ChemicalBook >> CAS DataBase List >>Methyl 3-amino-2-thiophenecarboxylate
Methyl 3-amino-2-thiophenecarboxylate
- CAS No.
- 22288-78-4
- Chemical Name:
- Methyl 3-amino-2-thiophenecarboxylate
- Synonyms
- METHYL 3-AMINOTHIOPHENE-2-CARBOXYLATE;3-aminothiophene-2-carboxylate;M3AT2C;AKOS 92421;ina-5545-2;Methyl3-am;AKOS B020093;Methyl 3-amino-2-;3-Amino-2-thenoate;RARECHEM AM UC 0123
- CBNumber:
- CB5123399
- Molecular Formula:
- C6H7NO2S
- Molecular Weight:
- 157.19
- MDL Number:
- MFCD00009765
- MOL File:
- 22288-78-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 02:15:01
| Product description | Number | Pack Size | Price |
| Methyl 3-amino-2-thiophenecarboxylate 99% | 232904 | 50g | $233 |
| Methyl 3-amino-2-thiophenecarboxylate 99% | 232904 | 10g | $43.15 |
| Methyl 3-Amino-2-thiophenecarboxylate >98.0%(GC)(T) | A1039 | 25g | $46 |
| Methyl 3-Amino-2-thiophenecarboxylate >98.0%(GC)(T) | A1039 | 100g | $142 |
| 3-Amino-2-methoxycarbonylthiophene | 423702 | 5g | $403 |
| More product size | |||
| Melting point | 62-64 °C (lit.) |
|---|---|
| Boiling point | 100-102 °C/0.1 mmHg (lit.) |
| Density | 1.274 (estimate) |
| refractive index | 1.5500 (estimate) |
| Flash point | 100-102°C/0.1mm |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in alcohol, toluene, xylene and other solvents |
| form | Fine Crystalline Powder |
| pka | 1.86±0.10(Predicted) |
| color | Beige to beige-brown |
| Water Solubility | Slightly soluble in water. |
| BRN | 1365614 |
| InChI | InChI=1S/C6H7NO2S/c1-9-6(8)5-4(7)2-3-10-5/h2-3H,7H2,1H3 |
| InChIKey | TWEQNZZOOFKOER-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)SC=CC=1N |
| CAS DataBase Reference | 22288-78-4(CAS DataBase Reference) |
| FDA UNII | E7S8G23AHX |
| EPA Substance Registry System | 2-Thiophenecarboxylic acid, 3-amino-, methyl ester (22288-78-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36/37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XM8347500 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Methyl 3-amino-2-thiophenecarboxylate price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 232904 | Methyl 3-amino-2-thiophenecarboxylate 99% | 22288-78-4 | 50g | $233 | 2026-04-30 | Buy |
| Sigma-Aldrich | 232904 | Methyl 3-amino-2-thiophenecarboxylate 99% | 22288-78-4 | 10g | $43.15 | 2025-07-31 | Buy |
| TCI Chemical | A1039 | Methyl 3-Amino-2-thiophenecarboxylate >98.0%(GC)(T) | 22288-78-4 | 25g | $46 | 2026-04-30 | Buy |
| TCI Chemical | A1039 | Methyl 3-Amino-2-thiophenecarboxylate >98.0%(GC)(T) | 22288-78-4 | 100g | $142 | 2026-04-30 | Buy |
| Usbiological | 423702 | 3-Amino-2-methoxycarbonylthiophene | 22288-78-4 | 5g | $403 | 2026-06-03 | Buy |
Methyl 3-amino-2-thiophenecarboxylate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
Methyl 3-amino-2-thiophenecarboxylate was used in:
- the synthesis of 4-nitro and 4-aminothienyl ureas
- total synthesis of quinazolinocarboline alkaloids
- preparation of thienopyrimidinone analogs
Uses
Methyl 3-amino-2-thiophenecarboxylate is the starting material for synthesising Belvarafenib. Belvarafenib is a small-molecule RAF dimer (type II) inhibitor with potential antitumour activity.
General Description
Methyl 3-amino-2-thiophenecarboxylate reacts with hydrazonoyl chlorides in the presence of triethylamine to yield corresponding N-arylamidrazones.
Safety
Methyl 3-amino-2-thiophenecarboxylate is irritating to the eyes and skin. Contact may cause skin irritation and severe eye irritation. Inhalation may cause respiratory irritation.
Synthesis of Methyl 3-amino-2-thiophenecarboxylate from Methyl thioglycolate and 2-Chloroacrylonitrile
Methyl 3-amino-2-thiophenecarboxylate Preparation Products And Raw materials
Raw materials
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Preparation Products
2,4-DICHLOROTHIENO[3,2-D]PYRIMIDINE
3-(Acetylamino)thiophene-2-carboxylic acid
3-(1H-PYRROL-1-YL)THIOPHENE-2-CARBOXYLIC ACID
2,4-Dichlorothieno[3,2-d]pyrimidine
Methyl 3-aminosulfonylthiophene-2-carboxylate
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Global( 473)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xinxiang Hongqi District Houyuan Trading Co.,Ltd | +86-0373-3695376 +86-13937349994 | HYJM@houyuanjm.com | China | 299 | 58 |
| GuiZhou DoSincerely biological technology Co.,Ltd. | +8613511983931 | 271622643@qq.com | China | 9 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
View Lastest Price from Methyl 3-amino-2-thiophenecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-05 | Methyl 3-amino-2-thiophenecarboxylate
22288-78-4
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-21 | Methyl 3-aminothiophene-2-carboxylate
22288-78-4
|
1KG | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | ||
 |
2026-04-27 | Methyl3-amino-2-thiophenecarboxylate
22288-78-4
|
1kg | 98% | 100tons | Shandong Vital Biotechnology Co., Ltd. |
-
- Methyl 3-amino-2-thiophenecarboxylate
22288-78-4
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Methyl 3-aminothiophene-2-carboxylate
22288-78-4
- $0.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Methyl3-amino-2-thiophenecarboxylate
22288-78-4
- 98%
- Shandong Vital Biotechnology Co., Ltd.
Methyl 3-amino-2-thiophenecarboxylate Spectrum
Methyl 3-amino-2-thiophenecarboxylate(22288-78-4)MSMethyl 3-amino-2-thiophenecarboxylate(22288-78-4)1HNMRMethyl 3-amino-2-thiophenecarboxylate(22288-78-4)13CNMRMethyl 3-amino-2-thiophenecarboxylate(22288-78-4)IR1Methyl 3-amino-2-thiophenecarboxylate(22288-78-4)IR2Methyl 3-amino-2-thiophenecarboxylate(22288-78-4)Raman
22288-78-4(Methyl 3-amino-2-thiophenecarboxylate )Related Search:
1of4
AMino-2-thiophenecarboxylate
AMino thiophene - 2-3 - carboxylic acid Methyl ester
Methyl3-aMino-2-thiophenecarbo
RARECHEM AM UC 0123
3-amino-2-thiophenecarboxylicacimethylester
ina-5545-2
Methyl3-amino-2-thenoate
3-AMINO-2-METHOXYCARBONYLTHIOPHENE
3-AMINO-2-THIOPHENECARBOXYLIC ACID METHYL ESTER
3-AMINOTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
AKOS 92421
AKOS B020093
ASINEX-REAG BAS 05504796
LABOTEST-BB LT00112337
M3AT2C
METHYL 3-AMINO-2-THIOPHENECARBOXYLATE
METHYL-3-AMINO-2-THIOPHENE FORMATE
METHYL 3-AMINO-2-THIOPHENECARBOXYLATE, 9 9%
Methyl 3-aminothiophene-2-carboxylate, 98+%
3-AMINO-2-THIOPHENE METHYLFORMATE
Name: 3-Aminothiophene-2-carboxylic acid methyl ester
Methyl-3-Aminothiophene-2-Carb
3-amino-2-thiophenecarboxylate
3-Aminothiophen-2-carboxylic acid methyl ester
Methyl 3-amino-2-thiophenecarboxylate ,98%
Methy1-3-amino-2-thiophene carboxylate
3-Amino-2-thenoate
Methyl 3-aminothiophene-2-carboxylate ,95%
Methyl 3-amino-2-thi
Methyl 3-aMino-2-thiophenecarboxylate, 99% 10GR
Methyl 3-aMino-2-thiophenecarboxylate, 99% 50GR
2-Methoxycarbonyl-3-aMino-thiophene
3-aMino-2-carboMethoxythiophene
3-aminothiophene-2-carboxyL
Methyl 3-amino-2-
Methyl3-am
Methyl 3-Amino-2-thiophenecarboxylate >
3-amino-2-carboxylate methyl thiophene
Methyl 3-amino-2-thiophenoate
Methyl 3-amino-2-thiophenecarboxylate USP/EP/BP
Methyl 3-aminothiophene-2-carboxylateQ: What is
Methyl 3-aminothiophene-2-carboxylate Q: What is the CAS Number of
Methyl 3-aminothiophene-2-carboxylate Q: What is the storage condition of
Methyl 3-aminothiophene-2-carboxylate Q: What are the applications of
Methyl 3-aminothiophene-2-carboxylate
Methyl-3-amino2-thiopene carboxylate
Methyl-3-aminothiophen-3-carboxylate
3-aminothiophene-2-carboxylate
METHYL 3-AMINOTHIOPHENE-2-CARBOXYLATE
22288-78-4
22288-74-4
C6H7NO2S
Heterocyclic Building Blocks
Thiophenes
Building Blocks
API intermediates
Thiophenes & Benzothiophenes
Pharmaceutical intermediate
Sulphur Derivatives
INTERMEDIATESOFTENOXICAM
Esters
Thiophenes & Benzothiophenes
