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ChemicalBook >> CAS DataBase List >>2-Chloro-4-methylaniline

2-Chloro-4-methylaniline

CAS No.
615-65-6
Chemical Name:
2-Chloro-4-methylaniline
Synonyms
oro-4-methyL;2-Chlor-4-toluidin;2-chloro-p-toluidin;2-chlor-4-toluidine;2-CHLORO-4-TOLUIDINE;2-CHLORO-P-TOLUIDINE;2-Chloro-4-methylani;p-Toluidine, 2-chloro-;4-AMINO-3-CHLOROTOLUENE;3-CHLORO-4-AMINOTOLUENE
CBNumber:
CB4349929
Molecular Formula:
C7H8ClN
Molecular Weight:
141.6
MDL Number:
MFCD00007666
MOL File:
615-65-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:55:18
Product description Number Pack Size Price
2-Chloro-4-methylaniline 98% 125075 5g $45.4
2-Chloro-4-methylaniline >98.0%(GC)(T) A1437 5g $33
2-Chloro-4-methylaniline >98.0%(GC)(T) A1437 25g $129
2-Chloro-4-methylaniline 416798 1g $319
2-Chloro-4-methylaniline 416798 5g $403
More product size

2-Chloro-4-methylaniline Properties

Melting point 7 °C (lit.)
Boiling point 223-225 °C (lit.)
Density 1.151 g/mL at 25 °C (lit.)
refractive index n20/D 1.575(lit.)
Flash point 211 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility methanol: soluble
form Liquid
pka 3.09±0.10(Predicted)
color Clear yellow to pale brown
BRN 774514
Stability Acid Sensitive, Light Sensitive
InChI 1S/C7H8ClN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3
InChIKey XGYLSRFSXKAYCR-UHFFFAOYSA-N
SMILES Cc1ccc(N)c(Cl)c1
CAS DataBase Reference 615-65-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII K59ISJ2KO1
NIST Chemistry Reference Benzenamine, 2-chloro-4-methyl-(615-65-6)
EPA Substance Registry System Benzenamine, 2-chloro-4-methyl- (615-65-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS05,GHS06,GHS07,GHS08
Signal word  Danger
Hazard statements  H301+H311+H331-H319-H370-H372-H402-H302+H312+H332-H315-H318-H412-H302-H312-H331-H373
Precautionary statements  P304+P340-P501a-P260-P264-P270-P271-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P307+P311-P403+P233-P405-P501-P273-P280-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38-22-33
Safety Statements  36/37-37/39-26-45-36/37/39
RIDADR  UN 2239 6.1/PG III (CHLOROTOLUIDINES, SOLID)
RIDADR  UN 3429 6.1/PG III (CHLOROTOLUIDINES, LIQUID)
WGK Germany  3
RTECS  XU5110000
8-9-23
Hazard Note  Harmful
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29214200
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Dam. 1
Skin Irrit. 2
Hazardous Substances Data 615-65-6(Hazardous Substances Data)
NFPA 704
0
2 0

2-Chloro-4-methylaniline price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 125075 2-Chloro-4-methylaniline 98% 615-65-6 5g $45.4 2023-01-07 Buy
TCI Chemical A1437 2-Chloro-4-methylaniline >98.0%(GC)(T) 615-65-6 5g $33 2026-04-30 Buy
TCI Chemical A1437 2-Chloro-4-methylaniline >98.0%(GC)(T) 615-65-6 25g $129 2026-04-30 Buy
Usbiological 416798 2-Chloro-4-methylaniline 615-65-6 1g $319 2026-06-03 Buy
Usbiological 416798 2-Chloro-4-methylaniline 615-65-6 5g $403 2026-06-03 Buy
Product number Packaging Price Buy
125075 5g $45.4 Buy
A1437 5g $33 Buy
A1437 25g $129 Buy
416798 1g $319 Buy
416798 5g $403 Buy

2-Chloro-4-methylaniline Chemical Properties,Uses,Production

Description

2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry. It is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.

Chemical Properties

clear yellow to pale brown liquid

Chemical Properties

The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.

Uses

2-Chloro-4-methylaniline is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.

Uses

2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry.

Safety Profile

Poison by ingestion. A severe eye and skin irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx. See also other chloro toluidine entries.

Synthesis

The substrate 3-chloro-4-nitrotoluene was dissolved in MeOH (HPLC grade, 0.1 M). At room temperature in the presence of 0.5 mol% SiliaCat Hydrogenation was carried out in the presence of Pd0. The resulting mixture was degassed twice, replacing the vacuum with H2 each time. The reaction mixture was attached to a hydrogen balloon. The reaction mixture was stirred for 2 hours. The catalyst was recovered by filtration. Rinse with MeOH and dry under vacuum. The filtrate was concentrated by GC/MS analysis to give the product.

Potential Exposure

Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.

Shipping

UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials

Incompatibilities

Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.

2-Chloro-4-methylaniline Preparation Products And Raw materials

Global( 284)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7245 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Fluoropharm Co., Ltd.
+86-0571-85586753 +86-13336034509 sales@fluoropharm.com China 1445 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88298848 info@edengenechem.com China 2165 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5600 58

View Lastest Price from 2-Chloro-4-methylaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4-methylaniline pictures 2025-12-01 2-Chloro-4-methylaniline
615-65-6
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Chloro-4-methylaniline pictures 2025-05-23 2-Chloro-4-methylaniline
615-65-6
$45.00 1kg 99% 20 tons Hebei Zhuanglai Chemical Trading Co Ltd
2-Chloro-4-methylaniline pictures 2022-02-22 2-Chloro-4-methylaniline
615-65-6
1KG 99.2% 100 tons Honest Joy Holdings Limited
3-CHLORO-4-AMINOTOLUENE 4-AMINO-3-CHLOROTOLUENE 2-CHLORO-P-TOLUIDINE 2-CHLORO-4-METHYLANILINE 2-CHLORO-4-TOLUIDINE 1-AMINO-2-CHLORO-4-METHYLBENZENE 2-Chlor-4-toluidin 2-chlor-4-toluidin(czech) 2-Chloro-4-methylbenzamine 2-chloro-4-methyl-benzenamin 2-Chloro-4-Methyl-Benzenamine 2-chloro-p-toluidin 4-Methyl-2-chloroaniline p-Toluidine, 2-chloro- ORTHO CHLORO PARA TOLUIDINE 2-CHLORO-PARA-TOLUIDINE 2-chlor-4-toluidine 2-CHLORO-4-METHYLANILINE / 4-AMINO-3-CHLOROTOLUENE 2-Chloro-p-toluidine, 4-Amino-3-chlorotoluene 2-Chloro-4-methylaniline ,98% 2-Chloro-4-methylbenzen-1-amine 2-Chloro-4-methylani 4-Amino-3-chlorotoluene 2-Chloro-p-toluidine 2-Chloro-4-methylaniline 98% oro-4-methyL 2-Chloro-p-toluidineSolution,100mg/L,1ml 2-Chloro-4-methylaniline > 2-Chloro-p-toluidineSolution,100mg/L,5x1ml Benzenamine, 2-chloro-4-methyl- 2-Chloro-4-methylaniline ISO 9001:2015 REACH 2-Chloro-4-methylaniline, ≥ 98.0% Flufenamic Acid Impurity 25 2-chloro-4-methylbenzenemethylamine 615-65-6 615-65-9 ClC6H3CH3NH2 C7H8ClN Nitrogen Compounds Organic Building Blocks C7 Building Blocks Amines API Intermediate Anilines, Aromatic Amines and Nitro Compounds Intermediates of Dyes and Pigments
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