2,6-Difluoro-4-nitrophenol
- CAS No.
- 658-07-1
- Chemical Name:
- 2,6-Difluoro-4-nitrophenol
- Synonyms
- 4-nitro-2,6-Difluorophenol;2,6-Difluoro-4-nitrophenol;Phenol, 2,6-difluoro-4-nitro-;2,6-Difluoro-4-nitrophenol 98%;2,6-Difluoro-4-nitrophenol，GC，97%;3,5-Difluoro-4-hydroxynitrobenzene
- CBNumber:
- CB4969909
- Molecular Formula:
- C6H3F2NO3
- Molecular Weight:
- 175.09
- MDL Number:
- MFCD07366521
- MOL File:
- 658-07-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,6-Difluoro-4-nitrophenol 98% | PC9845 | 1g | $30 |
| 2,6-Difluoro-4-nitrophenol 98% | PC9845 | 5g | $112 |
| 2,6-Difluoro-4-nitrophenol 98% | PC9845 | 25g | $516 |
| 2,6-Difluoro-4-nitrophenol 98% | PC9845 | 1g | $30 |
| 2,6-Difluoro-4-nitrophenol 98% | PC9845 | 5g | $112 |
| More product size | |||
| Melting point | 99.7-100.7°C |
|---|---|
| Boiling point | 254.5±40.0 °C(Predicted) |
| Density | 1.619±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | crystalline powder |
| pka | 4.28±0.44(Predicted) |
| color | Faint yellow |
| InChI | InChI=1S/C6H3F2NO3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H |
| InChIKey | KVVXRISUSPIMLJ-UHFFFAOYSA-N |
| SMILES | C1(O)=C(F)C=C([N+]([O-])=O)C=C1F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H335 |
| Precautionary statements | P261-P280-P312 |
| Hazard Codes | Xi |
| HS Code | 2908990000 |
2,6-Difluoro-4-nitrophenol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC9845 | 2,6-Difluoro-4-nitrophenol 98% | 658-07-1 | 1g | $30 | 2026-06-04 | Buy |
| Apolloscientific | PC9845 | 2,6-Difluoro-4-nitrophenol 98% | 658-07-1 | 5g | $112 | 2026-06-04 | Buy |
| Apolloscientific | PC9845 | 2,6-Difluoro-4-nitrophenol 98% | 658-07-1 | 25g | $516 | 2026-06-04 | Buy |
| Apolloscientific | PC9845 | 2,6-Difluoro-4-nitrophenol 98% | 658-07-1 | 1g | $30 | 2026-06-04 | Buy |
| Apolloscientific | PC9845 | 2,6-Difluoro-4-nitrophenol 98% | 658-07-1 | 5g | $112 | 2026-06-04 | Buy |
2,6-Difluoro-4-nitrophenol Chemical Properties,Uses,Production
Chemical Properties
Light yellow crystalline
Synthesis
28177-48-2
141-78-6
658-07-1
The general procedure for the synthesis of 2,6-difluoro-4-nitrophenol from 2,6-difluorophenol and ethyl acetate is as follows: with reference to Example 103, 2,6-difluorophenol (2.00 g) was dissolved in acetic acid (20 ml), and 60% nitric acid (1.20 ml) was slowly added dropwise under ice bath conditions. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the mixture was poured into ice water and extracted with ethyl acetate. The extract was washed with saturated saline and the organic layer was dried with anhydrous magnesium sulfate. The dried organic layer was filtered and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with the eluent being a mixed solvent with the volume ratio of hexane/ethyl acetate=3/1→2/1, resulting in the target compound 2,6-difluoro-4-nitrophenol (1.37 g, 51% yield) as a light yellow solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3), δppm: 7.95 (2H, m).
References
[1] Patent: US6555556, 2003, B1
2,6-Difluoro-4-nitrophenol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 2,6-Difluoro-4-nitrophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-02 | 2,6-Difluoro-4-nitrophenol
658-07-1
|
$22.00-88.00 | 1kg | 99% | 50kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2019-12-26 | 2,6-Difluoro-4-nitrophenol
658-07-1
|
$2.00 | 1KG | 98%MIN | Career Henan Chemical Co |
-
- 2,6-Difluoro-4-nitrophenol
658-07-1
- $22.00-88.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2,6-Difluoro-4-nitrophenol
658-07-1
- $2.00
- 98%MIN
- Career Henan Chemical Co
