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ChemicalBook >> CAS DataBase List >>2,6-Dichlorobenzyl acetonitrile

2,6-Dichlorobenzyl acetonitrile

CAS No.
3215-64-3
Chemical Name:
2,6-Dichlorobenzyl acetonitrile
Synonyms
2,6-DICHLOROPHENYLACETONITRILE;Guanfacine Impurity 13;2,6-DICHLOROBENZYL CYANIDE;6-Dichlorophenylacetontrile;2,6-DichlorobenzylCyanide>2,6-DICHLOROPHENYLACETONTRILE;2,6-Dichlorobenzeneacetonitrile;2,6-dichlorobenzyl acetonitrile;2,6-Dichloropenzyl Acetonitrile;Benzeneacetonitrile, 2,6-dichloro-
CBNumber:
CB3784389
Molecular Formula:
C8H5Cl2N
Molecular Weight:
186.04
MDL Number:
MFCD00001901
MOL File:
3215-64-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:06:07
Product description Number Pack Size Price
2,6-Dichlorophenylacetonitrile 97% 126012 25g $185
2,6-Dichlorobenzyl Cyanide >98.0%(GC) D1793 25g $68
2,6-Di chloro phenyl acetonitrile Asreported 271060 5g $289
2,6-Di chloro phenyl acetonitrile Asreported 271060 10g $383
2,6-Di chloro phenyl acetonitrile Asreported 271060 25g $493
More product size

2,6-Dichlorobenzyl acetonitrile Properties

Melting point 73-75 °C (lit.)
Boiling point 306.06°C (rough estimate)
Density 1.4274 (rough estimate)
refractive index 1.5690 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form Crystalline Powder
color White to light yellow
BRN 1910482
Exposure limits NIOSH: IDLH 25 mg/m3
InChI 1S/C8H5Cl2N/c9-7-2-1-3-8(10)6(7)4-5-11/h1-3H,4H2
InChIKey AOEJUUCUKRUCEF-UHFFFAOYSA-N
SMILES Clc1cccc(Cl)c1CC#N
CAS DataBase Reference 3215-64-3(CAS DataBase Reference)
FDA UNII YDY3AJ66GX
NIST Chemistry Reference 2,6-Dichlorophenylacetic acid nitrile(3215-64-3)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-37/39-36/37/39
RIDADR  3439
WGK Germany  3
HazardClass  6.1
PackingGroup  III
HS Code  29269095
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
NFPA 704
1
2 0

2,6-Dichlorobenzyl acetonitrile price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 126012 2,6-Dichlorophenylacetonitrile 97% 3215-64-3 25g $185 2023-01-07 Buy
TCI Chemical D1793 2,6-Dichlorobenzyl Cyanide >98.0%(GC) 3215-64-3 25g $68 2026-04-30 Buy
Usbiological 271060 2,6-Di chloro phenyl acetonitrile Asreported 3215-64-3 5g $289 2026-06-03 Buy
Usbiological 271060 2,6-Di chloro phenyl acetonitrile Asreported 3215-64-3 10g $383 2026-06-03 Buy
Usbiological 271060 2,6-Di chloro phenyl acetonitrile Asreported 3215-64-3 25g $493 2026-06-03 Buy
Product number Packaging Price Buy
126012 25g $185 Buy
D1793 25g $68 Buy
271060 5g $289 Buy
271060 10g $383 Buy
271060 25g $493 Buy

2,6-Dichlorobenzyl acetonitrile Chemical Properties,Uses,Production

Chemical Properties

White to light yellow crystalline powder

Uses

2,6-Dichlorophenylacetonitrile was found to degrade rapidly in non-sterile soils but not in azide treated soils.

General Description

2,6-Dichlorophenylacetonitrile was found to degrade rapidly in non-sterile soils but not in azide treated soils.

Synthesis

POTASSIUM CYANIDE

151-50-8

2,6-Dichlorobenzyl chloride

2014-83-7

2,6-Dichlorobenzyl acetonitrile

3215-64-3

Example 13-(2,6-dichloro-phenyl)-6-(2,4-difluoro-phenylamino)-1-diethyl-pyrazolo[1,5-a]pyrimidin-2-one was synthesized as follows: Step 1 (Synthesis of 2,6-dichlorophenylacetonitrile): a solution of potassium cyanide (26 g, 400.00 mmol) and 18-crown-6 (0.05 g) in water (60 mL) was added to a 500 mL round bottom flask. Subsequently, an ethanol (300 mL) solution of 2,6-dichlorobenzyl chloride (40 g, 206.24 mmol) was added to this solution. The reaction mixture was stirred under reflux conditions for 1 to 3 hours and the progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio ethyl acetate: petroleum ether = 1:4). After completion of the reaction, the mixture was concentrated to dryness using a rotary evaporator. The concentrated residue was transferred to a dispensing funnel and washed with water (5 x 100 mL) to afford 35.4 g (95% yield) of 2-(2,6-dichlorophenyl)acetonitrile as a white solid. The product can be used directly in the next reaction without further purification.

References

[1] Patent: WO2007/15866, 2007, A2. Location in patent: Page/Page column 29; 31

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View Lastest Price from 2,6-Dichlorobenzyl acetonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-Dichlorobenzyl acetonitrile pictures 2026-03-20 2,6-Dichlorobenzyl acetonitrile
3215-64-3
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2,6-Dichlorobenzyl acetonitrile pictures 2025-02-13 2,6-Dichlorobenzyl acetonitrile
3215-64-3
$7.00-10.00 1kg 99.99% 10 tons Shandong Deshang Chemical Co., Ltd.
2,6-Dichlorobenzyl acetonitrile pictures 2024-07-11 2,6-Dichlorobenzyl acetonitrile
3215-64-3
$1.00 1KG 98% 20T Shaanxi Dideu Medichem Co. Ltd
2,6-DICHLOROBENZYL CYANIDE 2,6-dichlorobenzyl acetonitrile 2,6-Dichlorobenzeneacetonitrile Acetonitrile, (2,6-dichlorophenyl)- 2,6-Dichlorophenylacetic acid nitrile 2 6-DICHLOROBENZYL CYANIDE 99% (GC) 2,6-DICHLOROPHENYLACETONTRILE 2,6-Dichloropenzyl Acetonitrile 2,6-Dichlorophenylacetonitrile,97% 2,6-DICHLOROPHENYLACETONITRILE, 99+% Benzeneacetonitrile, 2,6-dichloro- 6-Dichlorophenylacetontrile 2,6-DichlorobenzylCyanide> Guanfacine Impurity 13 2,6-DICHLOROPHENYLACETONITRILE 3215-64-3 3125-64-3 C8H5Cl2N ARYL ISOCYANATE Organic Building Blocks Nitrogen Compounds Cyanides/Nitriles C8 to C9 Building Blocks FINE Chemical & INTERMEDIATES Aromatic Nitriles Nitrile
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