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ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE structure

CAS No.: 34127-22-5

Chemical Name:: ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE

Synonyms: ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE;3,6-Dichloro-5-ethylpyridazine-4-carbaldehyde;3,6-Dichloropyridazine-4-carboxylic acid ethyl ester;4-Pyridazinecarboxylic acid, 3,6-dichloro-, ethyl ester;ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE ISO 9001：2015 REACH

CBNumber:: CB4836667

Molecular Formula:: C7H6Cl2N2O2

Molecular Weight:: 221.04

MDL Number:: MFCD08704423

MOL File:: 34127-22-5.mol

MSDS File:: SDS

Last updated:2026-05-28 03:43:26

Product description	Number	Pack Size	Price
Ethyl 3,6-dichloropyridazine-4-carboxylate	JBA12722	10g	$472
Ethyl 3,6-dichloropyridazine-4-carboxylate	083513	1.00g	$874
Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	E38355	100mg	$79
Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	E38355	250mg	$93
Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	E38355	1g	$97

Request For Quotation

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Properties

Boiling point	364.2±37.0 °C(Predicted)
Density	1.433±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
pka	-3.52±0.10(Predicted)
Appearance	Light yellow to brown Solid-Liquid Mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H315-H319
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	JBA12722	Ethyl 3,6-dichloropyridazine-4-carboxylate	34127-22-5	10g	$472	2026-06-04	Buy
Matrix Scientific	083513	Ethyl 3,6-dichloropyridazine-4-carboxylate	34127-22-5	1.00g	$874	2026-05-18	Buy
Synthonix	E38355	Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	34127-22-5	100mg	$79	2026-05-06	Buy
Synthonix	E38355	Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	34127-22-5	250mg	$93	2026-05-06	Buy
Synthonix	E38355	Ethyl 3,6-dichloropyridazine-4-carboxylate 95+%	34127-22-5	1g	$97	2026-05-06	Buy

Product number	Packaging	Price	Buy
JBA12722	10g	$472	Buy
083513	1.00g	$874	Buy
E38355	100mg	$79	Buy
E38355	250mg	$93	Buy
E38355	1g	$97	Buy

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

64-17-5

3,6-Dichloropyridazine-4-carboxylic acid

51149-08-7

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE

34127-22-5

To a suspension of 3,6-dichloropyridazine-4-carboxylic acid (15.0 g, 78 mmol) in tetrahydrofuran (THF, 150 mL) was sequentially added ethanol (18.15 mL, 311 mmol) and 4-dimethylaminopyridine (DMAP, 0.950 g, 7.77 mmol). 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC, 16.39 g, 85 mmol) was added in batches over 1 min, and mild exothermic phenomena were observed during the reaction. The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was transferred to a dispensing funnel and neutralized by adding saturated aqueous sodium bicarbonate (NaHCO3) solution (150 mL). The aqueous phase was extracted with ether (3×250 mL), and the combined organic phases were washed with saturated saline (100 mL), dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: 20%→40% ethyl acetate/hexane solution; amount of silica gel: 300 g) to afford ethyl 3,6-dichloro-4-pyridazine-carboxylate (13.2 g, 59.7 mmol, 77% yield) as a colorless oil. The product was characterized as follows: 1H NMR (400 MHz, CDCl3) δ 7.88 (s, 1H), 4.50 (q, J = 7.0 Hz, 2H), 1.46 (t, J = 7.2 Hz, 3H); LCMS (ESI) m/e 221.1 [(M + H)+, theoretical value 221.0 (C7H7Cl2N2O2)].

References

[1] Patent: WO2018/98411, 2018, A1. Location in patent: Page/Page column 20; 21; 23; 24; 68; 69
[2] Patent: WO2008/130951, 2008, A1. Location in patent: Page/Page column 81
[3] Journal of Medicinal Chemistry, 1993, vol. 36, # 18, p. 2676 - 2688
[4] Patent: WO2008/130600, 2008, A2. Location in patent: Page/Page column 70
[5] Patent: WO2004/108707, 2004, A1. Location in patent: Page 53-54

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Ethanol 2-[2-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-6-methylpyran-4-ylidene]propanedinitrile 3,6-Dichloropyridazine-4-carboxylic acid 4-Dimethylaminopyridine n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride

Tetrahydrofuran

1of2

Preparation Products

ethyl 3-amino-6-chloropyridazine-4-carboxylate

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Suppliers

Global( 58)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	3997	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai Rlavie Technology Co ltd	+86-021-67759270 +8617717059219	sales@rlavie.com	China	1030	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5973	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	+86-0512-83500002 +8618662433356	3899766280@qq.com	China	26362	58
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd	+86-86-13383293380 +8613230482270	1919301810@qq.com	China	141	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai Rlavie Technology Co ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Labnetwork lnc.	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	58
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-08-07	Ethyl 3,6-dichloropyridazine-4-carboxylate 34127-22-5	$1.00	1Kg	98%	20T	Shaanxi Dideu Medichem Co. Ltd
2022-01-04	3,6-Dichloropyridazine-4-carboxylic acid ethyl ester 34127-22-5		1g	98%minHPLC	50kgs/month	Shanghai Rlavie Technology Co ltd
2020-01-10	ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE 34127-22-5	$1.00	1KG	98% HPLC	10 tons/month	Career Henan Chemical Co

Ethyl 3,6-dichloropyridazine-4-carboxylate
34127-22-5
$1.00
98%
Shaanxi Dideu Medichem Co. Ltd

3,6-Dichloropyridazine-4-carboxylic acid ethyl ester
34127-22-5
98%minHPLC
Shanghai Rlavie Technology Co ltd

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE
34127-22-5
$1.00
98% HPLC
Career Henan Chemical Co

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Spectrum

ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE(34127-22-5)¹HNMR

34127-22-5(ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE)Related Search:

3,6-Dichloropyridazine-4-carboxylic acid 3,6-Dichloropyridazine 3,6-dichloro-4-pyridazinecarboxaldehyde Methyl 3,6-dichloropyridazine-4-carboxylate SALOR-INT L349488-1EA

3,6-Dichloro-4-methylpyridazine ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE Pyridazine-4-carboxylic acid methyl ester 3-Chloro-5-methylpyridazine ETHYL 4-PYRIDAZINECARBOXYLATE