D-Glucono-1,5-lactone
- CAS No.
- 90-80-2
- Chemical Name:
- D-Glucono-1,5-lactone
- Synonyms
- GLUCONOLACTONE;GLUCONO-DELTA-LACTONE;GDL;D-GLUCONO-1,5-LACTONE;(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-one;DELTA-GLUCONOLACTONE;Glucosactone;Glucono-δ-Lactone;Glucono;Glucolactone
- CBNumber:
- CB4494337
- Molecular Formula:
- C6H10O6
- Molecular Weight:
- 178.14
- MDL Number:
- MFCD00006647
- MOL File:
- 90-80-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Gluconolactone certified reference material, pharmaceutical secondary standard | PHR3656 | 200MG | $172 |
| Gluconolactone meets USP testing specifications | G2164 | 1kg | $115 |
| D-(+)-Glucono-delta-lactone for synthesis | 8.43794 | 100g | $67.8 |
| Gluconolactone - CAS 90-80-2 - Calbiochem An oxidation product of glucose by glucose oxidase. | 347425 | 500g | $128 |
| Gluconolactone United States Pharmacopeia (USP) Reference Standard | 1294150 | 100mg | $525 |
| More product size | |||
| Melting point | 160 °C (dec.)(lit.) |
|---|---|
| Boiling point | 230.35°C (rough estimate) |
| alpha | 65 º (c=1,H2O) |
| Density | 0.6 |
| bulk density | 750kg/m3 |
| refractive index | 63.5 ° (C=10, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 590g/l Hydrolysis |
| form | Crystalline Powder |
| pka | 12.06±0.60(Predicted) |
| color | White to off-white |
| PH | 3.6 (10g/l, H2O, 20℃) |
| Odor | wh. cryst. powd., pract. odorless |
| biological source | microbial |
| Water Solubility | 500 g/L (20 ºC) |
| Merck | 14,4457 |
| BRN | 83286 |
| Major Application | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING CHELATING |
| Cosmetic Ingredient Review (CIR) | D-(+)-Glucono-1,5-lactone (90-80-2) |
| InChI | 1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1 |
| InChIKey | PHOQVHQSTUBQQK-SQOUGZDYSA-N |
| SMILES | OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O |
| LogP | -2.38 |
| CAS DataBase Reference | 90-80-2(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | GLUCONO-DELTA LACTONE |
| FDA 21 CFR | 155.120; 184.1318 |
| EWG's Food Scores | 1 |
| FDA UNII | WQ29KQ9POT |
| NIST Chemistry Reference | D-Gluconic acid, «delta»-lactone(90-80-2) |
| EPA Substance Registry System | .delta.-Gluconolactone (90-80-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 21-36/38-46-62-63 | |||||||||
| Safety Statements | 24/25-53-36/37-26-25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LZ5184000 | |||||||||
| F | 21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29322090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 90-80-2(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
D-Glucono-1,5-lactone price More Price(77)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3656 | Gluconolactone certified reference material, pharmaceutical secondary standard | 90-80-2 | 200MG | $172 | 2026-04-30 | Buy |
| Sigma-Aldrich | G2164 | Gluconolactone meets USP testing specifications | 90-80-2 | 1kg | $115 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.43794 | D-(+)-Glucono-delta-lactone for synthesis | 90-80-2 | 100g | $67.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 347425 | Gluconolactone - CAS 90-80-2 - Calbiochem An oxidation product of glucose by glucose oxidase. | 90-80-2 | 500g | $128 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1294150 | Gluconolactone United States Pharmacopeia (USP) Reference Standard | 90-80-2 | 100mg | $525 | 2026-04-30 | Buy |
D-Glucono-1,5-lactone Chemical Properties,Uses,Production
Description
Delta-Gluconolactone (GDL) is a lactone of the D-gluconate. It is a natural constituent of many foods. It can be found in honey, fruit juices, wine and many-fermented products1-3. It is used as a food additive with the E number E575 used as a sequestrant, an acidifier (it lower the pH and also help preserve the food from deterioration by enzymes and organisms), or a curing, pickling, or leavening agent. GDL has been marketed for use in feta cheese. GDL is neutral, but hydrolyses in water to gluconic acid that is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It can be used as nutritional supplement in beverage such as in Instant Drinks, Syrups, RTD Tea and Coffee, Sports and Energy Drinks, Waters.
Description
Glucono delta-lactone (C6H10O6), molecular weight 178.14, is an inner ester of gluconic acid. Commonly named gluconolactone, other synonyms include D-gluconic acid delta-lactone, D-glucono- 1, 5-lactone, and D-delta-gluconolactone. Some of its earliest uses as a food ingredient were as a flavoring (e.g., sherbets) and to reduce fat absorption in doughnuts and cones. Glucono deltalactone tastes sweet initially and has a slightly acid-aftertaste.
Chemical Properties
Powder
Uses
Geogard(R)Ultra is a synergistic blend of gluconolactone and sodium benzoate. This blend provides broad spectrum protection against product spoilage in a variety of personal care formulations. Product Data Sheet
Uses
(GDL) An acidulant. It hydrolyzes to form gluconic acid in water solution and thereby creates the desired pH. The rate of acid formation is affected by temperature, concentration, and the pH of the solution. It has low acid release at room temperature and accelerated conversion into gluconic acid at high temperatures. It is readily soluble with a solubility of 59 g in 100 ml of water at 20°C. It functions as a leavening agent, acidulant, curing and pickling agent, and pH control agent. It is comparatively less tart/sour than other food acids. It is used in baked goods, fish products, desserts, and dressings.
Uses
gluconolactone is used in cosmetics for its anti-acne properties. It can also help improve skin hydration given its water-binding ability. In addition, formulators may select gluconolactone for its action as a product stabilizer (chelating agent). Some studies indicate potential free-radical scavenging capacities as well. These properties would make it particularly relevant for use in making anti-aging, moisturizing, and possibly sun care products.
Uses
a product of the oxidation of glucose by glucose oxidase
Uses
A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.
Uses
D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to achieve a curing, pickling or leavening effect.
Uses
Component of many cleaning cmpds because of the sequestering ability of the gluconate radical which remains active in alk solutions; in the dairy industry to prevent milkstone; in breweries to prevent beerstone; as latent acid catalyst for acid colloid resins, particularly in textile printing; as a coagulant for tofu.
Preparation
Glucono delta-lactone is prepared commercially by the oxidation of glucose with bromine water.
Definition
ChEBI: D-glucono-1,5-lactone is an aldono-1,5-lactone obtained from D-gluconic acid. It has a role as an animal metabolite and a mouse metabolite. It is a gluconolactone and an aldono-1,5-lactone. It is functionally related to a D-gluconic acid.
General Description
Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as aβ-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.
Safety Profile
Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
Crystallise Dglucono-lactone from ethylene glycol monomethyl ether and dry for 1hour at 110o. It can be freed from other sugars via a column of Celite and charcoal (750g of each, 90 x 7.5cm) which is washed with 0.01N formic acid until the pH of the wash is equal to that of the entering acid. The lactone is applied in H2O and eluted with 0.01N formic acid (7L), then eluted with 7.5% EtOH/0.01N formic acid (8L), then 15% EtOH/0.01N formic acid (8L) which removes pentose and isomaltose (the optical rotation of the eluates are used for sugar detection) and finally elution with aqueous formic acid provides glucolactone which is obtained by evaporating or freeze drying. Its solubility in H2O is 60% and 1% in EtOH. A solution in H2O is slightly acidic, and the lactone dissolves in an equivalent of aqueous NaOH to form sodium D-gluconate [527-07-1] M 218.1, m 2002 0 6o(dec), [ ] D 25 +12o (c 10, H2O), pK2 5 3.6. [cf p 553, Smith & Whelan Biochemical Preparations 10 127 1963, Beilstein 3 IV 1255.]
D-Glucono-1,5-lactone Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Pioneer Biotech Co., Ltd . | 029-84385017; +8613259417953 | sales@pioneerbiotech.com | China | 1287 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| Nexal Inc | info@nexalinc.com | Americas | 31 | 58 | |
| Lianyungang Kaiyu Environmental Tech Co., Ltd. | +86-0086-19851820538 +8619851820538 | carlos@khonorchem.com | China | 314 | 58 |
| Nantong Provichem Biotech Co., Ltd. | +8617505220108 | sales@provichem.cn | China | 96 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
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Related Qustion
Ask a questionView Lastest Price from D-Glucono-1,5-lactone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | D-(+)-Glucono-1,5-lactone
90-80-2
|
1KG | 98% | 5000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-24 | D-(+)-Glucono-1,5-lactone
90-80-2
|
1kg | 99% | 20t | Jinan Jianfeng Chemical Co., Ltd | ||
 |
2026-07-23 | delta-Gluconolactone
90-80-2
|
0.99 | RongNa Biotechnology Co.,Ltd |
-
- D-(+)-Glucono-1,5-lactone
90-80-2
- $0.00
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- D-(+)-Glucono-1,5-lactone
90-80-2
- 99%
- Jinan Jianfeng Chemical Co., Ltd
-
- delta-Gluconolactone
90-80-2
- 0.99
- RongNa Biotechnology Co.,Ltd
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