Methyl 2-(broMoMethyl)nicotinate
- CAS No.
- 116986-08-4
- Chemical Name:
- Methyl 2-(broMoMethyl)nicotinate
- Synonyms
- Methyl 2-(broMoMethyl)nicotinate;METHYL 2-(BROMOMETHYL)PYRIDINE-3-CARBOXYLATE;3-Pyridinecarboxylic acid, 2-(broMoMethyl)-, Methyl ester
- CBNumber:
- CB42732882
- Molecular Formula:
- C8H8BrNO2
- Molecular Weight:
- 230.06
- MDL Number:
- MOL File:
- 116986-08-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 2-(bromomethyl)nicotinate 90+% | M37745 | 100mg | $27 |
| Methyl 2-(bromomethyl)nicotinate 90+% | M37745 | 250mg | $50 |
| Methyl 2-(bromomethyl)nicotinate 90+% | M37745 | 1g | $180 |
| Methyl 2-(bromomethyl)nicotinate 90+% | M37745 | 50mg | $220 |
| Methyl 2-(bromomethyl)nicotinate 97.00% | X195617 | 1G | $175 |
| More product size | |||
Methyl 2-(broMoMethyl)nicotinate price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | M37745 | Methyl 2-(bromomethyl)nicotinate 90+% | 116986-08-4 | 100mg | $27 | 2026-05-06 | Buy |
| Synthonix | M37745 | Methyl 2-(bromomethyl)nicotinate 90+% | 116986-08-4 | 250mg | $50 | 2026-05-06 | Buy |
| Synthonix | M37745 | Methyl 2-(bromomethyl)nicotinate 90+% | 116986-08-4 | 1g | $180 | 2026-05-06 | Buy |
| Synthonix | M37745 | Methyl 2-(bromomethyl)nicotinate 90+% | 116986-08-4 | 50mg | $220 | 2026-05-06 | Buy |
| ACHEMBLOCK | X195617 | Methyl 2-(bromomethyl)nicotinate 97.00% | 116986-08-4 | 1G | $175 | 2026-05-27 | Buy |
Methyl 2-(broMoMethyl)nicotinate Chemical Properties,Uses,Production
Synthesis
65719-09-7
116986-08-4
General procedure for the synthesis of methyl 2-(bromomethyl)nicotinate from methyl 2-methylnicotinate: methyl 2-methylnicotinate (4.1 g, 27.1 mmol), N-bromosuccinimide (NBS, 5.8 g, 32.5 mmol) and azobisisobutyronitrile (AIBN, 100 mg, 0.61 mmol) were dissolved in carbon tetrachloride (55 mL). The reaction mixture was stirred at 90 °C for 16 h under nitrogen protection. Upon completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with water (25 mL), followed by extraction of the aqueous layer with dichloromethane (50 mL x 3). The organic layers were combined and concentrated under reduced pressure to remove the solvent, and the resulting crude product was purified by silica gel column chromatography to afford the target product methyl 2-(bromomethyl)nicotinate (5.0 g, 80.6% yield). The product was analyzed by LCMS, m/z: 229.9 ([M+H]+).
References
[1] Patent: WO2015/200677, 2015, A2. Location in patent: Paragraph 00522; 00523
[2] Tetrahedron Letters, 1981, vol. 22, # 50, p. 5097 - 5100
[3] Journal fuer Praktische Chemie (Leipzig), 1987, vol. 329, # 4, p. 557 - 562
[4] Patent: WO2012/61169, 2012, A1. Location in patent: Page/Page column 49
Methyl 2-(broMoMethyl)nicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Hunan Jibang Biological Technology Co., LTD | +8613776644403 | sales02@kingboomtech.com | China | 1804 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Nanjing Moldeep Biochemical Co., Ltd. | +86-25-58282389 +8618913958656 | inquiries@moldeep.com | China | 19983 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Tianjin Derchemist Science & Technology Co., Ltd. | 22-58627059 13920586291 | zdcomcon@126.com | China | 4095 | 50 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 7970 | 58 |
| Shanghai Chenzhu Pharmaceutical Co., Ltd. | 13162380607 | 1696175688@qq.com | China | 824 | 55 |
