Methyl-5-amino-2-chlorobenzoate
- CAS No.
- 42122-75-8
- Chemical Name:
- Methyl-5-amino-2-chlorobenzoate
- Synonyms
- TIMTEC-BB SBB013130;OTAVA-BB 7020693933;METHYL 2-CHLORO-5-AMINOBENZOATE;Methyl 3-amino-6-chlorobenzoate;Methyl-5-amino-2-chlorobenzoate;Methyl 2-chloro-5-aminobenzoate 95+%;5-Amino-2-chlorobenzoic acid methyl ester;2-Chloro-5-aMinobenzoic acid Methyl ester;BENZOIC ACID, 5-AMINO-2-CHLORO-, METHYL ESTER;methyl 5-amino-2-chlorobenzoate(SALTDATA: HCl)
- CBNumber:
- CB41115000
- Molecular Formula:
- C8H8ClNO2
- Molecular Weight:
- 185.61
- MDL Number:
- MFCD07800315
- MOL File:
- 42122-75-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 5-Amino-2-chlorobenzoate >98.0%(T) | M2812 | 1g | $23 |
| Methyl 5-Amino-2-chlorobenzoate >98.0%(T) | M2812 | 5g | $69 |
| Methyl 5-amino-2-chlorobenzoate Asreported | 283255 | 1g | $360 |
| Methyl 5-amino-2-chlorobenzoate Asreported | 283255 | 2g | $516 |
| Methyl 5-amino-2-chlorobenzoate Asreported | 283255 | 5g | $758 |
| More product size | |||
| Melting point | 68-70℃ |
|---|---|
| Boiling point | 320℃ |
| Density | 1.311 |
| Flash point | 147℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | soluble in Methanol |
| form | powder to lump |
| pka | 2.81±0.10(Predicted) |
| color | White to Yellow to Orange |
| InChI | InChI=1S/C8H8ClNO2/c1-12-8(11)6-4-5(10)2-3-7(6)9/h2-4H,10H2,1H3 |
| InChIKey | LBNPBOFVHYOPIB-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC(N)=CC=C1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| HS Code | 2916399090 | |||||||||
| NFPA 704 |
|
Methyl-5-amino-2-chlorobenzoate price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2812 | Methyl 5-Amino-2-chlorobenzoate >98.0%(T) | 42122-75-8 | 1g | $23 | 2026-04-30 | Buy |
| TCI Chemical | M2812 | Methyl 5-Amino-2-chlorobenzoate >98.0%(T) | 42122-75-8 | 5g | $69 | 2026-04-30 | Buy |
| Usbiological | 283255 | Methyl 5-amino-2-chlorobenzoate Asreported | 42122-75-8 | 1g | $360 | 2026-06-03 | Buy |
| Usbiological | 283255 | Methyl 5-amino-2-chlorobenzoate Asreported | 42122-75-8 | 2g | $516 | 2026-06-03 | Buy |
| Usbiological | 283255 | Methyl 5-amino-2-chlorobenzoate Asreported | 42122-75-8 | 5g | $758 | 2026-06-03 | Buy |
Methyl-5-amino-2-chlorobenzoate Chemical Properties,Uses,Production
Chemical Properties
Pale yellow crystal
Uses
Methyl 5-amino-2-chlorobenzoate
Synthesis
67-56-1
89-54-3
42122-75-8
The general procedure for the synthesis of methyl 2-chloro-5-aminobenzoate from methanol and 5-amino-2-chlorobenzoic acid was as follows: to a stirred solution of 5-amino-2-chlorobenzoic acid (50 g, 291 mmol) in methanol (300 mL) was added chloromethane (45 mL, 605 mmol) dropwise at 0 °C. The reaction mixture was refluxed for 12 hours and then cooled to room temperature. Subsequently, the reaction mixture was concentrated under vacuum and the residue was dissolved in ethyl acetate (500 mL), washed with saturated aqueous sodium bicarbonate (3 x 100 mL), dried over anhydrous sodium sulfate and concentrated again under vacuum to give methyl 5-amino-2-chlorobenzoate as a light white solid (54 g, quantitative yield).LC/MS analysis: m/e Calculated value C8H8ClNO2 (M +H)+: 186.61, measured value: 185.9.
References
[1] Patent: WO2011/128251, 2011, A1. Location in patent: Page/Page column 180-181
[2] Patent: US2011/257151, 2011, A1. Location in patent: Page/Page column 67
[3] Patent: WO2007/60026, 2007, A1. Location in patent: Page/Page column 48-49
[4] Patent: EP1746099, 2007, A1. Location in patent: Page/Page column 18-19
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 8, p. 2465 - 2481
Methyl-5-amino-2-chlorobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| CD Chemical Group Limited | +86-13651442114 | info@codchem.com | China | 17259 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
View Lastest Price from Methyl-5-amino-2-chlorobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-12 | Methyl-5-amino-2-chlorobenzoate
42122-75-8
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Methyl-5-amino-2-chlorobenzoate
42122-75-8
- $1.00
- 99%
- Career Henan Chemical Co
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