4'-Fluoro-2'-hydroxyacetophenone
- CAS No.
- 1481-27-2
- Chemical Name:
- 4'-Fluoro-2'-hydroxyacetophenone
- Synonyms
- 1-(4-Fluoro-2-hydroxyphenyl)ethan-1-one;1-(4-fluoro-2-hydroxyphenyl)ethanone;4-FLUORO-2-HYDROXYACETOPHENONE;4'-Fluoro-2'-hydroxy;4-FLUORO-2-HYDROXYACETOPHE;uoro-2'-hydroxyacetophenone;4-Fluoro-2-hydroxyacethophenone;4'-Fluoro-2'-hydroxyacetophenone;4'-Fluoro-2'-hydroxyacetophenone>4'-Fluoro-2'-hydroxyacetophenone98%
- CBNumber:
- CB5147045
- Molecular Formula:
- C8H7FO2
- Molecular Weight:
- 154.14
- MDL Number:
- MFCD00143203
- MOL File:
- 1481-27-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4′-Fluoro-2′-hydroxyacetophenone 98% | 466964 | 5g | $59.2 |
| 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) | F0723 | 5g | $67 |
| 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) | F0723 | 25g | $265 |
| 4'-Fluoro-2'-hydroxyacetophenone | FF36776 | 0.01kg | $150 |
| 4'-Fluoro-2'-hydroxyacetophenone | FF36776 | 0.025kg | $226.75 |
| More product size | |||
| Melting point | 32-34°C |
|---|---|
| Boiling point | 65°C 2mm |
| Density | 1.1850 (estimate) |
| Flash point | 98°C |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 9.17±0.10(Predicted) |
| form | powder to lump |
| color | White to Almost white |
| BRN | 2249799 |
| InChI | InChI=1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3 |
| InChIKey | HLTBTUXAMVOKIH-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC=C(F)C=C1O)C |
| CAS DataBase Reference | 1481-27-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29147000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4'-Fluoro-2'-hydroxyacetophenone price More Price(76)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 466964 | 4′-Fluoro-2′-hydroxyacetophenone 98% | 1481-27-2 | 5g | $59.2 | 2026-04-30 | Buy |
| TCI Chemical | F0723 | 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) | 1481-27-2 | 5g | $67 | 2026-04-30 | Buy |
| TCI Chemical | F0723 | 4'-Fluoro-2'-hydroxyacetophenone >97.0%(GC) | 1481-27-2 | 25g | $265 | 2026-04-30 | Buy |
| Biosynth | FF36776 | 4'-Fluoro-2'-hydroxyacetophenone | 1481-27-2 | 0.01kg | $150 | 2026-06-04 | Buy |
| Biosynth | FF36776 | 4'-Fluoro-2'-hydroxyacetophenone | 1481-27-2 | 0.025kg | $226.75 | 2026-06-04 | Buy |
4'-Fluoro-2'-hydroxyacetophenone Chemical Properties,Uses,Production
Chemical Properties
Colorless to yellow liquid
Uses
4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.
Preparation
Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%).
General Description
4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.
4'-Fluoro-2'-hydroxyacetophenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 4'-Fluoro-2'-hydroxyacetophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
![]() |
2019-09-02 | 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
|
$1.00 | 1KG | 98% | 200kg | Career Henan Chemical Co |
-

- 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 4'-Fluoro-2'-hydroxyacetophenone
1481-27-2
- $1.00
- 98%
- Career Henan Chemical Co
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