(R)-(+)-Propylene carbonate
- CAS No.
- 16606-55-6
- Chemical Name:
- (R)-(+)-Propylene carbonate
- Synonyms
- R-Prpylene Carbonate;(R)-PROPYLENE CARBONATE;(R)-Propandiolcarbonate;(R)-PropyleneCarbonate>(R)-(+)-PROPYLENE CARBONATE;(R)-1,2-PROPYLENE CARBONATE;(R)-1,2-PROPANEDIOL CARBONATE;(R)-Propylene Carbonate,99%e.e.;(R)-(+)-1,2-PROPYLENE CARBONATE;(R)-5-Methyl-1,3-dioxolan-2-one
- CBNumber:
- CB3783423
- Molecular Formula:
- C4H6O3
- Molecular Weight:
- 102.09
- MDL Number:
- MFCD00798265
- MOL File:
- 16606-55-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (R)-(+)-Propylene carbonate 98% | 540013 | 5g | $81.1 |
| (R)-Propylene Carbonate >98.0%(GC) | P1485 | 5g | $42 |
| (R)-Propylene Carbonate >98.0%(GC) | P1485 | 25g | $205 |
| (R)-1,2-Propylene Carbonate | P9052-55M | 100mg | $403 |
| (R)-1,2-Propylene carbonate | 287102 | 5g | $312 |
| More product size | |||
| Boiling point | 240 °C(lit.) |
|---|---|
| Density | 1.189 g/mL at 25 °C(lit.) |
| vapor pressure | 0.59 psi ( 20 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Sparingly) |
| form | Oil |
| color | Clear Colourless to Pale Yellow |
| Specific Gravity | 1.189 |
| optical activity | [α]20/D +2°, neat |
| Water Solubility | 175 g/L (25 ºC) |
| InChI | InChI=1S/C4H6O3/c1-3-2-6-4(5)7-3/h3H,2H2,1H3/t3-/m1/s1 |
| InChIKey | RUOJZAUFBMNUDX-GSVOUGTGSA-N |
| SMILES | O1C[C@@H](C)OC1=O |
| CAS DataBase Reference | 16606-55-6(CAS DataBase Reference) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FF9650000 | |||||||||
| HS Code | 29329990 | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
(R)-(+)-Propylene carbonate price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 540013 | (R)-(+)-Propylene carbonate 98% | 16606-55-6 | 5g | $81.1 | 2026-04-30 | Buy |
| TCI Chemical | P1485 | (R)-Propylene Carbonate >98.0%(GC) | 16606-55-6 | 5g | $42 | 2026-04-30 | Buy |
| TCI Chemical | P1485 | (R)-Propylene Carbonate >98.0%(GC) | 16606-55-6 | 25g | $205 | 2026-04-30 | Buy |
| Usbiological | P9052-55M | (R)-1,2-Propylene Carbonate | 100mg | $403 | 2026-06-04 | Buy | |
| Usbiological | 287102 | (R)-1,2-Propylene carbonate | 16606-55-6 | 5g | $312 | 2026-06-03 | Buy |
(R)-(+)-Propylene carbonate Chemical Properties,Uses,Production
Description
(R)-(+)-Propylene carbonate, also known as (R)-1,2-Propanediol cyclic carbonate, presents as a colorless to pale yellow liquid. This compound should keep the container tightly closed and stored in a cool and dark place. For best results, store under inert gas, protected from moisture, as this substance is moisture-sensitive. (R)-(+)-Propylene carbonate is incompatible with oxidizing agents and acids. This chemical causes skin irritation as well as serious eye irritation.
Chemical Properties
Colorless to light yellow liqui
Uses
(R)-1,2-Propylene Carbonate (cas# 16606-55-6) is a compound useful in organic synthesis.
Synthesis
4254-14-2
105-58-8
16606-55-6
The general procedure for the synthesis of R-propylene carbonate from (R)-1,2-propanediol and diethyl carbonate was as follows: (R)-1,2-propanediol (38.05 kg, 500 mol) was added to a glass-lined reactor, followed by the addition of diethyl carbonate (70.88 kg, 600 mol) and sodium ethoxide (3.4 kg, 50 mol). The reaction mixture was heated to 105-110 °C and maintained for 8 hours. After completion of the reaction, unreacted diethyl carbonate was removed by distillation under reduced pressure. After the reaction mixture was cooled to room temperature, the insoluble material was removed by filtration. Finally, the solvent was removed by evaporation of the filtrate to afford R-propylene carbonate (34.24 kg, purity ≥99%) in 90% yield.
References
[1] Patent: CN105859781, 2016, A. Location in patent: Paragraph 0011-0012
[2] Patent: US2010/216822, 2010, A1. Location in patent: Page/Page column 13
[3] Tetrahedron Letters, 1998, vol. 39, # 14, p. 1853 - 1856
[4] Patent: EP1243590, 2002, A2. Location in patent: Page 9
[5] Patent: CN102977146, 2016, B. Location in patent: Paragraph 0016; 0021; 0023
(R)-(+)-Propylene carbonate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Qiwei Pharmatech Co.,Ltd | 13282840061 | mw@qwpharmatech.com | China | 109 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shenzhen Nexcon Pharmatechs Ltd. | +86-0755-89396905 +86-18025329037 | admin@nexconn.com | China | 5281 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3587 | 58 |
View Lastest Price from (R)-(+)-Propylene carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-30 | (R)-(+)-Propylene carbonate
16606-55-6
|
1KG | 99% | 20000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-03-20 | (R)-(+)-Propylene carbonate
16606-55-6
|
$10.00 | 1KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-01 | (R)-(+)-Propylene carbonate
16606-55-6
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- (R)-(+)-Propylene carbonate
16606-55-6
- 99%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- (R)-(+)-Propylene carbonate
16606-55-6
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- (R)-(+)-Propylene carbonate
16606-55-6
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
