2-Bromo-6-chloropyridin-3-amine
- CAS No.
- 1050501-88-6
- Chemical Name:
- 2-Bromo-6-chloropyridin-3-amine
- Synonyms
- 2-Bromo-6-chloro-3-pyridinamine;2-Bromo-6-chloropyridin-3-amine;2-bromo-3-amino-6-chloropyridine;3-AMINO-6-CHLORO-2-BROMOPYRIDINE;3-Amino-2-bromo-6-chloropyridine;3-Pyridinamine, 2-bromo-6-chloro-;2-Bromo-6-chloro-pyridin-3-ylamine;2-Bromo-6-chloropyridin-3-amine ISO 9001：2015 REACH
- CBNumber:
- CB41503175
- Molecular Formula:
- C5H4BrClN2
- Molecular Weight:
- 207.46
- MDL Number:
- MFCD11504927
- MOL File:
- 1050501-88-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Amino-2-bromo-6-chloropyridine | 231534 | 1g | $215 |
| 3-Amino-2-bromo-6-chloropyridine | 231534 | 5g | $435 |
| 3-Amino-2-bromo-6-chloropyridine | 231534 | 25g | $1231 |
| 3-Amino-2-bromo-6-chloropyridine | FA55774 | 5g | $250 |
| 3-Amino-2-bromo-6-chloropyridine | FA55774 | 2g | $250 |
| Boiling point | 330.3±37.0 °C(Predicted) |
|---|---|
| Density | 1.834 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | -0.12±0.10(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C5H4BrClN2/c6-5-3(8)1-2-4(7)9-5/h1-2H,8H2 |
| InChIKey | OPKKXWUGXHSFQI-UHFFFAOYSA-N |
| SMILES | C1C=C(N)C(Br)=NC=1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
2-Bromo-6-chloropyridin-3-amine price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 231534 | 3-Amino-2-bromo-6-chloropyridine | 1050501-88-6 | 1g | $215 | 2026-06-03 | Buy |
| Usbiological | 231534 | 3-Amino-2-bromo-6-chloropyridine | 1050501-88-6 | 5g | $435 | 2026-06-03 | Buy |
| Usbiological | 231534 | 3-Amino-2-bromo-6-chloropyridine | 1050501-88-6 | 25g | $1231 | 2026-06-03 | Buy |
| Biosynth | FA55774 | 3-Amino-2-bromo-6-chloropyridine | 1050501-88-6 | 5g | $250 | 2026-06-04 | Buy |
| Biosynth | FA55774 | 3-Amino-2-bromo-6-chloropyridine | 1050501-88-6 | 2g | $250 | 2026-06-04 | Buy |
2-Bromo-6-chloropyridin-3-amine Chemical Properties,Uses,Production
Uses
2-Bromo-6-chloro-3-pyridinamine is a reactant used in the synthesis of kilogram quantities of an akt Kinase inhibitor. It is mainly used as starting material for the production of many pharmaceutical compounds.
Synthesis
5350-93-6
1050501-88-6
Step 1: Synthesis of 2-bromo-6-chloropyridin-3-amine Bromine (24.86 g, 155.57 mmol) was slowly added to a solution of acetic acid (383 mL) containing 6-chloropyridin-3-amine (20.00 g, 155.57 mmol) and sodium acetate (25.52 g, 311.14 mmol). The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the acetic acid was removed by rotary evaporator. The residue was dissolved in ethyl acetate (EtOAc) and washed sequentially with saturated aqueous sodium carbonate (Na2CO3) solution, water and brine. The organic layer was dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to afford the target product 2-bromo-6-chloropyridin-3-amine (32.20 g, 99.8% yield). Mass spectrometry analysis showed m/z = 206.96 ([M+H]+), which is consistent with the isotopic distribution pattern of Cl and Br.
References
[1] Patent: WO2012/80450, 2012, A1. Location in patent: Page/Page column 25
[2] Patent: WO2013/186335, 2013, A1. Location in patent: Page/Page column 87
[3] Patent: WO2013/186333, 2013, A1. Location in patent: Page/Page column 102
[4] Patent: WO2014/60411, 2014, A1. Location in patent: Page/Page column 56
[5] Patent: US2015/111868, 2015, A1. Location in patent: Paragraph 0856; 0857
2-Bromo-6-chloropyridin-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-6-chloropyridin-3-amine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28509 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from 2-Bromo-6-chloropyridin-3-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 2-Bromo-6-chloropyridin-3-amine
1050501-88-6
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-04-04 | 2-Bromo-6-chloropyridin-3-amine
1050501-88-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Bromo-6-chloropyridin-3-amine
1050501-88-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Bromo-6-chloropyridin-3-amine
1050501-88-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
