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ChemicalBook >> CAS DataBase List >>2,3-Dihydro-1-benzofuran-2-carboxylic acid

2,3-Dihydro-1-benzofuran-2-carboxylic acid

CAS No.
1914-60-9
Chemical Name:
2,3-Dihydro-1-benzofuran-2-carboxylic acid
Synonyms
AKOS BBS-00006837;2,3-Dihydro-2-benzofurancarboxylic Acid;2,3-dihydro-1-benzofuran-2-carboxylicaci;2,3-DIHYDRO-BENZOFURAN-2-CARBOXYLIC ACID;2-Benzofurancarboxylic acid, 2,3-dihydro-;2,3-Dihydrobenzo[b]furan-2-carboxylic acid;2,3-Dihydro-1-Benzofurane-2-CarboxylicAcid;2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID;(2-methyl-3-imidazo[1,2-a]pyridinyl)methanol;2,3-Dihydro-1-benzofuran-2-carboxylic acid, 2-Carboxy-2,3-dihydrobenzo[b]furan
CBNumber:
CB5295409
Molecular Formula:
C9H8O3
Molecular Weight:
164.16
MDL Number:
MFCD03086168
MOL File:
1914-60-9.mol
MSDS File:
SDS
Last updated:2026-05-28 02:29:42
Product description Number Pack Size Price
2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% OR23376 500mg $73
2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% OR23376 1g $82
2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% OR23376 5g $244
2,3-Dihydrobenzofuran-2-carboxylic acid 97%(HPLC) W4106 250mg $16
2,3-Dihydrobenzofuran-2-carboxylic acid 97%(HPLC) W4106 1g $33
More product size

2,3-Dihydro-1-benzofuran-2-carboxylic acid Properties

Melting point 116-118
Boiling point 340.5±31.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form solid
pka 3.17±0.20(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-51-22
Safety Statements  26-37/39
Hazard Note  Irritant
HS Code  29321900

2,3-Dihydro-1-benzofuran-2-carboxylic acid price More Price(86)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR23376 2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% 1914-60-9 500mg $73 2026-06-04 Buy
Apolloscientific OR23376 2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% 1914-60-9 1g $82 2026-06-04 Buy
Apolloscientific OR23376 2,3-Dihydrobenzo[b]furan-2-carboxylic acid ≥95% 1914-60-9 5g $244 2026-06-04 Buy
AK Scientific W4106 2,3-Dihydrobenzofuran-2-carboxylic acid 97%(HPLC) 1914-60-9 250mg $16 2026-06-04 Buy
AK Scientific W4106 2,3-Dihydrobenzofuran-2-carboxylic acid 97%(HPLC) 1914-60-9 1g $33 2026-06-04 Buy
Product number Packaging Price Buy
OR23376 500mg $73 Buy
OR23376 1g $82 Buy
OR23376 5g $244 Buy
W4106 250mg $16 Buy
W4106 1g $33 Buy

2,3-Dihydro-1-benzofuran-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

This compound is the starting material in the synthesis of (dihydro)benzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 24, p. 495, 1987 DOI: 10.1002/jhet.5570240236

Synthesis

Benzofuran-2-carboxylic acid

496-41-3

2,3-Dihydro-1-benzofuran-2-carboxylic acid

1914-60-9

a) Synthesis of (R,S)-2,3-dihydro-benzofuran-2-carboxylic acid (54a): commercially available benzofuran-2-carboxylic acid (Aldrich Chemical Company, 27 g, 167.7 mmol) was dissolved in ethyl acetate (300 mL). The hydrogenation reaction was catalyzed by 10% Pd/C (20 g) at 65-70 psi hydrogen pressure for 2 days. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated. A solvent mixture of ethyl acetate-hexane (1:6) was added to the residue for recrystallization. Filtration afforded benzodihydrofuran-2-carboxylic acid as a crystalline solid (20.23 g, 74% yield). Melting point: 116-117 °C. 1H NMR (300 MHz, CDCl3) δ: 11.05 (brs, 1H), 7.17 (m, 2H), 6.91 (m, 2H), 5.24 (dd, 1H), 3.63 (dd, 1H), 3.42 (dd, 1H).

References

[1] Patent: US2005/54630, 2005, A1. Location in patent: Page/Page column 42
[2] Justus Liebigs Annalen der Chemie, 1883, vol. 216, p. 169
[3] Chemische Berichte, 1906, vol. 39, p. 496
[4] Farmaco, 1998, vol. 53, # 12, p. 764 - 772
[5] Patent: US2008/200540, 2008, A1. Location in patent: Page/Page column 18

496-41-3
1914-60-9
Synthesis of 2,3-Dihydro-1-benzofuran-2-carboxylic acid from Benzofuran-2-carboxylic acid
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View Lastest Price from 2,3-Dihydro-1-benzofuran-2-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3-Dihydro-1-benzofuran-2-carboxylic acid pictures 2019-07-06 2,3-Dihydro-1-benzofuran-2-carboxylic acid
1914-60-9
$1.00 1KG 98% 1kg,5kg,100kg Career Henan Chemical Co

2,3-Dihydro-1-benzofuran-2-carboxylic acid Spectrum

2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID 2,3-DIHYDRO-BENZOFURAN-2-CARBOXYLIC ACID AKOS BBS-00006837 2,3-Dihydro-1-Benzofurane-2-CarboxylicAcid 2,3-Dihydrobenzo[b]furan-2-carboxylic acid 2-Benzofurancarboxylic acid, 2,3-dihydro- 2,3-Dihydro-1-benzofuran-2-carboxylic acid, 2-Carboxy-2,3-dihydrobenzo[b]furan (2-methyl-3-imidazo[1,2-a]pyridinyl)methanol 2,3-dihydro-1-benzofuran-2-carboxylicaci 2,3-Dihydro-2-benzofurancarboxylic Acid 1914-60-9 CARBOXYLIC ACID Benzodiozoles, Benzodioxines & Benzodioxepines Carboxylic Acids Benzodiozoles, Benzodioxines & Benzodioxepines Carboxylic Acids
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