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H-7 DIHYDROCHLORIDE

H-7 DIHYDROCHLORIDE structure

CAS No.: 108930-17-2

Chemical Name:: H-7 DIHYDROCHLORIDE

Synonyms: H-7;H-7 DIHYDROCHLORIDE;H-7 (hydrochloride);H-7 dihydrochloride,98%;H7 dihydrochloride,H 7 dihydrochloride;Protein kinase inhibitor H-7 dihydrochloride;1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL;1-(5-isoquinolinylsulfonyl)-2-methylpiperazine 2HCl;H-7, Dihydrochloride - CAS 108930-17-2 - Calbiochem;(+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL

CBNumber:: CB3725838

Molecular Formula:: C14H19Cl2N3O2S

Molecular Weight:: 364.29

MDL Number:: MFCD00036961

MOL File:: 108930-17-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-18 10:06:17

Product description	Number	Pack Size	Price
H-7 dihydrochloride ≥98% (HPLC)	I7016	5mg	$251
H-7 (hydrochloride) ≥98%	21434	5mg	$63
H-7 (hydrochloride) ≥98%	21434	10mg	$105
H-7 (hydrochloride) ≥98%	21434	25mg	$242
H-7 (hydrochloride) ≥98%	21434	50mg	$423

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H-7 DIHYDROCHLORIDE Properties

Melting point	215-225 °C
storage temp.	2-8°C
solubility	H₂O: 20 mg/mL
form	Light yellow lyophilized solid
color	White to Off-White
Water Solubility	water: 20mg/mL
BRN	5840763
InChI	1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H
InChIKey	OARGPFMFRLLKPF-UHFFFAOYSA-N
SMILES	Cl.Cl.CC1CNCCN1S(=O)(=O)c2cccc3cnccc23
CAS DataBase Reference	108930-17-2(CAS DataBase Reference)
FDA UNII	55VT8U9HB1
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	24/25
WGK Germany	3
F	10
Storage Class	11 - Combustible Solids

H-7 DIHYDROCHLORIDE price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	I7016	H-7 dihydrochloride ≥98% (HPLC)	108930-17-2	5mg	$251	2026-04-30	Buy
Cayman Chemical	21434	H-7 (hydrochloride) ≥98%	108930-17-2	5mg	$63	2026-04-30	Buy
Cayman Chemical	21434	H-7 (hydrochloride) ≥98%	108930-17-2	10mg	$105	2026-04-30	Buy
Cayman Chemical	21434	H-7 (hydrochloride) ≥98%	108930-17-2	25mg	$242	2026-04-30	Buy
Cayman Chemical	21434	H-7 (hydrochloride) ≥98%	108930-17-2	50mg	$423	2026-04-30	Buy

Product number	Packaging	Price	Buy
I7016	5mg	$251	Buy
21434	5mg	$63	Buy
21434	10mg	$105	Buy
21434	25mg	$242	Buy
21434	50mg	$423	Buy

H-7 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Uses

A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases

Uses

H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.

Definition

ChEBI: A hydrochloride salt prepared from anileridine and two molar equivalents of hydrogen chloride.

General Description

A broad-based, cell-permeable, reversible, ATP-competitive serine-threonine kinase inhibitor. Potent inhibitor of myosin light chain kinase (K_i = 97 μM), protein kinase A (K_i = 3.0 μM), protein kinase C (K_i = 6 μM), and protein kinase G (K_i = 5.8 μM). Induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells. Also inhibits telomerase activity in quercetin-, H-89-, or herbimycin A-treated NPC-076 cells.

Biochem/physiol Actions

Target Ki: 3.0 μM, 97 μM, 6.0 μM, 5.8 μM against protein kinase A , myosin light chain kinase, protein kinase C , and protein kinase G, respectively

storage

Store at RT

H-7 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

H-7 DIHYDROCHLORIDE Suppliers

Global( 91)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32343	55
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9891	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
Mainchem Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chemsky（shanghai）International Co.,Ltd.	50
BOC Sciences	65
Shanghai T&W Pharmaceutical Co., Ltd.	58

View Lastest Price from H-7 DIHYDROCHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-16	Protein kinase inhibitor H-7 dihydrochloride 108930-17-2	$32.00-111.00		99.81%	10g	TargetMol Chemicals Inc.

Protein kinase inhibitor H-7 dihydrochloride
108930-17-2
$32.00-111.00
99.81%
TargetMol Chemicals Inc.

H-7 DIHYDROCHLORIDE Spectrum

H-7 DIHYDROCHLORIDE(108930-17-2)¹HNMR

108930-17-2(H-7 DIHYDROCHLORIDE)Related Search:

1-METHANESULFONYL-PIPERAZINE 2-Methylpiperazine PIPERAZINE DIHYDROCHLORIDE 1-BENZENESULFONYL-PIPERAZINE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE

1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE 1-(3-TRIFLUOROMETHYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE 1-(3-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE 1,3-PROPANEDIAMINE DIHYDROCHLORIDE 1,4'-BIPIPERIDINE DIHYDROCHLORIDE,[1,4']BIPIPERIDINYL DIHYDROCHLORIDE

1,4-BENZENEDIAMINE DIHYDROCHLORIDE [1,4']BIPIPERIDINYL DIHYDROCHLORIDE 10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE,1-(3-Methylphenyl)piperazine dihydrochloride 1-(4-Bromophenyl)piperazine

DILAZEP DIHYDROCHLORIDE 1,4-Diaminobutane dihydrochloride 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

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H-7 DIHYDROCHLORIDE H-7 (+/-)-1-(5-ISOQUINOLINESULPHONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE (+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE 2HCL (-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, DI-HCL SALT (+/-)-1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE DIHYDROCHLORIDE 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine 2HCl H-7 dihydrochloride,98% Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride 5-[(2-Methyl-1-piperazinyl)sulfonyl]isoquinoline Hydrochloride H-7, Dihydrochloride - CAS 108930-17-2 - Calbiochem H-7 (hydrochloride) H7 dihydrochloride,H 7 dihydrochloride 5-((2-Methylpiperazin-1-yl)sulfonyl)isoquinoline dihydrochloride Protein kinase inhibitor H-7 dihydrochloride 108930-17-2 C14H19Cl2N3O2S Cell Biology Serine/Threonine Kinase Inhibitors Kinase/Phosphatase Biology Protein kinase A and protein kinase C (PKA and PKC) BioChemical Cell Signaling and Neuroscience Protein Kinase Inhibitors and Activators

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H-7 DIHYDROCHLORIDE

H-7 DIHYDROCHLORIDE Properties

SAFETY

Risk and Safety Statements

H-7 DIHYDROCHLORIDE price More Price(48)

H-7 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

Uses

Uses

Definition

General Description

Biochem/physiol Actions

storage

H-7 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

H-7 DIHYDROCHLORIDE Suppliers

View Lastest Price from H-7 DIHYDROCHLORIDE manufacturers

H-7 DIHYDROCHLORIDE Spectrum

108930-17-2(H-7 DIHYDROCHLORIDE)Related Search: