic acid 10-Deacetylbaccatin III USP/EP/BP 10-Deacetylbaccatin IIIQ: What is 10-Deacetylbaccatin III Q: What is the CAS Number of 10-Deacetylbaccatin III Q: What is the storage condition of 10-Deacetylbaccatin III Q: What are the applications of 10-Deacetylbaccatin III 10-Deacetylbaccatin III, 95%, 10-Deacetyl Baccatin lll 10-DAB Ⅲ Paclitaxel Impurity 29 (See C4X-16195) Phenol,4-chloro-7-iodo-
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