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4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER structure

CAS No.: 492431-11-5

Chemical Name:: 4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Synonyms: tert-Butyl 4-(6-chloropyridazin-3-yl)piperazine-1-carboxylate;Zinc02563759;1-Boc-4-(6-Chloropyridazin-3-yl);1-Boc-4-(6-chloropyridazin-3-yl)piperazine;1-Boc-4-(6-chloro-3-pyridazinyl)piperazine;1-N-Boc-4-(6-chloropyridazin-3-yl)piperazine;4-(6-Chloropyridazin-3-yl)piperazine, N1-BOC protected;4-(6-Chloropyridazin-3-yl)piperazine-1-carboxylic Acid t-Butyl Ester;4-(6-chloro-3-pyridazinyl)-1-piperazinecarboxylic acid tert-butyl ester;4-(6-Chloropyridazin-3-yl)piperazine-1-carboxylicacidtert-butylester95%

CBNumber:: CB4326962

Molecular Formula:: C13H19ClN4O2

Molecular Weight:: 298.77

MDL Number:: MFCD05864738

MOL File:: 492431-11-5.mol

MSDS File:: SDS

Last updated:2026-05-28 05:03:15

Product description	Number	Pack Size	Price
1-N-BOC-4-(6-CHLOROPYRIDAZIN-3-YL)PIPERAZINE 97%	30063	1G	$24
4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 98%	B121	1g	$16
4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 98%	B121	5g	$62
1-Boc-4-(6-Chloropyridazin-3-yl)piperazine 98%	B57149	250mg	$51
1-Boc-4-(6-Chloropyridazin-3-yl)piperazine 98%	B57149	1g	$57

Request For Quotation

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Properties

storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
Appearance	Light brown to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	30063	1-N-BOC-4-(6-CHLOROPYRIDAZIN-3-YL)PIPERAZINE 97%	492431-11-5	1G	$24	2026-04-30	Buy
AK Scientific	B121	4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 98%	492431-11-5	1g	$16	2026-06-04	Buy
AK Scientific	B121	4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 98%	492431-11-5	5g	$62	2026-06-04	Buy
Synthonix	B57149	1-Boc-4-(6-Chloropyridazin-3-yl)piperazine 98%	492431-11-5	250mg	$51	2026-05-06	Buy
Synthonix	B57149	1-Boc-4-(6-Chloropyridazin-3-yl)piperazine 98%	492431-11-5	1g	$57	2026-05-06	Buy

Product number	Packaging	Price	Buy
30063	1G	$24	Buy
B121	1g	$16	Buy
B121	5g	$62	Buy
B57149	250mg	$51	Buy
B57149	1g	$57	Buy

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties,Uses,Production

Uses

4-(6-Chloropyridazin-3-yl)piperazine-1-carboxylic Acid tert-Butyl Ester

Synthesis

141-30-0

57260-71-6

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

492431-11-5

To 3,6-dichloropyridazine (57.3 g, 385 mmol) and N-BOC-piperazine (71.6 g, 358 mmol) in 1,4-dioxane (250 mL) was added N,N-diisopropylethylamine (66.9 mL, 385 mmol). The reaction mixture was stirred at 80 °C overnight. Upon completion of the reaction, the mixture was concentrated under reduced pressure. The concentrated residue was dissolved in ethyl acetate (3 L) and washed sequentially with 10% citric acid solution, water and saturated saline. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by recrystallization from ethyl acetate to give tert-butyl 4-(6-chloropyridazin-3-yl)piperazine-1-carboxylate as an off-white solid (101 g, 88% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (ESI): 1H NMR δ 1.25 (9H, s), 3.26-3.47 (8H, m), 6.67 (1H, d, J = 9.6 Hz), 7.00 (1H, d, J = 9.6 Hz); MS (ESI) m/z: 299.0 [M + H]+.

References

[1] Patent: US2015/353542, 2015, A1. Location in patent: Paragraph 0539
[2] Patent: EP3305785, 2018, A1. Location in patent: Paragraph 0204; 0205
[3] Patent: WO2017/197051, 2017, A1. Location in patent: Page/Page column 299
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 11, p. 5361 - 5379
[5] Patent: US2005/176722, 2005, A1. Location in patent: Page/Page column 19

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

3,6-Dichloropyridazine 1-BOC-Piperazine 1,4-Dioxane N,N-Diisopropylethylamine

Preparation Products

1-Boc-4-(Pyridazin-3-yl)piperazine 3(2H)-Pyridazinone,6-(1-piperazinyl)-(9CI)

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Suppliers

Global( 71)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28232	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49962	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58

Supplier	Advantage
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from 4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 492431-11-5	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-12-20	4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 492431-11-5	$1.00	1KG	99%		Career Henan Chemical Co

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
492431-11-5
$1.10
99.00%
Dideu Industries Group Limited

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
492431-11-5
$1.00
99%
Career Henan Chemical Co

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Spectrum

4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(492431-11-5)¹HNMR

492431-11-5(4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER)Related Search:

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1-Boc-4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine 4-[(AMINOIMINOMETHYL)AMINO]-1-PIPERIDINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER MONOHYDROCHLORIDE 1-BOC-OCTAHYDRO-PYRROLO[3,4-B]PYRIDINE tert-butyl 4-hydroxy-2-oxopiperidine-1-carboxylate 1-Boc-4-chloro-3-formylindole

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3-CHLORO-6-(4-METHYL-1-PIPERAZINYL)PYRIDAZINE tert-Butyl 1-piperazinecarboxylate 1-(6-Chloropyridazino-3-yl)piperazine

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1-Boc-4-(6-chloropyridazin-3-yl)piperazine 4-(6-Chloropyridazin-3-yl)piperazine-1-carboxylic Acid t-Butyl Ester Zinc02563759 1-N-Boc-4-(6-chloropyridazin-3-yl)piperazine 1-Boc-4-(6-chloro-3-pyridazinyl)piperazine 1-Boc-4-(6-Chloropyridazin-3-yl) 4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(6-Chloropyridazin-3-yl)piperazine, N1-BOC protected 4-(6-CHLOROPYRIDAZIN-3-YL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95% 4-(6-Chloropyridazin-3-yl)piperazine-1-carboxylicacidtert-butylester95% 4-(6-chloro-3-pyridazinyl)-1-piperazinecarboxylic acid tert-butyl ester 1-Piperazinecarboxylic acid, 4-(6-chloro-3-pyridazinyl)-, 1,1-dimethylethyl ester 4-(6-CHLORO-PYRIDAZIN-3-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER ISO 9001：2015 REACH tert-Butyl 4-(6-chloropyridazin-3-yl)piperazine-1-carboxylate 492431-11-5 C13H19ClN4O2

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