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(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER structure

CAS No.: 344331-90-4

Chemical Name:: (6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER

Synonyms: tert-butyl N-(6-bromopyridin-2-yl)carbamate;Cholest-5-en-3-ol,(7α)-;2-(BOC-AMino)-6-broMopyridine;N-Boc-2-AMino-6-broMopyridine;6-BROMO-2-(N-BOC AMINO) PYRIDNE;tert-Butyl 6-bromopyridin-2-ylcarbamate;t-butyl N-(6-bromo-2-pyridinyl)carbamate;6-BROMO-2-TERT-BUTOXYCARBONYLAMINO-PYRIDINE;Benzenemethanesulfonylchloride,9-(trifluoromethyl)-;(6-BroMo-pyridin-2-yl)-carbaMic acid tert-butyl ester

CBNumber:: CB4218474

Molecular Formula:: C10H13BrN2O2

Molecular Weight:: 273.13

MDL Number:: MFCD07367929

MOL File:: 344331-90-4.mol

MSDS File:: SDS

Last updated:2026-05-28 02:25:15

Product description	Number	Pack Size	Price
2-(Boc-Amino)-6-bromopyridine >99%	OR959588	1g	$21
2-(Boc-Amino)-6-bromopyridine >99%	OR959588	5g	$88
2-(Boc-Amino)-6-bromopyridine >99%	OR959588	25g	$370
2-(Boc-Amino)-6-bromopyridine >99%	OR959588	100g	$1405
2-(Boc-Amino)-6-bromopyridine >99%	OR959588	1g	$21
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(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER Properties

Boiling point	299.3±25.0 °C(Predicted)
Density	1.453±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	11.89±0.70(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933399990

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR959588	2-(Boc-Amino)-6-bromopyridine >99%	344331-90-4	1g	$21	2026-06-04	Buy
Apolloscientific	OR959588	2-(Boc-Amino)-6-bromopyridine >99%	344331-90-4	5g	$88	2026-06-04	Buy
Apolloscientific	OR959588	2-(Boc-Amino)-6-bromopyridine >99%	344331-90-4	25g	$370	2026-06-04	Buy
Apolloscientific	OR959588	2-(Boc-Amino)-6-bromopyridine >99%	344331-90-4	100g	$1405	2026-06-04	Buy
Apolloscientific	OR959588	2-(Boc-Amino)-6-bromopyridine >99%	344331-90-4	1g	$21	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR959588	1g	$21	Buy
OR959588	5g	$88	Buy
OR959588	25g	$370	Buy
OR959588	100g	$1405	Buy
OR959588	1g	$21	Buy

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER Chemical Properties,Uses,Production

Synthesis

19798-81-3

24424-99-5

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER

344331-90-4

Step 1. Synthesis of 6-bromo-2-Boc-aminopyridine: To a solution of dichloromethane (24 mL) containing 6-bromopyridin-2-amine (3 g, 17.34 mmol), triethylamine (3.14 mL, 22.54 mmol), and DMAP (0.424 g, 3.47 mmol) was slowly added a solution of dichloromethane (6 mL) containing di-tert-butyl dicarbonate (4.83 mL, 20.81 mmol). 20.81 mmol) to a solution of dichloromethane (6 mL). The reaction mixture was stirred at room temperature for about 24 hours. Upon completion of the reaction, the reaction mixture was diluted with water, saturated saline and ethyl acetate. The aqueous layer was separated and extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography to give 6-bromo-2-tert-butoxycarbonylaminopyridine as a white solid. Yield: 1.67 g. LCMS (m/z): 274.9 [M+H]+; Retention time: 0.54 min (major peak), 0.95 min.

References

[1] Patent: WO2012/101066, 2012, A1. Location in patent: Page/Page column 77
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 24, p. 8709 - 8715
[3] Patent: WO2017/205536, 2017, A2. Location in patent: Page/Page column 193; 194
[4] Patent: WO2004/113331, 2004, A1. Location in patent: Page 68
[5] Patent: WO2006/53791, 2006, A2. Location in patent: Page/Page column 39-40

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER synthesis

Synthesis of (6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER from 2-Amino-6-bromopyridine and Di-tert-butyl dicarbonate

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER Preparation Products And Raw materials

Raw materials

Ammonium hydroxide 2,6-Dibromopyridine Acetic anhydride 6-(DI-BOC-AMINO)-2-BROMOPYRIDINE 2-Amino-6-bromopyridine

tert-Butanol Di-tert-butyl dicarbonate 6-Bromopicolinic acid Carbonic acid, bis(1,1-dimethylethyl) ester PHOSGENE

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Preparation Products

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER Suppliers

Global( 107)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30225	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49969	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4871	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
Alchem Pharmtech,Inc.	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
Sichuan Biosynce Pharmatech Co., Ltd.	58
Aladdin Scientific	58

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER Spectrum

(6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER(344331-90-4)¹HNMR

344331-90-4((6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER)Related Search:

Carbamic acid, N-(4-bromo-2,6-difluorophenyl)-, 1,1-dimethylethyl ester Tert-butyl (4-bromo-2,3-dimethylphenyl)carbamate 4-CHLORO-(N-BOC)ANILINE 97 (4-Bromo-2-fluoro-5-methyl-phenyl)-carbamic acid tert-butyl ester N-BOC-4-broMo-3-Methylaniline

2-BOC-AMINO-4-BROMOTOLUENE Carbamic acid, N-(4-bromo-2,5-difluorophenyl)-, 1,1-dimethylethyl ester (5-BROMO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER N-(3-Iodo-5-methylpyridin-2-yl)pivalamide tert-Butyl (2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)biscarbamate

tert-Butyl[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin -2-yl]carbamate (2-Bromo-5-methyl-phenyl)-carbamic acid tert-butyl ester CARBAMIC ACID, (5-BROMO-4-METHYL-2-PYRIDINYL)-,1,1-DIMETHYLETHYL ESTER TERT-BUTYL 4-BROMO-2-CHLOROPHENYLCARBAMATE Carbamic acid, (3-chloro-4-fluorophenyl)-, 1,1-dimethylethyl ester

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6-BROMO-2-TERT-BUTOXYCARBONYLAMINO-PYRIDINE (6-BROMO-2-PYRIDINYL)-CARBAMIC ACID,1,1-DIMETHYLETHYL ESTER N-Boc-2-AMino-6-broMopyridine Carbamic acid,N-(6-bromo-2-pyridinyl)-,1,1-dimethylethyl ester tert-Butyl 6-bromopyridin-2-ylcarbamate t-butyl N-(6-bromo-2-pyridinyl)carbamate (6-BroMo-pyridin-2-yl)-carbaMic acid tert-butyl ester 2-(BOC-AMino)-6-broMopyridine Cholest-5-en-3-ol,(7α)- Benzenemethanesulfonylchloride,9-(trifluoromethyl)- 6-BROMO-2-(N-BOC AMINO) PYRIDNE tert-butyl N-(6-bromopyridin-2-yl)carbamate 344331-90-4 pharmacetical

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