4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
- CAS No.
- 109073-77-0
- Chemical Name:
- 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
- Synonyms
- 2,2'-Bi(pyridine-4-methanol);2,2'-Bipyridine-4,4'-dimethanol;2,2'-Bipyridine-4,4'-bismethanol;1,4,7,10,18-Pentaazacyclopentadecane;1,10-phenanthroline-8-carboxylicacid;2,2'-Bipyridine]-4,4'-diyldimethanol;[2,2'-Bipyridine]-4,4'-diyldiMethanol;4,4'is(hydroxymethyl)-2,2'-bipyridine;4,4'-Bis(hydroxymethyl)-2,2'-bipyridyl;4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
- CBNumber:
- CB4511508
- Molecular Formula:
- C12H12N2O2
- Molecular Weight:
- 216.24
- MDL Number:
- MFCD06202808
- MOL File:
- 109073-77-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine >95.0%(GC)(T) | B3511 | 1g | $185 |
| 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine >95.0%(GC)(T) | B3511 | 5g | $555 |
| 4,4'-Bis(hydroxymethyl)-2,2-bipyridine ≥95% | 261801 | 1g | $356 |
| 4,4'-Bis(hydroxymethyl)-2,2-bipyridine ≥95% | 261801 | 5g | $762 |
| 4,4'-Bis(hydroxymethyl)-2,2-bipyridine | FB10299 | 10g | $900 |
| More product size | |||
| Melting point | 170.6-171.4 °C |
|---|---|
| Boiling point | 450.4±40.0 °C(Predicted) |
| Density | 1.281±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 12.94±0.10(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C12H12N2O2/c15-7-9-1-3-13-11(5-9)12-6-10(8-16)2-4-14-12/h1-6,15-16H,7-8H2 |
| InChIKey | RRXGRDMHWYLJSY-UHFFFAOYSA-N |
| SMILES | C1(C2=NC=CC(CO)=C2)=NC=CC(CO)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Safety Statements | 24/25 |
| HS Code | 29333990 |
4,4'-Bis(hydroxymethyl)-2,2'-bipyridine price More Price(77)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3511 | 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine >95.0%(GC)(T) | 109073-77-0 | 1g | $185 | 2026-04-30 | Buy |
| TCI Chemical | B3511 | 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine >95.0%(GC)(T) | 109073-77-0 | 5g | $555 | 2026-04-30 | Buy |
| Usbiological | 261801 | 4,4'-Bis(hydroxymethyl)-2,2-bipyridine ≥95% | 109073-77-0 | 1g | $356 | 2026-06-03 | Buy |
| Usbiological | 261801 | 4,4'-Bis(hydroxymethyl)-2,2-bipyridine ≥95% | 109073-77-0 | 5g | $762 | 2026-06-03 | Buy |
| Biosynth | FB10299 | 4,4'-Bis(hydroxymethyl)-2,2-bipyridine | 109073-77-0 | 10g | $900 | 2026-06-04 | Buy |
4,4'-Bis(hydroxymethyl)-2,2'-bipyridine Chemical Properties,Uses,Production
Uses
4,4‘-Bis(hydroxymethyl)-2,2’-bipyridine is a replication inhibitor that has been used in the treatment of cancer. It has also been shown to be effective in the treatment of metabolic disorders and chronic bronchitis.
Synthesis
1762-42-1
109073-77-0
The general procedure for the synthesis of 2,2'-bipyridine-4,4'-dimethanol from diethyl [2,2'-bipyridine]-4,4'-dicarboxylate was as follows: sodium borohydride (1.87 g, 49 mmol) was added to diethyl [2,2'-bipyridine]-4,4'-dicarboxylate (567 mg) dissolved in anhydrous ethanol (34 mL) , 1.89 mmol) suspension. The reaction mixture was refluxed for 3 hours. After completion of the reaction, it was cooled to room temperature and saturated ammonium chloride solution (24 mL/g NH4Cl) was added to quench the excess sodium borohydride. Subsequently, ethanol was removed by evaporation under reduced pressure. The resulting solid was dissolved in a minimal amount of water using an ultrasonic bath. The aqueous phase was extracted with ethyl acetate (5 x 34 mL) and the organic phases were combined and dried over anhydrous sodium sulfate. Finally, the organic phase was concentrated under reduced pressure to give a white powdery product in 91% yield.
References
[1] Chemical Communications, 2009, # 48, p. 7545 - 7547
[2] Electrochimica Acta, 2016, vol. 207, p. 313 - 320
[3] Journal of Physical Chemistry B, 1999, vol. 103, # 38, p. 8067 - 8079
[4] Patent: CN105793241, 2016, A. Location in patent: Paragraph 0129; 0159
[5] Tetrahedron, 2014, vol. 70, # 36, p. 6271 - 6275
4,4'-Bis(hydroxymethyl)-2,2'-bipyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13523716970 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8741 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhengzhou Yuanli Biological Technology Co., Ltd | 0086-371-67897895 18903711767 | sales02@zzyuanli.cn | CHINA | 149 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd. | 0431-80514535 13634302652 | Extension@chemextension.com | CHINA | 967 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-05 | 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
|
$70.00-328.00 | 5g | 0.98 | 10kg | Shanghai UCHEM Inc. | |
 |
2025-11-18 | 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-09-25 | 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
|
$1.40-32.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd |
-
- 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
- $70.00-328.00
- 0.98
- Shanghai UCHEM Inc.
-
- 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine
109073-77-0
- $1.40-32.00
- 99%
- Henan Fengda Chemical Co., Ltd
109073-77-0(4,4'-Bis(hydroxymethyl)-2,2'-bipyridine)Related Search:
1of4
