7-BENZYLOXY-4-CHLOROQUINOLINE
- CAS No.
- 178984-56-0
- Chemical Name:
- 7-BENZYLOXY-4-CHLOROQUINOLINE
- Synonyms
- 102579;4-chloro-7-(phenylMethoxy;4-chloro-7-benzoxyquinoline;4-chloro-7-phenoxy-quinoline;7-BENZYLOXY-4-CHLOROQUINOLINE;4-chloro-7-phenylmethoxyquinoline;Quinoline, 4-chloro-7-(phenylmethoxy)-;7-BENZYLOXY-4-CHLOROQUINOLINE ISO 9001：2015 REACH
- CBNumber:
- CB4420424
- Molecular Formula:
- C16H12ClNO
- Molecular Weight:
- 269.73
- MDL Number:
- MFCD06659039
- MOL File:
- 178984-56-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 7-(Benzyloxy)-4-chloroquinoline | 072748 | 250.00mg | $231 |
| 7-(Benzyloxy)-4-chloroquinoline | 072748 | 1.00g | $500 |
| 7-(Benzyloxy)-4-chloroquinoline | 072748 | 5.00g | $1428 |
| 7-(Benzyloxy)-4-chloroquinoline 97% | AA0026L7 | 1g | $33 |
| 7-(Benzyloxy)-4-chloroquinoline 97% | AA0026L7 | 5g | $116 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
7-BENZYLOXY-4-CHLOROQUINOLINE price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 072748 | 7-(Benzyloxy)-4-chloroquinoline | 178984-56-0 | 250.00mg | $231 | 2026-05-18 | Buy |
| Matrix Scientific | 072748 | 7-(Benzyloxy)-4-chloroquinoline | 178984-56-0 | 1.00g | $500 | 2026-05-18 | Buy |
| Matrix Scientific | 072748 | 7-(Benzyloxy)-4-chloroquinoline | 178984-56-0 | 5.00g | $1428 | 2026-05-18 | Buy |
| aablocks | AA0026L7 | 7-(Benzyloxy)-4-chloroquinoline 97% | 178984-56-0 | 1g | $33 | 2026-05-28 | Buy |
| aablocks | AA0026L7 | 7-(Benzyloxy)-4-chloroquinoline 97% | 178984-56-0 | 5g | $116 | 2026-05-28 | Buy |
7-BENZYLOXY-4-CHLOROQUINOLINE Chemical Properties,Uses,Production
Synthesis
749922-34-7
178984-56-0
Step 3) Synthesis of 7-(benzyloxy)-4-chloroquinoline: 7-(benzyloxy)quinolin-4-ol (72 g, 287 mmol) was suspended in toluene (134 mL), and phosphorus trichloride (44 g, 287 mmol, source: Tianjin FuChen Chem. Co. Ltd.) was added. The suspension was heated to 120 °C and maintained for 1 hour. After completion of the reaction, the mixture was cooled to 70 °C and diluted with EtOAc (600 mL). The resulting mixture was stirred in an ice bath for 30 min and cooled to 15 °C. Subsequently, the mixture was neutralized with 3M NaOH aqueous solution to pH 7~8, keeping the solution temperature below 20°C during the process. The aqueous layer was separated and the organic layer was extracted with EtOAc. The combined organic layers were washed with brine (200 mL), dried over anhydrous Na2SO4, and concentrated in vacuum to give 7-benzyloxy-4-chloroquinoline as a light yellow solid (70.8 g, 91.6% yield). Mass spectrum (ESI, positive ion mode) m/z: 270.1 [M + 1]; 1H NMR (400 MHz, DMSO-d6) δ: 5.31 (s, 2H), 7.35 (t, 1H), 7.42 (t, J = 7.2Hz, 2H), 7.47 (dd, J = 2.8Hz, J = 9.2Hz, 1H), 7.52 (d, J = 7.6 Hz, 2H), 7.13 (t, J = 4.8 Hz, 2H), 8.11 (d, J = 9.6 Hz, 1H), 8.75 (d, J = 4.8 Hz, 1H).
References
[1] Patent: US2012/219522, 2012, A1. Location in patent: Page/Page column 20
7-BENZYLOXY-4-CHLOROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| Jiangsu Qingquan Chemical Co., Ltd. | +86-571-86589381,86589382,86589383 | sales1@qqpharm.com | CHINA | 154 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28509 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 7-BENZYLOXY-4-CHLOROQUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-07-06 | 7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
|
$6.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 7-BENZYLOXY-4-CHLOROQUINOLINE
178984-56-0
- $6.00
- 99%
- Career Henan Chemical Co
