2-Nitrochlorobenzene
- CAS No.
- 88-73-3
- Chemical Name:
- 2-Nitrochlorobenzene
- Synonyms
- 1-CHLORO-2-NITROBENZENE;ONCB;2-CHLORONITROBENZENE;O-CHLORONITROBENZENE;O-NITROCHLOROBENZENE;C6H4ClNO2;ORTHO-CHLORONITROBENZENE;2-Chloro-1-nitrobenzene;2-cnb;lenvaint-F
- CBNumber:
- CB3767980
- Molecular Formula:
- C6H4ClNO2
- Molecular Weight:
- 157.55
- MDL Number:
- MFCD00007061
- MOL File:
- 88-73-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-Chloro-2-nitrobenzene 99% | 185760 | 250g | $54 |
| 1-Chloro-2-nitrobenzene 99% | 185760 | 1kg | $87.7 |
| 2-Chloronitrobenzene >99.0%(GC) | C0220 | 25g | $17 |
| 2-Chloronitrobenzene >99.0%(GC) | C0220 | 500g | $60 |
| o-Nitrochlorobenzene Asreported | 285511 | 100g | $290 |
| More product size | |||
| Melting point | 31-33 °C (lit.) |
|---|---|
| Boiling point | 246 °C (lit.) |
| Density | 1.348 g/mL at 25 °C (lit.) |
| vapor density | 5.4 (vs air) |
| vapor pressure | 0.04 mm Hg ( 25 °C) |
| refractive index | 1.5520 (estimate) |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | alcohol: soluble |
| form | Fused Crystalline Mass |
| color | Yellow |
| PH | 6 (0.4g/l, H2O, 20℃) |
| explosive limit | 1.15-13.1%(V) |
| Water Solubility | 0.43 g/L (20 ºC) |
| Merck | 14,2151 |
| BRN | 509273 |
| Henry's Law Constant | 1.1×100 mol/(m3Pa) at 25℃, Altschuh et al. (1999) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, strong bases, alkali metals. |
| InChI | 1S/C6H4ClNO2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H |
| InChIKey | BFCFYVKQTRLZHA-UHFFFAOYSA-N |
| SMILES | [O-][N+](=O)c1ccccc1Cl |
| CAS DataBase Reference | 88-73-3(CAS DataBase Reference) |
| FDA UNII | D1YI9R2K8O |
| Proposition 65 List | 2-Chloronitrobenzene |
| IARC | 2B (Vol. 65, 123) 2020 |
| NIST Chemistry Reference | Benzene, 1-chloro-2-nitro-(88-73-3) |
| EPA Substance Registry System | o-Chloronitrobenzene (88-73-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P310-P302+P352+P312-P361+P364 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 22-24-52-53-52/53 | |||||||||
| Safety Statements | 36/37/39-45-60-38-28A | |||||||||
| RIDADR | UN 1578 6.1/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CZ0875000 | |||||||||
| Autoignition Temperature | 500 °F | |||||||||
| Hazard Note | Toxic | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29049085 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Oral |
|||||||||
| Hazardous Substances Data | 88-73-3(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 100ml (liquid) or 0.5 Kg (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
2-Nitrochlorobenzene price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 185760 | 1-Chloro-2-nitrobenzene 99% | 88-73-3 | 250g | $54 | 2026-04-30 | Buy |
| Sigma-Aldrich | 185760 | 1-Chloro-2-nitrobenzene 99% | 88-73-3 | 1kg | $87.7 | 2026-04-30 | Buy |
| TCI Chemical | C0220 | 2-Chloronitrobenzene >99.0%(GC) | 88-73-3 | 25g | $17 | 2026-04-30 | Buy |
| TCI Chemical | C0220 | 2-Chloronitrobenzene >99.0%(GC) | 88-73-3 | 500g | $60 | 2026-04-30 | Buy |
| Usbiological | 285511 | o-Nitrochlorobenzene Asreported | 88-73-3 | 100g | $290 | 2026-06-03 | Buy |
2-Nitrochlorobenzene Chemical Properties,Uses,Production
Chemical Properties
yellow solid with a characteristic odour
Uses
1-Chloro-2-nitrobenzene was used in the synthesis of 1-hydroxybenzotriazole derivatives. It is important as a precursor to other compounds due to the two reactive sites present on the molecule.
Uses
Chemical intermediate in manufacture of dyes, picric acid, lumber preservatives, and diaminophenol hydrochloride (a photographic developer)
Uses
Intermediate, especially for dyes.
Definition
ChEBI: 1-chloro-2-nitrobenzene is a C-nitro compound that is nitrobenzene in which one of the ortho- hydrogens has been replaced by chlorine. It is a C-nitro compound and a member of monochlorobenzenes.
Production Methods
Nitration of chlorobenzene with mixed acid (30/56/14) typically gives an isomer mix in 98 % yield consisting of 34 – 36 % 2-Nitrochlorobenzene, 63 – 65 % 4- chloronitrobenzene, and only ca. 1 % 3- chloronitrobenzene. The ortho – para ratio of about 0.55 is in sharp contrast to the 1.6 obtained with nitrotoluene isomers. As with the nitration of toluene, much work has been done on isomer control so that the producer might have some flexibility towards the balance of isomer demand. Although no major change in ratio has been achieved, the situation is better for nitrochlorobenzene than nitrotoluenes, because the favored isomer is in much greater demand. In further contrast to the nitration of toluene, the nitration of chlorobenzene in the presence of phosphoric acid decreases the proportion of 4-Nitrochlorobenzene, and the use of phosphoric acid in the presence of a transition-metal catalyst is said to increase the ortho – para ratio to ca. 0.8.
General Description
Yellow crystals with an aromatic odor. Sinks in water.
Air & Water Reactions
2-Nitrochlorobenzene may be sensitive to prolonged exposure to air and light. Insoluble in water.
Reactivity Profile
O-NITROCHLOROBENZENE is incompatible with strong bases and strong oxidizing agents. 2-Nitrochlorobenzene will react with ammonia.
Hazard
Toxic by inhalation and ingestion. Combustible. Questionable carcinogen.
Health Hazard
INHALATION: Headache, languour, anemia. Irritation of nose and throat, cyanosis, shallow respiration, convulsions, and coma. EYES: Irritation. SKIN: Irritation. INGESTION: Forms methemoglobin giving rise to cyanosis and blood changes.
Flammability and Explosibility
Not classified
Safety Profile
Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Poison by ingestion, skin contact, and probably inhalation. Combustible when exposed to heat or flame. To fight fire, use water, foam. Potentially explosive reaction with ammonia at 160℃/30 bar. When heated to decomposition it emits toxic fumes of Cl-, NOx, and phosgene. See also other chloronitrobenzene entries and NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Purification Methods
Crystallise it from EtOH, MeOH or pentane (charcoal). [Beilstein 5 IV 721.]
Toxics Screening Level
The Initial Risk Screening Level (IRSL) for 1-chloro-2-nitrobenzene (CAS# 88-73-3) is 0.21 μg/m3 based on an annual averaging time.
2-Nitrochlorobenzene Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
1of7
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43414 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Alchemie Shanghai Co.,Ltd. | +8615921545397 | cindy_hu@alchemie-shanghai.com | China | 133 | 58 |
| Hebei Yongtai Supply Chain Management Co., Ltd. | 15130657697 15130657697 | 1922148008@qq.com | China | 55 | 58 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11705 | 57 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13350 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939; 15221275939 | shenlinxing@macklin.cn | China | 15781 | 55 |
88-73-3(2-Nitrochlorobenzene)Related Search:
1of4
