Methyl 3-bromo-5-nitrobenzoate
- CAS No.
- 6307-87-5
- Chemical Name:
- Methyl 3-bromo-5-nitrobenzoate
- Synonyms
- DK89898D;Methyl 3-bromo-5-nitrobenzoate;3-Bromo-5-nitro-benzoic acid met;Methyl3-bromo-5-nitrobenzoate98%;Methyl 3-bromo-5-nitrobenzoate 98%;3-Bromo-5-nitro-benzoic acid methyl ester;Benzoic acid, 3-bromo-5-nitro-, methyl ester
- CBNumber:
- CB4957694
- Molecular Formula:
- C8H6BrNO4
- Molecular Weight:
- 260.04
- MDL Number:
- MFCD09258759
- MOL File:
- 6307-87-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl 3-bromo-5-nitrobenzoate 98% | OR5288 | 1g | $21 |
| Methyl 3-bromo-5-nitrobenzoate 98% | OR5288 | 5g | $26 |
| Methyl 3-bromo-5-nitrobenzoate | 144413 | 5.00g | $88 |
| Methyl 3-bromo-5-nitrobenzoate | 144413 | 25.00g | $264 |
| Methyl 3-bromo-5-nitrobenzoate | 144413 | 100.00g | $628 |
| More product size | |||
| Melting point | 70 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 326.0±22.0 °C(Predicted) |
| Density | 1.673±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| color | Off-white to light brown |
| InChI | InChI=1S/C8H6BrNO4/c1-14-8(11)5-2-6(9)4-7(3-5)10(12)13/h2-4H,1H3 |
| InChIKey | DDJCZBFPZLYREP-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC([N+]([O-])=O)=CC(Br)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2916399090 |
Methyl 3-bromo-5-nitrobenzoate price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR5288 | Methyl 3-bromo-5-nitrobenzoate 98% | 6307-87-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR5288 | Methyl 3-bromo-5-nitrobenzoate 98% | 6307-87-5 | 5g | $26 | 2026-06-04 | Buy |
| Matrix Scientific | 144413 | Methyl 3-bromo-5-nitrobenzoate | 6307-87-5 | 5.00g | $88 | 2026-05-18 | Buy |
| Matrix Scientific | 144413 | Methyl 3-bromo-5-nitrobenzoate | 6307-87-5 | 25.00g | $264 | 2026-05-18 | Buy |
| Matrix Scientific | 144413 | Methyl 3-bromo-5-nitrobenzoate | 6307-87-5 | 100.00g | $628 | 2026-05-18 | Buy |
Methyl 3-bromo-5-nitrobenzoate Chemical Properties,Uses,Production
Uses
Methyl 3-bromo-5-nitrobenzoate is a pharmaceutical intermediate. Methyl 3-bromo-5-nitrobenzoate can be used to prepare 3-amidobenzoic acid derivatives such as 3-(4-trifluoromethylbenzoyl)amino-5-(2',6'-(2H)piperidinylphenyl)benzoic acid, which have P2Y receptor antagonist effects.
Synthesis
The preparation method is achieved through a two-step reaction: first, at 0°C, 3-nitrobenzoic acid is dissolved in concentrated sulfuric acid, N-bromosuccinimide is added, the reaction is carried out at 65°C for 2 hours, and 3-nitro-5-bromobenzoic acid is obtained after stirring with ice water, suction filtration, and drying, with a yield of 95%. Next, the product is dissolved in methanol, SOCl? is added dropwise at 0°C, the reaction is carried out at room temperature for 2 hours, and Methyl 3-bromo-5-nitrobenzoate is finally obtained after treatment with a sodium bicarbonate solution, extraction with ethyl acetate, drying, and column chromatography purification, with a yield of 86.46%.
References
[1] Chemistry - A European Journal, 2006, vol. 12, # 18, p. 4764 - 4774
[2] Journal of the American Chemical Society, 2013, vol. 135, # 46, p. 17408 - 17416
[3] Patent: WO2014/19685, 2014, A1. Location in patent: Page/Page column 13; 39
[4] Journal of Molecular Structure, 2013, vol. 1036, p. 505 - 509
[5] Collection of Czechoslovak Chemical Communications, 1973, vol. 38, p. 3496 - 3505
Methyl 3-bromo-5-nitrobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14015 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
View Lastest Price from Methyl 3-bromo-5-nitrobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | Methyl 3-bromo-5-nitrobenzoate
6307-87-5
|
$3.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2019-07-06 | Methyl 3-bromo-5-nitrobenzoate
6307-87-5
|
$200.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- Methyl 3-bromo-5-nitrobenzoate
6307-87-5
- $3.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- Methyl 3-bromo-5-nitrobenzoate
6307-87-5
- $200.00
- 98%
- Career Henan Chemical Co
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