5-Amino-o-cresol
- CAS No.
- 2835-95-2
- Chemical Name:
- 5-Amino-o-cresol
- Synonyms
- 4-AMINO-2-HYDROXYTOLUENE;5-AMINO-2-METHYLPHENOL;3-HYDROXY-4-METHYLANILINE;2M5AP;JAROCOL 2M5AP;5-AMINO-ORTHO-CRESOL;2-hydroxy-p-toluidine;4-AMINO-2-HRYDROXYTOLUENE;Rodol PAOC;5- aMinocresol
- CBNumber:
- CB5116645
- Molecular Formula:
- C7H9NO
- Molecular Weight:
- 123.15
- MDL Number:
- MFCD00043922
- MOL File:
- 2835-95-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Amino-2-methylphenol analytical standard | 93886 | 100 mg | $68.9 |
| 5-Amino-2-methylphenol 97% | 225088 | 5g | $86.4 |
| 5-Amino-2-methylphenol 97% | 225088 | 25g | $92.8 |
| 5-Amino-o-cresol >98.0%(T) | A0925 | 25g | $46 |
| 5-Amino-o-cresol >98.0%(T) | A0925 | 500g | $592 |
| More product size | |||
| Melting point | 160-162 °C(lit.) |
|---|---|
| Boiling point | 229.26°C (rough estimate) |
| Density | 1.0877 (rough estimate) |
| vapor pressure | 0.002Pa at 25℃ |
| refractive index | 1.5380 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| pka | 10.36±0.10(Predicted) |
| color | Pale brown |
| Water Solubility | 4.11g/L at 20℃ |
| BRN | 2802317 |
| Cosmetics Ingredients Functions | HAIR DYEING |
| Cosmetic Ingredient Review (CIR) | 5-Amino-o-cresol (2835-95-2) |
| InChI | 1S/C7H9NO/c1-5-2-3-6(8)4-7(5)9/h2-4,9H,8H2,1H3 |
| InChIKey | DBFYESDCPWWCHN-UHFFFAOYSA-N |
| SMILES | Cc1ccc(N)cc1O |
| LogP | 0.53 at 20℃ |
| CAS DataBase Reference | 2835-95-2(CAS DataBase Reference) |
| EWG's Food Scores | 3-5 |
| FDA UNII | UBB8XEB10B |
| EPA Substance Registry System | 5-Amino-2-methylphenol (2835-95-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | SJ6090000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29222990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Hazardous Substances Data | 2835-95-2(Hazardous Substances Data) | |||||||||
| Toxicity | bird - domestic,LD50,oral,562mg/kg (562mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
5-Amino-o-cresol price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93886 | 5-Amino-2-methylphenol analytical standard | 2835-95-2 | 100 mg | $68.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 225088 | 5-Amino-2-methylphenol 97% | 2835-95-2 | 5g | $86.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 225088 | 5-Amino-2-methylphenol 97% | 2835-95-2 | 25g | $92.8 | 2026-04-30 | Buy |
| TCI Chemical | A0925 | 5-Amino-o-cresol >98.0%(T) | 2835-95-2 | 25g | $46 | 2026-04-30 | Buy |
| TCI Chemical | A0925 | 5-Amino-o-cresol >98.0%(T) | 2835-95-2 | 500g | $592 | 2026-04-30 | Buy |
5-Amino-o-cresol Chemical Properties,Uses,Production
Application
2-Methyl-5-aminophenol is a well-known intermediate among many phenol derivatives. Due to its good biological activity, it is often used as an important raw material or intermediate in the synthesis of pharmaceuticals and pesticides, playing an important role in the synthesis of phenolic drugs.
Chemical Properties
Beige crystals
Uses
The spectrophotometric course of the reaction of 5-amino-2-methylphenol with p-benzoquinone di-imine was studied.
General Description
Brown powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
5-Amino-o-cresol reacts with strong oxidizing agents.
Fire Hazard
Flash point data are not available for 5-Amino-o-cresol, but 5-Amino-o-cresol is probably combustible.
Flammability and Explosibility
Not classified
Synthesis
95-74-9
2835-95-2
General procedure for the synthesis of 2-methyl-5-aminophenol from 3-chloro-4-methylaniline: 1700 kg of 50% sodium hydroxide solution was added to a 4800 L autoclave, followed by 1850 kg of ethanol solution containing 1000 kg of 3-chloro-4-methylaniline. Then 50kg of cuprous chloride and 15kg of copper powder were added as catalyst. The reaction vessel was sealed and replaced with nitrogen five times to ensure an oxygen-free environment. The reaction mixture was heated to 175°C and maintained at this temperature for 4 hours, during which time it was sampled and analyzed to monitor the progress of the reaction. Upon completion of the reaction, the mixture was cooled to room temperature. Ethanol was recovered under reduced pressure and then the reaction mixture was filtered and transferred to an 8000 L tank. The pH was adjusted to weak acidity by adding 1450 kg of industrial hydrochloric acid to the filtrate. Extraction was carried out with 2000L of ethyl acetate for three times. The organic phases were combined and the ethyl acetate was recovered by distillation under reduced pressure to obtain the crude product. To the crude product, 1000kg of ethanol was added, heated to 60°C to dissolve, and then 50kg of activated carbon was added to decolorize. After stirring for 1 hour, the activated carbon was removed by hot filtration and the filtrate was cooled to 5°C for crystallization. Finally, 707kg of 2-methyl-5-aminophenol was obtained with a yield of 85.36% and a purity of 99.8%.
References
[1] Patent: CN107963974, 2018, A. Location in patent: Paragraph 0030-0032; 0036; 0037
5-Amino-o-cresol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taixing Foreign Trade Nanjing Co., Ltd. | +86-025-83346564; +8613182976929 | sales@tx-chem.com | China | 125 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Shandong Juchuang Chemical Co., LTD | +16837774622 | admin@juchuangchem.com | China | 295 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
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View Lastest Price from 5-Amino-o-cresol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | 5-Amino-o-cresol
2835-95-2
|
1KG | 99%HPLC | 10 TONS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-28 | 5-Amino-O-Cresol
2835-95-2
|
$1.00 | 10kg | 99 % | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-05-15 | 5-Amino-o-cresol
2835-95-2
|
$30.00 | 1KG | 99% | 1 ton | Baoji Guokang Healthchem Co., Ltd. |
-
- 5-Amino-o-cresol
2835-95-2
- 99%HPLC
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5-Amino-O-Cresol
2835-95-2
- $1.00
- 99 %
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 5-Amino-o-cresol
2835-95-2
- $30.00
- 99%
- Baoji Guokang Healthchem Co., Ltd.
