ChemicalBook >> CAS DataBase List >>Ethyl N-Boc-piperidine-4-carboxylate

Ethyl N-Boc-piperidine-4-carboxylate

Ethyl N-Boc-piperidine-4-carboxylate structure

CAS No.: 142851-03-4

Chemical Name:: Ethyl N-Boc-piperidine-4-carboxylate

Synonyms: 1-TERT-BUTYL 4-ETHYL PIPERIDINE-1,4-DICARBOXYLATE;N-BOC-4-CARBETHOXY PIPERIDINE;1-Boc-isonipecotic acid ethyl ester;Ethyl N-Boc-4-piperidinecarboxylate;Ethyl-N-BOC-4-Piperidine-4-Carboxylate;PIPERIDINE-1,4-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-ETHYL ESTER;calboxylate;BUTTPARK 153\33-50;ETHYL N-BOC-ISONIPECOTATE;1-Boc-piperidine-4-carboxyL

CBNumber:: CB4781820

Molecular Formula:: C13H23NO4

Molecular Weight:: 257.33

MDL Number:: MFCD01763998

MOL File:: 142851-03-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:31:04

Product description	Number	Pack Size	Price
Ethyl N-Boc-piperidine-4-carboxylate 97%	665150	5g	$46.3
Ethyl N-Boc-piperidine-4-carboxylate 97%	665150	25g	$176
Ethyl 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylate >97.0%(GC)	B2740	5g	$22
Ethyl 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylate >97.0%(GC)	B2740	25g	$86
Ethyl N-Boc-piperidine-4-carboxylate	TRC-E925260-5G	5g	$59
More product size

Request For Quotation

Ethyl N-Boc-piperidine-4-carboxylate Properties

Boiling point	120-135 °C/0.5 mmHg
Density	1.046 g/mL at 25 °C
refractive index	n20/D 1.458
Flash point	>230 °F
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform, Ethyl Acetate
pka	-2.23±0.40(Predicted)
form	Liquid
color	Clear colorless to pale yellow
InChI	InChI=1S/C13H23NO4/c1-5-17-11(15)10-6-8-14(9-7-10)12(16)18-13(2,3)4/h10H,5-9H2,1-4H3
InChIKey	MYHJCTUTPIKNAT-UHFFFAOYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCC(C(OCC)=O)CC1
CAS DataBase Reference	142851-03-4(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

target organs

Respiratory system

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

22-37/38-41

Safety Statements

26-39

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

Ethyl N-Boc-piperidine-4-carboxylate price More Price(76)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	665150	Ethyl N-Boc-piperidine-4-carboxylate 97%	142851-03-4	5g	$46.3	2026-04-30	Buy
Sigma-Aldrich	665150	Ethyl N-Boc-piperidine-4-carboxylate 97%	142851-03-4	25g	$176	2026-04-30	Buy
TCI Chemical	B2740	Ethyl 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylate >97.0%(GC)	142851-03-4	5g	$22	2026-04-30	Buy
TCI Chemical	B2740	Ethyl 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylate >97.0%(GC)	142851-03-4	25g	$86	2026-04-30	Buy
TRC	TRC-E925260-5G	Ethyl N-Boc-piperidine-4-carboxylate	142851-03-4	5g	$59	2026-06-03	Buy

Product number	Packaging	Price	Buy
665150	5g	$46.3	Buy
665150	25g	$176	Buy
B2740	5g	$22	Buy
B2740	25g	$86	Buy
TRC-E925260-5G	5g	$59	Buy

Ethyl N-Boc-piperidine-4-carboxylate Chemical Properties,Uses,Production

Chemical Properties

Liquid

Uses

Substrate used in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides leading to, for example, 4-pyridylpiperidinyl esters.

Uses

Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent to synthesize 3-amino-1-(5-indanyloxy)-2-propanol derivatives as sodium channel blockers to treat stroke patients. Ethyl N-Boc-piperidine-4-carboxylate is also used as a reagent to prepare inhibitors of tumour necrosis factor alpha-converting enzyme.

Synthesis

24424-99-5

142851-03-4

The general procedure for the synthesis of ethyl N-Boc-4-piperidinecarboxylate from di-tert-butyl dicarbonate was as follows: ethyl isopiperidinate (5.00 g, 0.032 mol) and triethylamine (4.9 mL, 0.035 mol) were dissolved in dichloromethane (25 mL) at 0 °C, and the dichloromethane of di-tert-butyl dicarbonate (7.2 g, 0.033 mol) was slowly added ( 25mL) solution. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, it was washed three times with potassium bisulfate solution and then once with brine. The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated in vacuum to afford the target product ethyl N-Boc-4-piperidinecarboxylate (8.23 g, 100% yield) as a colorless oil. The structure of the product was confirmed by 1H NMR (C6D6,500MHz) δ 3.88 (q, J=7.5Hz, 2H), 2.52 (m, 1H), 1.60-1.48 (m, 8H), 1.42 (s, 9H), 0.92 (t, 3H) and mass spectra (280.44 (M+Na)+).

References

[1] Patent: US2004/204397, 2004, A1
[2] Patent: US2003/144302, 2003, A1
[3] Patent: US2002/55631, 2002, A1
[4] Patent: US2002/86887, 2002, A1
[5] Patent: US5716965, 1998, A

Ethyl N-Boc-piperidine-4-carboxylate Preparation Products And Raw materials

Raw materials

Ethyl 4-piperidinecarboxylate Di-tert-butyl dicarbonate Dichloromethane Triethylamine

Preparation Products

2-Oxa-8-azaspiro[4.5]decane 1-Boc-4-[methoxy(methyl)carbamoyl]piperidine 1,4-Piperidinedicarboxylic acid, 4-(cyanomethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester Ethyl 4-Ethyl-4-piperidinecarboxylate Hydrochloride ETHYL N-BOC-4-(4-FLUOROBENZYL)PIPERIDINE-4-CARBOXYLATE

ethyl 4-methanesulfonylpiperidine-4-carboxylate hydrochloride tert-butyl 4-[3-(4-chlorophenyl)-1H-1,2,4-triazol-5-yl]piperidine-1-carboxylate 7-Boc-1-oxo-3-phenyl-2,7-diaza-spiro[3.5]nonane tert-butyl 2-benzyl-1-oxo-2,7-diazaspiro[3.5]nonane-7-carboxylate

1of2

Ethyl N-Boc-piperidine-4-carboxylate Suppliers

Global( 333)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Anhui Zhongda Biotechnology Co., Ltd	+8619956560829	justine@zhongda-biotech.com	China	286	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2165	58

Supplier	Advantage
Labnetwork lnc.	58
Anhui Zhongda Biotechnology Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58

View Lastest Price from Ethyl N-Boc-piperidine-4-carboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-11-03	Ethyl N-Boc-piperidine-4-carboxylate 142851-03-4	$10.00	1kg	99%	100tons	Anhui Zhongda Biotechnology Co., Ltd
2023-06-26	Ethyl N-Boc-piperidine-4-carboxylate 142851-03-4	$120.00	10g	99%	500kg/month	Hebei Mingeng Biotechnology Co., Ltd
2023-03-19	Ethyl N-Boc-piperidine-4-carboxylate 142851-03-4		1kg	98% Min	1000kg	LY Global chemicals co.,ltd .

Ethyl N-Boc-piperidine-4-carboxylate
142851-03-4
$10.00
99%
Anhui Zhongda Biotechnology Co., Ltd

Ethyl N-Boc-piperidine-4-carboxylate
142851-03-4
$120.00
99%
Hebei Mingeng Biotechnology Co., Ltd

Ethyl N-Boc-piperidine-4-carboxylate
142851-03-4
98% Min
LY Global chemicals co.,ltd .

Ethyl N-Boc-piperidine-4-carboxylate Spectrum

Ethyl N-Boc-piperidine-4-carboxylate(142851-03-4)¹HNMR Ethyl N-Boc-piperidine-4-carboxylate(142851-03-4)FT-IR

142851-03-4(Ethyl N-Boc-piperidine-4-carboxylate)Related Search:

Cyhalofop-butyl BUTYL OLEATE Ethyl propionate Ethylparaben Buprofezin

Cyclohexanecarboxylic acid ethyl ester OXALIC ACID Ethyl formate Trinexapac-ethyl ISOXADIFEN-ETHYL

Ethyl 4-piperidinecarboxylate Urethane Ethyl cyanoformate Ethyl nipecotate Ethyl acetate

2-Ethoxyethanol Isonipecotic acid Ethanol

1of4

1-BOC-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-TERT-BUTYL 4-ETHYL 1,4-PIPERIDINEDICARBOXYLATE 1-(TERT-BUTYL) 4-ETHYL TETRAHYDRO-1,4(2H)-PYRIDINEDICARBOXYLATE Ethyl N-Boc-piperidine-4-carboxylate N-BOC-4-piperidine forMic acid ethyl ester Ethyl 1-Boc-piperidine-4-carboxylate, 95+% N - bok - 4 - piperidine ethyl forMate Ethyl N-Boc-piperidine-4-calboxylate ETHYL N-BOC-ISONIPECOTATE ETHYL N-BOC-PIPERIDIN-4-YL CARBOXYLATE 1-Tert-butyl-4-ethyl 1,4-piperidie N-Boc-Piperidine-4-carboxylate or ethyl 1-Boc-piperidine-4-carboxylate 1-(tert-Butoxycarbonyl)-4-(ethoxycarbonyl)piperidine 1-tert-Butyl 4-ethyl piperidine-1,4-dicarboxylate 95+% Ethyl N-boc-piperidine-4-carboxylate Ethyl N-Boc-piperidine-4-carboxylate 97% ETHYL N-BOC-PIPERIDINE-4-CARBOXYLATE ETHYL 1-(TERT-BUTYLOXYCARBONYL)ISONIPECOTATE ETHYL 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINECARBOXYLATE ETHYL 1-TERT-BUTOXYCARBONYLPIPERIDINE-4-CARBOXYLATE DIMETHYLETHYL PIPERIDINEDICARBOXYLIC ACID ETHYL ESTER BUTTPARK 153\33-50 1-Boc-4-Carbethoxy Piperidine N-Butoxycarbonyl-4-carbethoxy piperidine Ethyl1-tert-buthoxycarbonylpyridine-4-carboxylate 1-(tert-butyl) 4-ethyl tetrahydro-1,4(2H)-pyridinedicarboxylate (en) Ethyl 1-(tert-butoxycarbonyl)-4-piperidinecarboxylate, Ethyl 1-(tert-Butyloxycarbonyl)isonipecotate, Piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester tert-butyl ethyl piperidine-1,4-dicarboxylate 1-Boc-isonipecotic acid ethyl ester, 97+% N-Boc-piperidine-4-carboxylic acid ethyl ester Ethyl piperidine-4-carboxylate, N-BOC protected 95+% 1-tert-butyl ester 4-ethyl ester 1-tert-Butyl 4-ethyl piperidine-1,4-dicarboxylate, 1-(tert-Butoxycarbonyl)-4-(ethoxycarbonyl)piperidine 1,4-Piperidinedicarboxylic acid, 1-(1,1-diMethylethyl) 4-ethyl ester N-Boc-piperidine-4-carboxylate, ethyl ester 1-Boc-4-piperidinecarboxylic Acid Ethyl Ester Piperidine-1,4-dicarboxylic Acid 1-tert-Butyl 4-Ethyl Ester Ethyl 1-Boc-4-piperidinecarboxylate Ethyl N-Boc-piperidine-4-carboxylate USP/EP/BP 1-O-tert-butyl 4-O-ethyl piperidine-1,4-dicarboxylate calboxylate N-BOC-4-Carbethoxy-4-Piperidone China manufacturing Ethyl N-Boc-piperidine-4-carboxylate 142851-03-4 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylic Acid Ethyl Ester China manufacturing Ethyl N-Boc-piperidine-4-carboxylate Ethyl 1-(tert-Butoxycarbonyl)-4-piperidinecarboxylate > 1-Boc-piperidine-4-carboxyL N-BOC isonipecotic acid ethyl ester N-BOC-4-CARBETHOXY PIPERIDINE PIPERIDINE-1,4-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-ETHYL ESTER Ethyl N-Boc-4-piperidinecarboxylate N-Boc-4-piperidinecarboxylic acid ethyl ester 1-Boc-isonipecotic acid ethyl ester 1-TERT-BUTYL 4-ETHYL PIPERIDINE-1,4-DICARBOXYLATE Ethyl-N-BOC-4-Piperidine-4-Carboxylate 142851-03-4 Esters Pyrans, Piperidines &Piperazines

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Ethyl N-Boc-piperidine-4-carboxylate

Ethyl N-Boc-piperidine-4-carboxylate Properties

SAFETY

Risk and Safety Statements

Ethyl N-Boc-piperidine-4-carboxylate price More Price(76)

Ethyl N-Boc-piperidine-4-carboxylate Chemical Properties,Uses,Production

Chemical Properties

Uses

Uses

Synthesis

References

Ethyl N-Boc-piperidine-4-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl N-Boc-piperidine-4-carboxylate Suppliers

View Lastest Price from Ethyl N-Boc-piperidine-4-carboxylate manufacturers

Ethyl N-Boc-piperidine-4-carboxylate Spectrum

142851-03-4(Ethyl N-Boc-piperidine-4-carboxylate)Related Search: