2-Methoxy-3-nitropyridine
- CAS No.
- 20265-35-4
- Chemical Name:
- 2-Methoxy-3-nitropyridine
- Synonyms
- 2-METHOXY-3-NITROPYRIDINE;3-Nitro-2-methoxypyridine;Pyridine, 2-methoxy-3-nitro-;2-Methoxy-3-nitropyridine>METHYL 3-NITRO-2-PYRIDINYL ETHER;2-Methoxy-3-nitropyridine ISO 9001：2015 REACH
- CBNumber:
- CB3476383
- Molecular Formula:
- C6H6N2O3
- Molecular Weight:
- 154.12
- MDL Number:
- MFCD00023459
- MOL File:
- 20265-35-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Methoxy-3-nitropyridine >98.0%(GC) | M1395 | 5g | $110 |
| 2-Methoxy-3-nitropyridine >98.0%(GC) | M1395 | 25g | $347 |
| 2-Methoxy-3-nitropyridine | FM07068 | 100g | $150 |
| 2-Methoxy-3-nitropyridine | FM07068 | 250g | $150 |
| 2-Methoxy-3-nitropyridine | FM07068 | 500g | $180 |
| More product size | |||
| Melting point | 53-55°C |
|---|---|
| Boiling point | 247.9±20.0 °C(Predicted) |
| Density | 1.300±0.06 g/cm3(Predicted) |
| Flash point | >110℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | -0+-.0.10(Predicted) |
| color | White to Amber |
| BRN | 138199 |
| InChI | InChI=1S/C6H6N2O3/c1-11-6-5(8(9)10)3-2-4-7-6/h2-4H,1H3 |
| InChIKey | WZNQCVOSOCGWJG-UHFFFAOYSA-N |
| SMILES | C1(OC)=NC=CC=C1[N+]([O-])=O |
| CAS DataBase Reference | 20265-35-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H319-H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22-41-37/38 | |||||||||
| Safety Statements | 26-36/37/39-22-36-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
2-Methoxy-3-nitropyridine price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1395 | 2-Methoxy-3-nitropyridine >98.0%(GC) | 20265-35-4 | 5g | $110 | 2026-04-30 | Buy |
| TCI Chemical | M1395 | 2-Methoxy-3-nitropyridine >98.0%(GC) | 20265-35-4 | 25g | $347 | 2026-04-30 | Buy |
| Biosynth | FM07068 | 2-Methoxy-3-nitropyridine | 20265-35-4 | 100g | $150 | 2026-06-04 | Buy |
| Biosynth | FM07068 | 2-Methoxy-3-nitropyridine | 20265-35-4 | 250g | $150 | 2026-06-04 | Buy |
| Biosynth | FM07068 | 2-Methoxy-3-nitropyridine | 20265-35-4 | 500g | $180 | 2026-06-04 | Buy |
2-Methoxy-3-nitropyridine Chemical Properties,Uses,Production
Uses
2-Methoxy-3-nitropyridine is a pyridine compound used as a reagent in chemical reactions or as an intermediate component in organic synthesis. It can be reduced to amines and then converted to N-substituted derivatives.
Preparation
2-Methoxy-3-nitropyridine can be prepared by methylation of 2-hydroxy-3-nitropyridine[1].
Synthesis
5470-18-8
20265-35-4
Example 12 Synthesis of 2-methoxy-3-nitropyridine STR27: 2-chloro-3-nitropyridine (25 g, 0.157 mol) was suspended in methanol (300 ml), followed by addition of sodium methanolate (17 g, 0.315 mol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, some of the solvent was removed by distillation under reduced pressure. The remaining reaction mixture was diluted with water (1 liter) and filtered to collect the precipitate precipitated. The resulting white solid was washed with copious amounts of water and subsequently dried under vacuum to afford the target product 2-methoxy-3-nitropyridine (18.2 g, 75% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 8.42 (dd, J = 5,2 Hz, 1H); 8.28 (dd, J = 8,2 Hz, 1H); 7.06 (dd, J = 8,5 Hz, 1H); 4.13 (s, 3H).
References
[1] GRUBER W. PYRIDINE DERIVATIVES: PART VI MALONATIONS OF SUBSTITUTED NITROPYRIDINES[J]. Canadian Journal of Chemistry, 1953. DOI:10.1139/V53-152.
2-Methoxy-3-nitropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Nantong Haigine Pharma Technology Co., Ltd | 0086-513-86266699 | CHINA | 156 | 58 | |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 2-Methoxy-3-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | 2-Methoxy-3-nitropyridine
20265-35-4
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-11-18 | 2-Methoxy-3-nitropyridine
20265-35-4
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2024-03-28 | 2-Methoxy-5-nitropyridine
20265-35-4
|
25kg | 98% | PNP Biotech Co. Ltd |
-
- 2-Methoxy-3-nitropyridine
20265-35-4
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Methoxy-3-nitropyridine
20265-35-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Methoxy-5-nitropyridine
20265-35-4
- $0.00
- 98%
- PNP Biotech Co. Ltd
