5-Carboxyindazole hydrochloride
- CAS No.
- 61700-61-6
- Chemical Name:
- 5-Carboxyindazole hydrochloride
- Synonyms
- 1H-INDAZOLE-5-CARBOXYLIC ACID;100287;5-(1H)INDAZOLE CARBOXYLIC ACID;5-Carboxy-1H-indazole;5-CARBOXYINDAZOLE HCL;1H-INDAZOLE-5-CARBOXYLATE;5-INDAZOLECARBOXYLIC ACID;INDAZOLE-5-CARBOXYLIC ACID;1H-Indazole-5-carboxylic ...;1H-5-indazolecarboxylic acid
- CBNumber:
- CB5140334
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD03426158
- MOL File:
- 61700-61-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1H-Indazole-5-carboxylic acid 97% | 702455 | 1g | $54.2 |
| 1H-Indazole-5-carboxylic acid ≥95% | OR60062 | 1g | $22 |
| 1H-Indazole-5-carboxylic acid ≥95% | OR60062 | 5g | $81 |
| 1H-Indazole-5-carboxylic acid ≥96%(HPLC) | 17915 | 1G | $22.03 |
| 1H-Indazole-5-carboxylic acid ≥96%(HPLC) | 17915 | 5G | $68.3 |
| More product size | |||
| Melting point | >250℃ |
|---|---|
| Boiling point | 443.7±18.0 °C(Predicted) |
| Density | 1.506±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 4.03±0.30(Predicted) |
| form | Spherical Beads |
| color | Yellow to amber |
| InChI | 1S/C8H6N2O2/c11-8(12)5-1-2-7-6(3-5)4-9-10-7/h1-4H,(H,9,10)(H,11,12) |
| InChIKey | MAVGBUDLHOOROM-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccc2[nH]ncc2c1 |
| CAS DataBase Reference | 61700-61-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P405-P501a-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
5-Carboxyindazole hydrochloride price More Price(74)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 702455 | 1H-Indazole-5-carboxylic acid 97% | 61700-61-6 | 1g | $54.2 | 2026-04-30 | Buy |
| Apolloscientific | OR60062 | 1H-Indazole-5-carboxylic acid ≥95% | 61700-61-6 | 1g | $22 | 2026-06-04 | Buy |
| Apolloscientific | OR60062 | 1H-Indazole-5-carboxylic acid ≥95% | 61700-61-6 | 5g | $81 | 2026-06-04 | Buy |
| Chem-Impex | 17915 | 1H-Indazole-5-carboxylic acid ≥96%(HPLC) | 61700-61-6 | 1G | $22.03 | 2026-05-19 | Buy |
| Chem-Impex | 17915 | 1H-Indazole-5-carboxylic acid ≥96%(HPLC) | 61700-61-6 | 5G | $68.3 | 2026-05-19 | Buy |
5-Carboxyindazole hydrochloride Chemical Properties,Uses,Production
Uses
1H-Indazole-5-carboxylic Acid is used as a reactant in the synthesis of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists.
Synthesis
473416-12-5
61700-61-6
General procedure for the synthesis of indazole-5-carboxylic acid hydrochloride from methyl 1H-indazole-5-carboxylate: 1H-indazole-5-carboxylic acid methyl ester (6.5 g, 1.0 eq.) and 200 mL of methanol (MeOH) were added to a stirred 1 L reaction flask, followed by a solution of sodium hydroxide (NaOH, 4.4 g, 3.0 eq.) dissolved in 150 mL of water (H2O). The reaction mixture was heated to reflux for 1 hour. Upon completion of the reaction, the organic solvent was evaporated under reduced pressure. The remaining aqueous phase was washed with ethyl acetate (EtOAc) and then acidified with 3N hydrochloric acid (HCl) to pH=5~6. The precipitate was collected by filtration and washed with deionized water to afford the target product, indazole-5-carboxylic acid hydrochloride, as a yellow solid (6.2 g, 98% yield).
References
[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0261
[2] Patent: US2012/277224, 2012, A1. Location in patent: Page/Page column 40
[3] Patent: WO2014/66743, 2014, A1. Location in patent: Paragraph 0146
[4] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8219 - 8248
5-Carboxyindazole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8740 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9545 | 58 |
View Lastest Price from 5-Carboxyindazole hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-12 | 1H-Indazole-5-carboxylic acid
61700-61-6
|
$34.00-282.00 | 25g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2021-07-02 | 1H-Indazole-5-carboxylic acid
61700-61-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-10 | 5-Carboxyindazole hydrochloride
61700-61-6
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- 1H-Indazole-5-carboxylic acid
61700-61-6
- $34.00-282.00
- 0.98
- Shanghai UCHEM Inc.
-
- 1H-Indazole-5-carboxylic acid
61700-61-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-Carboxyindazole hydrochloride
61700-61-6
- $1.00
- 98%
- Career Henan Chemical Co
61700-61-6(5-Carboxyindazole hydrochloride)Related Search:
1of4
