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ChemicalBook >> CAS DataBase List >>1,2,3,4-TETRAHYDROQUINOLIN-6-OL

1,2,3,4-TETRAHYDROQUINOLIN-6-OL

CAS No.
3373-00-0
Chemical Name:
1,2,3,4-TETRAHYDROQUINOLIN-6-OL
Synonyms
1,2,3,4-Tetrahydro-6-quinolinol;4-TETRAHYDROQUINOLIN-6-OL;1,2,3,4-TETRAHYDROQUINOLIN-6-OL;1,2,3,4-Tetrahydroquinoline-6-ol;6-Quinolinol, 1,2,3,4-tetrahydro-;5-hydroxy-1,2,3,4-Tetrahydro-quinolin;6-hydroxy-1,2,3,4-Tetrahydro-quinolin;6-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE;1,2,3,4-tetrahydroquinolin-6-ol hydrochloride;1,2,3,4-TETRAHYDROQUINOLIN-6-OL ISO 9001:2015 REACH
CBNumber:
CB4756109
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD00800243
MOL File:
3373-00-0.mol
MSDS File:
SDS
Last updated:2026-05-28 02:16:50
Product description Number Pack Size Price
1,2,3,4-Tetrahydroquinolin-6-ol >97% OR912575 1g $21
1,2,3,4-Tetrahydroquinolin-6-ol >97% OR912575 5g $63
1,2,3,4-Tetrahydroquinolin-6-ol >97% OR912575 25g $311
1,2,3,4-Tetrahydroquinolin-6-ol >97% OR912575 100g $1237
1,2,3,4-Tetrahydroquinolin-6-ol >97% OR912575 1g $21
More product size

1,2,3,4-TETRAHYDROQUINOLIN-6-OL Properties

Melting point 160 °C
Boiling point 337.5±31.0 °C(Predicted)
Density 1.141±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Methanol
form Solid
pka 11.48±0.20(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933499090

1,2,3,4-TETRAHYDROQUINOLIN-6-OL price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR912575 1,2,3,4-Tetrahydroquinolin-6-ol >97% 3373-00-0 1g $21 2026-06-04 Buy
Apolloscientific OR912575 1,2,3,4-Tetrahydroquinolin-6-ol >97% 3373-00-0 5g $63 2026-06-04 Buy
Apolloscientific OR912575 1,2,3,4-Tetrahydroquinolin-6-ol >97% 3373-00-0 25g $311 2026-06-04 Buy
Apolloscientific OR912575 1,2,3,4-Tetrahydroquinolin-6-ol >97% 3373-00-0 100g $1237 2026-06-04 Buy
Apolloscientific OR912575 1,2,3,4-Tetrahydroquinolin-6-ol >97% 3373-00-0 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
OR912575 1g $21 Buy
OR912575 5g $63 Buy
OR912575 25g $311 Buy
OR912575 100g $1237 Buy
OR912575 1g $21 Buy

1,2,3,4-TETRAHYDROQUINOLIN-6-OL Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A potential amoebicide.

Synthesis

6-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE

120-15-0

1,2,3,4-TETRAHYDROQUINOLIN-6-OL

3373-00-0

General procedure for the synthesis of 6-hydroxy-1,2,3,4-tetrahydroquinoline from 6-methoxy-1,2,3,4-tetrahydroquinoline: 6-methoxy-1,2,3,4-tetrahydroquinoline (3.00 g, 18.38 mmol) was dissolved in 50 mL of dichloromethane, and boron tribromide (13.81 g, 55.14 mmol) was slowly added at 0 °C. The reaction system was then warmed up to 15 °C with continuous stirring for 2 hours. After completion of the reaction, the reaction solution was concentrated and the reaction was quenched with 5 mL of methanol. To the reaction mixture, 20 mL of saturated sodium bicarbonate solution was added and stirred for 30 minutes. The reaction was extracted three times with 20 mL of ethyl acetate, the organic phases were combined and dried with anhydrous sodium sulfate. The organic phase was concentrated to give the crude product. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether/ethyl acetate from 3:1 to 1:1 gradient elution) to finally obtain 6-hydroxy-1,2,3,4-tetrahydroquinoline (1.95 g, yield 71.11%). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.24 (s, 1H), 6.22-6.35 (m, 3H), 4.93 (br.s, 1H), 3.02-3.10 (m, 2H), 2.57 (t, J = 6.4 Hz, 2H), 1.67-1.80 (m, 2H).

References

[1] Patent: EP3293177, 2018, A1. Location in patent: Paragraph 0222; 0224
[2] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 13, p. 3415 - 3418

1,2,3,4-TETRAHYDROQUINOLIN-6-OL Preparation Products And Raw materials

Global( 124)Suppliers
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Henan Fengda Chemical Co., Ltd
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Capot Chemical Co.,Ltd.
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View Lastest Price from 1,2,3,4-TETRAHYDROQUINOLIN-6-OL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2,3,4-TETRAHYDROQUINOLIN-6-OL pictures 2025-09-25 1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
$1.00-50.00 1KG 99% Henan Fengda Chemical Co., Ltd
1,2,3,4-TETRAHYDROQUINOLIN-6-OL pictures 2025-04-04 1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
1,2,3,4-TETRAHYDROQUINOLIN-6-OL pictures 2020-03-06 1,2,3,4-TETRAHYDROQUINOLIN-6-OL
3373-00-0
$1.00 1KG 99% 200kgs Career Henan Chemical Co

1,2,3,4-TETRAHYDROQUINOLIN-6-OL Spectrum

1,2,3,4-TETRAHYDROQUINOLIN-6-OL 6-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE 1,2,3,4-Tetrahydroquinoline-6-ol 6-hydroxy-1,2,3,4-Tetrahydro-quinolin 5-hydroxy-1,2,3,4-Tetrahydro-quinolin 1,2,3,4-tetrahydroquinolin-6-ol hydrochloride 6-Quinolinol, 1,2,3,4-tetrahydro- 1,2,3,4-TETRAHYDROQUINOLIN-6-OL ISO 9001:2015 REACH 4-TETRAHYDROQUINOLIN-6-OL 1,2,3,4-Tetrahydro-6-quinolinol 3373-00-0 Aromatics Heterocycles Quinolines, Quinazolines and derivatives pharmacetical
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