2-(2-Methoxyethoxy)acetic acid
- CAS No.
- 16024-56-9
- Chemical Name:
- 2-(2-Methoxyethoxy)acetic acid
- Synonyms
- DOHA;TIMTEC-BB SBB008497;2-(2-Methoxyoxyacid;3,6-DIOXAHEPTANOIC ACID;2-(2-Methoxyethoxy)Acetic;(2-Methoxyethoxy)essigsure;(2-methoxyethoxy)acetic acid;2-(2-METHOXYETHOXY)ACETIC ACID;o-(2-methoxyethyl)glycolic acid;2-(2-methoxyethoxy)ethanoic acid
- CBNumber:
- CB4434197
- Molecular Formula:
- C5H10O4
- Molecular Weight:
- 134.13
- MDL Number:
- MFCD00044097
- MOL File:
- 16024-56-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(2-Methoxyethoxy)acetic acid technical grade | 407011 | 250ml | $380 |
| 2-(2-Methoxyethoxy)acetic acid technical grade | 407011 | 1l | $933 |
| 2-(2-Methoxyethoxy)acetic Acid (90%) | TRC-M262785-25G | 25g | $246 |
| 2-(2-Methoxyethoxy)acetic Acid (90%) | TRC-M262785-10G | 10g | $153 |
| 2-(2-Methoxyethoxy)acetic Acid | 159148 | 10g | $403 |
| More product size | |||
| Boiling point | 245-250 °C (lit.) |
|---|---|
| Density | 1.18 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Chloroform, DMSO, Methanol |
| form | Oil |
| pka | 3.40±0.10(Predicted) |
| color | Clear Colourless |
| Water Solubility | Fully miscible in water. |
| BRN | 1753567 |
| InChI | 1S/C5H10O4/c1-8-2-3-9-4-5(6)7/h2-4H2,1H3,(H,6,7) |
| InChIKey | CLLLODNOQBVIMS-UHFFFAOYSA-N |
| SMILES | COCCOCC(O)=O |
| CAS DataBase Reference | 16024-56-9(CAS DataBase Reference) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 |
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 1 |
| HazardClass | 8 |
| PackingGroup | II |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Skin Corr. 1B |
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
2-(2-Methoxyethoxy)acetic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 407011 | 2-(2-Methoxyethoxy)acetic acid technical grade | 16024-56-9 | 250ml | $380 | 2026-04-30 | Buy |
| Sigma-Aldrich | 407011 | 2-(2-Methoxyethoxy)acetic acid technical grade | 16024-56-9 | 1l | $933 | 2023-06-20 | Buy |
| TRC | TRC-M262785-25G | 2-(2-Methoxyethoxy)acetic Acid (90%) | 16024-56-9 | 25g | $246 | 2026-06-03 | Buy |
| TRC | TRC-M262785-10G | 2-(2-Methoxyethoxy)acetic Acid (90%) | 16024-56-9 | 10g | $153 | 2026-06-03 | Buy |
| Usbiological | 159148 | 2-(2-Methoxyethoxy)acetic Acid | 16024-56-9 | 10g | $403 | 2026-06-03 | Buy |
2-(2-Methoxyethoxy)acetic acid Chemical Properties,Uses,Production
Chemical Properties
Colorless to pale yellow liquid
Uses
2-(2-Methoxyethoxy)acetic Acid is a urinary metabolite of Diglyme (D446300) that is a reproductive toxin. 2-(2-Methoxyethoxy)acetic Acid can be used as a biomarker of exposure for jet fuel JP-8 workers.
Synthesis
109-86-4
5292-43-3
16024-56-9
General procedure for the synthesis of methoxyethoxyacetic acid from 2-methoxyethanol and tert-butyl bromoacetate: 2-methoxyethanol (10 g, 131.4 mmol) and potassium tert-butoxide (17.67 g, 157.68 mmol) were dissolved in 100 mL of tetrahydrofuran (THF). The reaction mixture was heated to 45 °C, maintained for 1 h and then cooled to room temperature. To the above mixture was added tert-butyl bromoacetate (25.63 g, 131.41 mmol) and the reaction was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was concentrated and the residue was dissolved in water. The pH of the aqueous phase was adjusted to 12-12.5 with 1 M sodium hydroxide aqueous solution and stirring was continued for 12-14 hours at room temperature. Subsequently, the pH of the aqueous phase was adjusted with 10% aqueous phosphoric acid solution to 2. The product was extracted with dichloromethane (DCM). The DCM was removed by rotary evaporator to give 2-(2-methoxyethoxy)acetic acid as an oil (4.1 g, 23% yield).
References
[1] Patent: WO2015/79459, 2015, A1. Location in patent: Paragraph 00261
2-(2-Methoxyethoxy)acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Xiamen Shindano Biotechnology Co.,ltd | 0592-6266840 15750707980 | sales@chemsdano.com | China | 291 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD. | +86-0532-8699-9256 +8615254267723 | kaley@cnfdevelop.com | China | 1410 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9545 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 2-(2-Methoxyethoxy)acetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-17 | 2-(2-Methoxyethoxy)acetic acid
16024-56-9
|
100G | 90%min | 30KG/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2020-01-13 | 2-(2-Methoxyethoxy)acetic acid
16024-56-9
|
$6.68 | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 2-(2-Methoxyethoxy)acetic acid
16024-56-9
- $0.00
- 90%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-(2-Methoxyethoxy)acetic acid
16024-56-9
- $6.68
- 97%-99%
- Career Henan Chemical Co
