ChemicalBook >> CAS DataBase List >>Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
- CAS No.
- 3641-14-3
- Chemical Name:
- Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
- Synonyms
- ethyl 5-aMino-1H-1,2,4-triazole-3-carboxylate;Asciminib Impurity 21;5-AMINO-1H-1 2 4-TRIAZOLE-3-CARBOXYLIC;3-Amino-5-(methoxycarbonyl)-1,2,4-triazole;Methyl 5-aMino-1,2,4-triazole-3-carboxylate;Methyl 3-aMino-1,2,4-triazole-5-carboxylate;Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate;Methyl 5-aMino-2H-1,2,4-triazole-3-carboxylate;methyl 3-azanyl-1H-1,2,4-triazole-5-carboxylate;2,4-triazole-3-carboxylicacid,5-amino-1h-methylester
- CBNumber:
- CB4498603
- Molecular Formula:
- C4H6N4O2
- Molecular Weight:
- 142.12
- MDL Number:
- MFCD00297193
- MOL File:
- 3641-14-3.mol
- MSDS File:
- SDS
Last updated:2026-05-28 04:44:00
| Product description | Number | Pack Size | Price |
| 5-Amino-1H-[1,2,4]-triazole-3-carboxylic acid methyl ester 96% | 573787 | 1g | $63.1 |
| Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | AS33655 | 5g | $28 |
| Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | AS33655 | 25g | $63 |
| Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | AS33655 | 100g | $140 |
| Methyl-5-amino-1H-1,2,4-triazole-3-carboxylate 98%(HPLC) | V0790 | 1g | $16 |
| More product size | |||
| Melting point | 218-222 °C (lit.) |
|---|---|
| Boiling point | 379.0±25.0 °C(Predicted) |
| Density | 1.505±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 8.92±0.40(Predicted) |
| form | Crystalline Powder |
| color | White |
| InChI | InChI=1S/C4H6N4O2/c1-10-3(9)2-6-4(5)8-7-2/h1H3,(H3,5,6,7,8) |
| InChIKey | MGRNUMFYRVKLEO-UHFFFAOYSA-N |
| SMILES | N1C(N)=NC(C(OC)=O)=N1 |
| CAS DataBase Reference | 3641-14-3(CAS DataBase Reference) |
| FDA UNII | 33BDL3S99S |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Skin Sens. 1 |
Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 573787 | 5-Amino-1H-[1,2,4]-triazole-3-carboxylic acid methyl ester 96% | 3641-14-3 | 1g | $63.1 | 2026-04-30 | Buy |
| Activate Scientific | AS33655 | Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | 3641-14-3 | 5g | $28 | 2026-06-04 | Buy |
| Activate Scientific | AS33655 | Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | 3641-14-3 | 25g | $63 | 2026-06-04 | Buy |
| Activate Scientific | AS33655 | Methyl 5-amino-4H-[1,2,4]triazole-3-carboxylate 95% | 3641-14-3 | 100g | $140 | 2026-06-04 | Buy |
| AK Scientific | V0790 | Methyl-5-amino-1H-1,2,4-triazole-3-carboxylate 98%(HPLC) | 3641-14-3 | 1g | $16 | 2026-06-04 | Buy |
Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate Chemical Properties,Uses,Production
Synthesis
67-56-1
3641-13-2
3641-14-3
To a solution of 5-amino-1H-1,2,4-triazole-3-carboxylic acid (3.9 g, 30.45 mmol) in methanol (100 mL) was slowly added thionyl chloride (SOCl2, 12 g, 100.84 mmol). The reaction mixture was stirred at 70 °C for 48 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The residue was dissolved in water (100 mL) and the pH was adjusted with saturated sodium bicarbonate (NaHCO3) solution to 8. Subsequently, the aqueous phase was extracted with dichloromethane (3 x 50 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford methyl 5-amino-1H-1,2,4-triazole-3-carboxylate as a white solid (800 mg, 65% yield). The product was confirmed by LC/MS (ES, m/z): [M + H]+ 143.0. 1H NMR (300 MHz, DMSO-d6): δ 3.85 (s, 3H).
References
[1] Chemical and Pharmaceutical Bulletin, 2004, vol. 52, # 2, p. 192 - 198
[2] Russian Journal of Applied Chemistry, 2006, vol. 79, # 5, p. 783 - 786
[3] Patent: WO2014/66743, 2014, A1. Location in patent: Paragraph 0146
Synthesis of Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate from Methanol and 3-Amino-1,2,4-triazole-5-carboxylic acid
Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate Preparation Products And Raw materials
Global( 172)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3997 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9070 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-15 | Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
3641-14-3
|
$1.00 | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-07-13 | Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
3641-14-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
3641-14-3
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate
3641-14-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
3641-14-3(Methyl 5-amino-1H-1,2,4-triazole-3-carboxylate)Related Search:
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3641-14-3
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