7-Bromo-2,3-dihydro-isoindol-1-one
- CAS No.
- 200049-46-3
- Chemical Name:
- 7-Bromo-2,3-dihydro-isoindol-1-one
- Synonyms
- 7-Bromo-1-isoindolinone;7-Bromo-2,3-dihydro-isoindol-1-one;7-bromo-2,3-dihydro-isoindole-1-one;7-broMo-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one, 7-broMo-2,3-dihydro-
- CBNumber:
- CB41874736
- Molecular Formula:
- C8H6BrNO
- Molecular Weight:
- 212.04
- MDL Number:
- MFCD11848600
- MOL File:
- 200049-46-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | AS59665 | 1g | $59 |
| 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | AS59665 | 5g | $271 |
| 7-Bromo-2,3-dihydro-1H-isoindol-1-one 95% | OR305302 | 250mg | $24 |
| 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | AS59665 | 25g | $1178 |
| 7-Bromo-2,3-dihydro-1H-isoindol-1-one 95% | OR305302 | 1g | $83 |
| More product size | |||
| Boiling point | 452.2±45.0 °C(Predicted) |
|---|---|
| Density | 1.666±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 13.36±0.20(Predicted) |
| form | powder |
| color | Off-white |
| InChI | InChI=1S/C8H6BrNO/c9-6-3-1-2-5-4-10-8(11)7(5)6/h1-3H,4H2,(H,10,11) |
| InChIKey | XTWPGJGLJLJZHW-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2Br)CN1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P362+P364 |
| HS Code | 2925199590 |
7-Bromo-2,3-dihydro-isoindol-1-one price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS59665 | 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | 200049-46-3 | 1g | $59 | 2026-06-04 | Buy |
| Activate Scientific | AS59665 | 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | 200049-46-3 | 5g | $271 | 2026-06-04 | Buy |
| Apolloscientific | OR305302 | 7-Bromo-2,3-dihydro-1H-isoindol-1-one 95% | 200049-46-3 | 250mg | $24 | 2026-06-04 | Buy |
| Activate Scientific | AS59665 | 7-Bromo-2,3-dihydro-1H-isoindol-1-one 97% | 200049-46-3 | 25g | $1178 | 2026-06-04 | Buy |
| Apolloscientific | OR305302 | 7-Bromo-2,3-dihydro-1H-isoindol-1-one 95% | 200049-46-3 | 1g | $83 | 2026-06-04 | Buy |
7-Bromo-2,3-dihydro-isoindol-1-one Chemical Properties,Uses,Production
Uses
7-Bromo-2,3-dihydro-isoindole-1-one is a useful research chemical for organic synthesis and other chemical processes.
Synthesis
99548-56-8
200049-46-3
General procedure for the synthesis of 7-bromo-2,3-dihydro-isoindol-1-one from methyl 2-bromo-6-methylbenzoate: methyl 2-bromo-6-methylbenzoate (65.9 g, 288 mmol), N-bromosuccinimide (NBS, 53.8 g, 302 mmol), and azobisisobutyronitrile (AIBN, 2.3 g, 14 mmol) were dissolved in benzene ( 1 L) in benzene and heated to reflux for 8 hours. After completion of the reaction, the mixture was cooled to 25 °C, the succinimide was removed by filtration and the filter cake was washed with hexane. The filtrate was concentrated and dissolved in tetrahydrofuran (THF, 1 L), concentrated ammonia (NH4OH, 290 mL) was added, and stirred at 25 °C for 4 hours. The reaction solution was diluted with water (1 L) and extracted with ethyl acetate (EtOAc, 3 x 300 mL). The organic phases were combined, concentrated and purified by silica gel column chromatography (SiO2) to afford 7-bromo-2,3-dihydro-isoindol-1-one (28.9 g, 47% yield) as an off-white solid. 1H NMR (400 MHz, CDCl3) δ 7.73 (br s, 1H), 7.62 (d, J = 7.2 Hz, 1H), 7.43 (m, 2H),. 4.42 (s, 2H); mass spectrum (ESI) m/z: not detected (MH+).
References
[1] Patent: WO2007/47646, 2007, A2. Location in patent: Page/Page column 52-53
[2] Heterocycles, 1997, vol. 45, # 11, p. 2217 - 2221
7-Bromo-2,3-dihydro-isoindol-1-one Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10457 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19987 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49895 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33324 | 58 |
200049-46-3(7-Bromo-2,3-dihydro-isoindol-1-one)Related Search:
1of4
