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ChemicalBook >> CAS DataBase List >>D-(-)-3-Acetylthio-2-methylpropionic acid

D-(-)-3-Acetylthio-2-methylpropionic acid

CAS No.
76497-39-7
Chemical Name:
D-(-)-3-Acetylthio-2-methylpropionic acid
Synonyms
Captopril Impurity K;Captopril Impurity V;Captopril Impurity 7;Captopril EP Impurity G (S-Isomer);(2S)-3-(Acetylthio)-2-methylpropano;(S)-β-(Acetylmercapto)isobutyric acid;(S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID;D-(-)-3-Acetylthio-2-Methylpropionic A;Captopril Impurity G as (S)-enantiomer;D-3-(Acetylthio)-2-methylpropanoic acid
CBNumber:
CB4240644
Molecular Formula:
C6H10O3S
Molecular Weight:
162.21
MDL Number:
MFCD00038563
MOL File:
76497-39-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:13:16
Product description Number Pack Size Price
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid >98.0%(T) A1334 5mL $74
(S)-(-)-3-(Acetylthio)-2-methylpropionic Acid >98.0%(T) A1334 25mL $220
S-(-)-3-(Acetylthio)-2-methylpropionic acid 99+% ee (GC) ≥99%ee(GC) 241761 1g $159
S-(-)-3-(Acetylthio)-2-methylpropionic acid 99+% ee (GC) ≥99%ee(GC) 241761 5g $207
D(-)S-Acetyl-beta-mercapto isobutyric acid Asreported 260661 10g $382
More product size

D-(-)-3-Acetylthio-2-methylpropionic acid Properties

Melting point 5 °C
Boiling point 120-132 °C (1 mmHg)
alpha -46 º (c=1, 96% EtOH)
Density 1.178 g/mL at 20 °C(lit.)
refractive index n20/D 1.490
Flash point >230 °F
storage temp. Store at 0-5°C
solubility Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form liquid
pka 4.22±0.10(Predicted)
Water Solubility INSOLUBLE
InChI InChI=1S/C6H10O3S/c1-4(6(8)9)3-10-5(2)7/h4H,3H2,1-2H3,(H,8,9)/t4-/m1/s1
InChIKey VFVHNRJEYQGRGE-SCSAIBSYSA-N
SMILES C(O)(=O)[C@H](C)CSC(C)=O
CAS DataBase Reference 76497-39-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  C,T
Risk Statements  34-36-24/25
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
HS Code  29309070
REACH Registrations Active
NFPA 704
1
2 0

D-(-)-3-Acetylthio-2-methylpropionic acid price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1334 (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid >98.0%(T) 76497-39-7 5mL $74 2021-12-16 Buy
TCI Chemical A1334 (S)-(-)-3-(Acetylthio)-2-methylpropionic Acid >98.0%(T) 76497-39-7 25mL $220 2021-12-16 Buy
Usbiological 241761 S-(-)-3-(Acetylthio)-2-methylpropionic acid 99+% ee (GC) ≥99%ee(GC) 76497-39-7 1g $159 2026-06-03 Buy
Usbiological 241761 S-(-)-3-(Acetylthio)-2-methylpropionic acid 99+% ee (GC) ≥99%ee(GC) 76497-39-7 5g $207 2026-06-03 Buy
Usbiological 260661 D(-)S-Acetyl-beta-mercapto isobutyric acid Asreported 76497-39-7 10g $382 2026-06-03 Buy
Product number Packaging Price Buy
A1334 5mL $74 Buy
A1334 25mL $220 Buy
241761 1g $159 Buy
241761 5g $207 Buy
260661 10g $382 Buy

D-(-)-3-Acetylthio-2-methylpropionic acid Chemical Properties,Uses,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

S-Acetylthio-2-methylpropionic acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.

Uses

ACE-inhibitors.

33325-40-5
76497-39-7
Synthesis of D-(-)-3-Acetylthio-2-methylpropionic acid from 3-Acetylthio-2-methylpropanoic acid
Global( 151)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 24597 58

View Lastest Price from D-(-)-3-Acetylthio-2-methylpropionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Captopril EP Impurity G pictures 2025-12-16 Captopril EP Impurity G
76497-39-7
10mg 98 10000000 Moxin Chemicals
D-(-)-3-Acetylthio-2-methylpropionic acid pictures 2019-07-06 D-(-)-3-Acetylthio-2-methylpropionic acid
76497-39-7
$1.00 1G 98% 100KG Career Henan Chemical Co
D(-)S-ACETYL-BETA-MERCAPTO ISOBUTYRIC ACID D-(S)-3-ACETYL-3-MERCAPTO-2-METHYL PROPANOIC ACID D-(-)-3-ACETYLSULFANYL-2-METHYLPROPIONIC ACID d-(-)-3-acetylthio-2-methylpropionic acid (S)-β-(Acetylmercapto)isobutyric acid D-3-(Acetylthio)-2-methylpropanoic acid D-(S)-3-Acetylthio-2-methylpropionic acid (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONI& (-)-3-(Acetylthio)-2-methylpropanoic acid (Captopril Intermediate) (S)-BETA-(ACETYLMERCAPTO)ISOBUTYRIC ACID (S)-(-)-BETA-ACETYLTHIO-2-METHYLPROPIONIC ACID (S)-(-)-3-(ACETYLMERCAPTO)ISOBUTYRIC ACID (S)-(-)-3-ACETYLTHIO-2-METHYLPROPANOIC ACID (S)-(-)-3-(ACETYLTHIO)-2-METHYLPROPIONIC ACID (S)-(-)-3-(ACETYLTHIO)ISOBUTYRIC ACID (S)-ACETYL-3-MERCAPTO-2-METHYLPROPANOIC ACID (S)-(-)-ACETYLTHIO 2-METHYLPROPIONIC ACID (S)-β-(Acetylmercapto)isobutyric acid, D-(-)-S-Acetyl-β-mercaptoisobutyric acid Propanoic acid, 3-(acetylthio)-2-methyl-, (2S)- (2S)-3-Acetylsulfanyl-2-methylpropanoate (2S)-2-Methyl-3-(acetylthio)propionic acid (S)-2-Methyl-3-(acetylthio)propionic acid D(-)-S-Acetyl-beta-mercaptoisobutyric acid,99% (S)-3-Acetylsulfanyl-2-Methylpropionic Acid D-(-)-3-Acetylthio-2-Methylpropionic A (2S)-3-(Acetylsulphanyl)-2-methylpropanoic acid, (2S)-3-(Acetylthio)-2-methylpropionic acid Captopril Impurity K (2S)-3-acetylthio-2-methylpropionic acid, D-(-)-S-3-acetylthio-2-methylpropanoic acid, (2S)-3-Acetylthio-2-methylpropanoic acid, (S)-3-(acetylthio)isobutyric acid, (S)-(-)-acetyl-β-mercaptoisobutyric acid, D-(-)-S-acetyl-β-mercaptoisobutyric acid, (S)-3-acetylsulfanyl-2-methyl-propionic acid (S)-(-)-3-(Acetylthio)-2-methylpropionic acid≥ 99% ee (GC) Captopril EP Impurity G (S-Isomer) Captopril Impurity V (2S)-3-acetylthio-2-methylpropionic acid (2S)-3-(Acetylthio)-2-methylpropano Captopril Impurity 7 Captopril EP Impurity G as (S)-enantiomer Captopril Impurity G as (S)-enantiomer 76497-39-7 79497-39-7 C6H10O3S Carboxylic Acids (Chiral) Chiral Building Blocks Asymmetric Synthesis Organic Building Blocks Thiocarbonyl Compounds Carboxylic Acids (Chiral) Chiral Building Blocks Synthetic Organic Chemistry
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