4-Piperidineethanol
- CAS No.
- 622-26-4
- Chemical Name:
- 4-Piperidineethanol
- Synonyms
- 2-(Piperidin-4-yl)ethan-1-ol;2-Piperidin-4-ylethanol;4-(2-HYDROXYETHYL)PIPERIDINE;4-Piperineethanol;4-ethanolpiperidine;4-PIPERIDINEETHANOL;piperidine-4-ethanol;PIPERIDIN-4-YLETHANOL;PIPERIDINEETHANOL(4-);Tirofiban Impurity 58
- CBNumber:
- CB5151899
- Molecular Formula:
- C7H15NO
- Molecular Weight:
- 129.2
- MDL Number:
- MFCD00006008
- MOL File:
- 622-26-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Piperidineethanol 97% | P46156 | 1g | $69 |
| 4-Piperidineethanol 97% | P46156 | 5g | $74 |
| 4-Piperidineethanol >96.0%(GC)(T) | P0992 | 5g | $53 |
| 4-Piperidineethanol >96.0%(GC)(T) | P0992 | 25g | $157 |
| 4-Piperidineethanol | TRC-P481960-25G | 25g | $1396 |
| More product size | |||
| Melting point | 46-47 °C (lit.) |
|---|---|
| Boiling point | 131-136 °C/17 mmHg (lit.) |
| Density | 1.0059 |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | 15.10±0.10(Predicted) |
| color | Brown |
| InChI | InChI=1S/C7H15NO/c9-6-3-7-1-4-8-5-2-7/h7-9H,1-6H2 |
| InChIKey | LDSQQXKSEFZAPE-UHFFFAOYSA-N |
| SMILES | N1CCC(CCO)CC1 |
| CAS DataBase Reference | 622-26-4(CAS DataBase Reference) |
| FDA UNII | VRR3T9QR54 |
| NIST Chemistry Reference | 4-Ethanolpiperidine(622-26-4) |
| EPA Substance Registry System | 4-Piperidineethanol (622-26-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Piperidineethanol price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P46156 | 4-Piperidineethanol 97% | 622-26-4 | 1g | $69 | 2023-06-20 | Buy |
| Sigma-Aldrich | P46156 | 4-Piperidineethanol 97% | 622-26-4 | 5g | $74 | 2023-01-07 | Buy |
| TCI Chemical | P0992 | 4-Piperidineethanol >96.0%(GC)(T) | 622-26-4 | 5g | $53 | 2026-04-30 | Buy |
| TCI Chemical | P0992 | 4-Piperidineethanol >96.0%(GC)(T) | 622-26-4 | 25g | $157 | 2026-04-30 | Buy |
| TRC | TRC-P481960-25G | 4-Piperidineethanol | 622-26-4 | 25g | $1396 | 2026-06-03 | Buy |
4-Piperidineethanol Chemical Properties,Uses,Production
Chemical Properties
white crystalline low melting solid
Uses
Reactant for synthesis of:• ;Ursolic acid derivatives1• ;Amodiaquine analogues for treatment of cerebral malaria2• ;Spiroimidazolidinone NPC1L1 inhibitors3• ;Piperazinyl glutamate pyridines as orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation4• ;Neurokinin-2 receptor antagonists5• ;Hepatitis C virus NS5B polymerase inhibitors6
Uses
4-Piperidineethanol have been used as an intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK
Uses
4-Piperidineethanol have been used as a intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK
Synthesis
51052-78-9
622-26-4
Lithium tetrahydroaluminum (0.06 mol) was added to ice-bath cooled anhydrous tetrahydrofuran (80 mL) under nitrogen protection, followed by the slow addition of crushed 4-piperidineacetic acid (4.95 g, 0.03 mol), and the temperature of the reaction was controlled to be no more than 30 °C. The reaction mixture was stirred at 25 °C overnight. Upon completion of the reaction, the system was cooled to 0 °C and water (3 mL), 30% aqueous sodium hydroxide solution (3 mL), and water (3 mL) were added sequentially and slowly dropwise. The resulting mixture was continued to be stirred at 25 °C for 30 min. Finally, the solvent was removed by distillation under reduced pressure to give 2.23 g of light yellow solid product in 62.5% yield.
References
[1] Patent: CN103755686, 2016, B. Location in patent: Paragraph 0099; 0100
4-Piperidineethanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 4-Piperidineethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 4-Piperidineethanol
622-26-4
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2022-02-22 | 2-(Piperidin-4-yl)ethanol
622-26-4
|
1KG | 99.5% | 100 tons | Honest Joy Holdings Limited
|
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 |
2019-07-06 | 4-Piperidineethanol
622-26-4
|
$1000.00 | 1KG | 98% | 1ton | Career Henan Chemical Co |
-
- 4-Piperidineethanol
622-26-4
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-(Piperidin-4-yl)ethanol
622-26-4
- $0.00
- 99.5%
- Honest Joy Holdings Limited
-
- 4-Piperidineethanol
622-26-4
- $1000.00
- 98%
- Career Henan Chemical Co
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