2-Chloro-4-methylaniline
- CAS No.
- 615-65-6
- Chemical Name:
- 2-Chloro-4-methylaniline
- Synonyms
- oro-4-methyL;2-Chlor-4-toluidin;2-chloro-p-toluidin;2-chlor-4-toluidine;2-CHLORO-4-TOLUIDINE;2-CHLORO-P-TOLUIDINE;2-Chloro-4-methylani;p-Toluidine, 2-chloro-;4-AMINO-3-CHLOROTOLUENE;3-CHLORO-4-AMINOTOLUENE
- CBNumber:
- CB4349929
- Molecular Formula:
- C7H8ClN
- Molecular Weight:
- 141.6
- MDL Number:
- MFCD00007666
- MOL File:
- 615-65-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-4-methylaniline 98% | 125075 | 5g | $45.4 |
| 2-Chloro-4-methylaniline >98.0%(GC)(T) | A1437 | 5g | $33 |
| 2-Chloro-4-methylaniline >98.0%(GC)(T) | A1437 | 25g | $129 |
| 2-Chloro-4-methylaniline | 416798 | 1g | $319 |
| 2-Chloro-4-methylaniline | 416798 | 5g | $403 |
| More product size | |||
| Melting point | 7 °C (lit.) |
|---|---|
| Boiling point | 223-225 °C (lit.) |
| Density | 1.151 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 211 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | methanol: soluble |
| form | Liquid |
| pka | 3.09±0.10(Predicted) |
| color | Clear yellow to pale brown |
| BRN | 774514 |
| Stability | Acid Sensitive, Light Sensitive |
| InChI | 1S/C7H8ClN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3 |
| InChIKey | XGYLSRFSXKAYCR-UHFFFAOYSA-N |
| SMILES | Cc1ccc(N)c(Cl)c1 |
| CAS DataBase Reference | 615-65-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | K59ISJ2KO1 |
| NIST Chemistry Reference | Benzenamine, 2-chloro-4-methyl-(615-65-6) |
| EPA Substance Registry System | Benzenamine, 2-chloro-4-methyl- (615-65-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() ![]() GHS05,GHS06,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H319-H370-H372-H402-H302+H312+H332-H315-H318-H412-H302-H312-H331-H373 | |||||||||
| Precautionary statements | P304+P340-P501a-P260-P264-P270-P271-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P307+P311-P403+P233-P405-P501-P273-P280-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22-33 | |||||||||
| Safety Statements | 36/37-37/39-26-45-36/37/39 | |||||||||
| RIDADR | UN 2239 6.1/PG III (CHLOROTOLUIDINES, SOLID) | |||||||||
| RIDADR | UN 3429 6.1/PG III (CHLOROTOLUIDINES, LIQUID) | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XU5110000 | |||||||||
| F | 8-9-23 | |||||||||
| Hazard Note | Harmful | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214200 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Chronic 3 Eye Dam. 1 Skin Irrit. 2 |
|||||||||
| Hazardous Substances Data | 615-65-6(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
2-Chloro-4-methylaniline price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 125075 | 2-Chloro-4-methylaniline 98% | 615-65-6 | 5g | $45.4 | 2023-01-07 | Buy |
| TCI Chemical | A1437 | 2-Chloro-4-methylaniline >98.0%(GC)(T) | 615-65-6 | 5g | $33 | 2026-04-30 | Buy |
| TCI Chemical | A1437 | 2-Chloro-4-methylaniline >98.0%(GC)(T) | 615-65-6 | 25g | $129 | 2026-04-30 | Buy |
| Usbiological | 416798 | 2-Chloro-4-methylaniline | 615-65-6 | 1g | $319 | 2026-06-03 | Buy |
| Usbiological | 416798 | 2-Chloro-4-methylaniline | 615-65-6 | 5g | $403 | 2026-06-03 | Buy |
2-Chloro-4-methylaniline Chemical Properties,Uses,Production
Description
2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry. It is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.
Chemical Properties
clear yellow to pale brown liquid
Chemical Properties
The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
Uses
2-Chloro-4-methylaniline is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.
Uses
2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry.
Safety Profile
Poison by ingestion. A severe eye and skin irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx. See also other chloro toluidine entries.
Synthesis
The substrate 3-chloro-4-nitrotoluene was dissolved in MeOH (HPLC grade, 0.1 M). At room temperature in the presence of 0.5 mol% SiliaCat Hydrogenation was carried out in the presence of Pd0. The resulting mixture was degassed twice, replacing the vacuum with H2 each time. The reaction mixture was attached to a hydrogen balloon. The reaction mixture was stirred for 2 hours. The catalyst was recovered by filtration. Rinse with MeOH and dry under vacuum. The filtrate was concentrated by GC/MS analysis to give the product.
Potential Exposure
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.
Shipping
UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials
Incompatibilities
Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.
2-Chloro-4-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
View Lastest Price from 2-Chloro-4-methylaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 2-Chloro-4-methylaniline
615-65-6
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
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2025-05-23 | 2-Chloro-4-methylaniline
615-65-6
|
$45.00 | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd | |
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2022-02-22 | 2-Chloro-4-methylaniline
615-65-6
|
1KG | 99.2% | 100 tons | Honest Joy Holdings Limited
|
-

- 2-Chloro-4-methylaniline
615-65-6
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- 2-Chloro-4-methylaniline
615-65-6
- $45.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-

- 2-Chloro-4-methylaniline
615-65-6
- $0.00
- 99.2%
- Honest Joy Holdings Limited
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