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ChemicalBook >> CAS DataBase List >>Tacalcitol

Tacalcitol

CAS No.
57333-96-7
Chemical Name:
Tacalcitol
Synonyms
trans-Calcitriol;TV 02;C12919;Bonalfa;PRI 2191;Tacalcital;Tacalcitol;Curatoderm;Tacalcitol RS;Tacalcitol (Standard)
CBNumber:
CB4875440
Molecular Formula:
C27H44O3
Molecular Weight:
416.64
MDL Number:
MOL File:
57333-96-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:29:24
Product description Number Pack Size Price
Tacalcitol ≥99% (HPLC) SMB00579 1MG $353
1,24-Dihydroxyvitamin D3 solution 50?μg/mL (Ethanol with 0.1%BHT (degassed)), certified reference material, ampule of 1?mL, Cerilliant? H-162 1ML $242
1,24-dihydroxy Vitamin D3 ≥98% 12079 500μg $89
1,24-dihydroxy Vitamin D3 ≥98% 12079 1mg $169
Tacalcitol Asreported 256796 1mg $516
More product size

Tacalcitol Properties

Boiling point 565.0±50.0 °C(Predicted)
Density 1.06
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility 20mg/mL in DMSO, 20mg/mL in DMF, 20mg/mL in Ethanol
pka 14.43±0.40(Predicted)
form Powder
color White to off-white
biological source synthetic (organic)
InChIKey BJYLYJCXYAMOFT-RSFVBTMBSA-N
SMILES [C@@H]1(O)C/C(=C/C=C2\CCC[C@@]3(C)[C@@]\2([H])CC[C@@H]3[C@H](C)CC[C@@H](O)C(C)C)/C(=C)[C@@H](O)C1
CAS DataBase Reference 57333-96-7(CAS DataBase Reference)
FDA UNII C2W72OJ5ZU
ATC code D05AX04
UNSPSC Code 12352205
NACRES NA.79

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
WGK Germany  WGK 3
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 1 Oral

Tacalcitol price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00579 Tacalcitol ≥99% (HPLC) 57333-96-7 1MG $353 2026-04-30 Buy
Sigma-Aldrich H-162 1,24-Dihydroxyvitamin D3 solution 50?μg/mL (Ethanol with 0.1%BHT (degassed)), certified reference material, ampule of 1?mL, Cerilliant? 57333-96-7 1ML $242 2026-04-30 Buy
Cayman Chemical 12079 1,24-dihydroxy Vitamin D3 ≥98% 57333-96-7 500μg $89 2021-12-16 Buy
Cayman Chemical 12079 1,24-dihydroxy Vitamin D3 ≥98% 57333-96-7 1mg $169 2021-12-16 Buy
Usbiological 256796 Tacalcitol Asreported 57333-96-7 1mg $516 2026-06-03 Buy
Product number Packaging Price Buy
SMB00579 1MG $353 Buy
H-162 1ML $242 Buy
12079 500μg $89 Buy
12079 1mg $169 Buy
256796 1mg $516 Buy

Tacalcitol Chemical Properties,Uses,Production

Description

Tacalcitol, the second vitamin D analog developed as a topical antipsoriatic, was introduced for keratosis, psoriasis, ichthyosis, pityriasis rubra pilaris and palmoplantar pustulosis and keratoderma. It shows improvement in appearance of skin lesions for psoriasis patients without significant side effects. In patients with psoriasis vulgaris, it effectively inhibits keratinocyte growth. Some in vitro studies have shown that tacalcitol inhibits interleukin-1-α-induced granulocyte macrophage colony-stimulating-factor mRNA expression of the human dermal microvascular endothelial cells, which may be involved in mediation of angioproliferation in skin inflammation.

Originator

Teijin (Japan)

Uses

Tacalcitol is a synthetic vitamin D3 analog.

Definition

ChEBI: Tacalcitol is a hydroxy seco-steroid that is calciol which carries hydroxy groups at positions 1S and 24R. It is a vitamin D3 analog which is used for the treatment of psoriasis vulgaris in adults, especially on the scalp. It has a role as an antipsoriatic, a vitamin D receptor agonist and an antineoplastic agent. It is a member of D3 vitamins, a hydroxy seco-steroid, a secondary alcohol and a seco-cholestane. It is functionally related to a calciol.

brand name

Bonalfa

Safety Profile

A poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors,

64190-52-9
57333-96-7
Synthesis of Tacalcitol from 1-(2-Hydroxy-1-methyl-ethyl)-7a-methyl-octahydro-inden-4-ol

Tacalcitol Preparation Products And Raw materials

Global( 153)Suppliers
Supplier Tel Email Country ProdList Advantage
HangZhou RunYan Pharma Technology Co.,LTD.
+8618882027439 sales2@runyanpharma.com China 302 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14015 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569266 +86-17392581500 1015@dideu.com China 3991 58
Nanjing Shizhou Biotechnology Co., Ltd 		+86-15850508050 sean.lv@synzest.com China 323 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Longyan Tianhua Biological Technology Co., Ltd 		0086 18039857276 18039857276 CHINA 2783 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Tacalcitol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tacalcitol pictures 2025-08-21 Tacalcitol
57333-96-7
 10g 99.0%min. HPLC 1000kg HangZhou RunYan Pharma Technology Co.,LTD.
Tacalcitol pictures 2021-07-13 Tacalcitol
57333-96-7
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Tacalcitol pictures 2021-07-09 Tacalcitol
57333-96-7
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
  • Tacalcitol pictures
  • Tacalcitol
    57333-96-7
  • 99.0%min. HPLC
  • HangZhou RunYan Pharma Technology Co.,LTD.
  • Tacalcitol pictures
  • Tacalcitol
    57333-96-7
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Tacalcitol pictures
  • Tacalcitol
    57333-96-7
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
(1α，3β-5Z，7E，24R)-9，10-Secoholesta-5，7，10(19)-triene-1，3，24-triol lα，24-Dihydroxycholecalciferol lα，24R-Dihy-droxyvitamin D3 [5Z,7E,24R,(+)]-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,24-triol 1α,24(R)-Dihydroxyvitamin D3 1α,24R-Dihydroxyvitamin D3 (1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol C12919 (1α,3β,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol Tacalcital 1α,24(R)-Dihydroxycholecalciferol 4-methylene-5Z-[2E-[(3aS)-octahydro-1R-[4R-hydroxy-1R,5-dimethylhexyl]-7aR-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol Tacalcitol 1-alpha-3-beta-5E,7E,24R)-9,10-Secocholesta-5,7,10,19-triene-1,3,24-triol 1a,24(R)-Dihydroxycholecalciferol 1a,24(R)-Dihydroxyvitamin D3 1a,24R-Dihydroxyvitamin D3 9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol, (1a,3b,5Z,7E,24R)- (9CI) Bonalfa Curatoderm PRI 2191 TV 02 1ALPHA,24(R)-DIHYDROXYVITAMIND3 TacalcitolQ: What is Tacalcitol Q: What is the CAS Number of Tacalcitol Q: What is the storage condition of Tacalcitol Q: What are the applications of Tacalcitol (1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R)-5-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)- Tacalcitol RS Tacalcitol (1,24(R)-Dihydroxyvitamin D3 (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol Tacalcitol(1,24-dihydroxy Vitamin D3) Tacalcitol in Methanol 1,24-Dihydroxyvitamin D3 solution Tacalcitol (Standard) trans-Calcitriol 57333-96-7 Vitamin D3 analogs
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