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ChemicalBook >> CAS DataBase List >>4-Pyrimidinamine, 2-methyl- (9CI)

4-Pyrimidinamine, 2-methyl- (9CI)

CAS No.
74-69-1
Chemical Name:
4-Pyrimidinamine, 2-methyl- (9CI)
Synonyms
2-methylpyrimidin-4-amine;2-Methyl-4-pyrimidinamine;184573;PKR-00635;4-PyriMidinaMine,2-Methyl;4-Amino-2-methylpyrimidine;2-Methylpyrimidin-4-amine 98%;4-Pyrimidinamine, 2-methyl- (9CI);2-Methyl-4-Pyrimidinamine(WX606010);2-methyl-1,4-dihydropyrimidin-4-imine
CBNumber:
CB41081857
Molecular Formula:
C5H7N3
Molecular Weight:
109.13
MDL Number:
MFCD00626295
MOL File:
74-69-1.mol
MSDS File:
SDS
Last updated:2026-05-28 02:25:52
Product description Number Pack Size Price
4-Amino-2-methylpyrimidine Asreported 260404 2g $1574
4-Amino-2-methylpyrimidine Asreported 260404 5g $3292
4-Amino-2-methylpyrimidine Asreported 260404 10g $5706
2-Methylpyrimidin-4-amine 98% OR301238 100mg $21
2-Methylpyrimidin-4-amine 98% OR301238 250mg $24
More product size

4-Pyrimidinamine, 2-methyl- (9CI) Properties

Melting point 204-205℃
Boiling point 222℃
Density 1.155
Flash point 111℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 5.99±0.10(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C5H7N3/c1-4-7-3-2-5(6)8-4/h2-3H,1H3,(H2,6,7,8)
InChIKey GKVDLTTVBNOGNJ-UHFFFAOYSA-N
SMILES C1(C)=NC=CC(N)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  26-39
HS Code  2933599590

4-Pyrimidinamine, 2-methyl- (9CI) price More Price(89)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 260404 4-Amino-2-methylpyrimidine Asreported 74-69-1 2g $1574 2026-06-03 Buy
Usbiological 260404 4-Amino-2-methylpyrimidine Asreported 74-69-1 5g $3292 2026-06-03 Buy
Usbiological 260404 4-Amino-2-methylpyrimidine Asreported 74-69-1 10g $5706 2026-06-03 Buy
Apolloscientific OR301238 2-Methylpyrimidin-4-amine 98% 74-69-1 100mg $21 2026-06-04 Buy
Apolloscientific OR301238 2-Methylpyrimidin-4-amine 98% 74-69-1 250mg $24 2026-06-04 Buy
Product number Packaging Price Buy
260404 2g $1574 Buy
260404 5g $3292 Buy
260404 10g $5706 Buy
OR301238 100mg $21 Buy
OR301238 250mg $24 Buy

4-Pyrimidinamine, 2-methyl- (9CI) Chemical Properties,Uses,Production

Synthesis Reference(s)

Tetrahedron Letters, 7, p. 4325, 1966 DOI: 10.1016/0005-2760(66)90119-6

Synthesis

Trimethyl orthoacetate

1445-45-0

3-Methoxyacrylonitrile

60838-50-8

4-Pyrimidinamine, 2-methyl- (9CI)

74-69-1

The general procedure for the synthesis of 2-methyl-4-aminopyrimidine from trimethyl orthoacetate and 3-methoxyacrylonitrile was as follows: in a 10 mL stainless steel pressure-resistant reactor, 1.0 g (12 mmol) of 3-methoxyacrylonitrile, 3.9 g (32 mmol) of trimethyl orthoacetate, and 4.0 g (56 mmol) of 24 wt% ammonia-methanol solution were added in sequence. The reaction mixture was stirred at 130°C for 8 hours. After completion of the reaction, 20 mL of hexane was added to the reaction mixture, stirred thoroughly and filtered to afford 0.94 g (isolated yield: 72%) of the target product 2-methyl-4-aminopyrimidine as yellow crystals. 2-methyl-4-aminopyrimidine was characterized physically as follows: 1H-NMR (DMSO-d6, δ/ppm): 2.29 (3H, s), 6.22 (1H, dd, J = 5.9), 4.0 g (56 mmol) of 24 wt% ammonia-methanol solution. dd, J = 5.9, 0.5 Hz), 6.69 (2H, brs), 7.94 (1H, d, J = 5.9 Hz); CI-MS (m/e): 109 (M + 1).

References

[1] Patent: US2008/45712, 2008, A1. Location in patent: Page/Page column 3-4

1445-45-0
60838-50-8
74-69-1
Synthesis of 4-Pyrimidinamine, 2-methyl- (9CI) from Trimethyl orthoacetate and 3-Methoxyacrylonitrile
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View Lastest Price from 4-Pyrimidinamine, 2-methyl- (9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Pyrimidinamine, 2-methyl- (9CI)  pictures 2025-11-18 4-Pyrimidinamine, 2-methyl- (9CI)
74-69-1
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Methyl-4-pyrimidinamine pictures 2022-02-19 2-Methyl-4-pyrimidinamine
74-69-1
1KG 99.1% 100 tons Honest Joy Holdings Limited
4-Pyrimidinamine, 2-methyl- (9CI) pictures 2020-01-03 4-Pyrimidinamine, 2-methyl- (9CI)
74-69-1
$1.00 1KG 95-99% 1ton Career Henan Chemical Co

4-Pyrimidinamine, 2-methyl- (9CI) Spectrum

4-Pyrimidinamine, 2-methyl- (9CI) 4-Amino-2-methylpyrimidine 4-PyriMidinaMine,2-Methyl 2-Methylpyrimidin-4-amine 98% 184573 2-Methyl-4-Pyrimidinamine(WX606010) PKR-00635 4-Pyrimidinamine, 2-methyl- (9CI) ISO 9001:2015 REACH 2-methyl-1,4-dihydropyrimidin-4-imine 2-methylpyrimidin-4-amine 2-Methyl-4-pyrimidinamine 74-69-1 76-69-1 PYRIMIDINE
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