7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
- CAS No.
- 779-27-1
- Chemical Name:
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
- Synonyms
- 7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID;RARECHEM AL BO 2319;OTAVA-BB BB7015592710;3-CARBOXY-7-HYDROXYCOUMARIN;7-hydroxy-3-carboxycoumarin;UMBELLIFERONE-3-CARBOXYLIC ACID;7-HYDROXYCOUMARIM-3-CARBOXYLIC ACID;7-Hydroxycoumarin-3-carboxylicAcid>7-Hydroxycoumarin-3-carboxylic acid ,98%;7-hydroxy-2-oxochromene-3-carboxylic acid
- CBNumber:
- CB5496161
- Molecular Formula:
- C10H6O5
- Molecular Weight:
- 206.15
- MDL Number:
- MFCD00017491
- MOL File:
- 779-27-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 7-Hydroxycoumarin-3-carboxylic acid suitable for fluorescence, ≥98.0% (TLC) | 55155 | 100MG | $320 |
| 7-Hydroxycoumarin-3-carboxylic Acid >98.0%(HPLC) | H1352 | 200mg | $119 |
| 7-Hydroxycoumarin-3-carboxylic Acid >98.0%(HPLC) | H1352 | 1g | $413 |
| Umbelliferone-3-carboxylic acid | FU66533 | 500mg | $275 |
| Umbelliferone-3-carboxylic acid | FU66533 | 1000mg | $510 |
| More product size | |||
| Melting point | 261 °C(lit.) |
|---|---|
| Boiling point | 474.8±45.0 °C(Predicted) |
| Density | 1.639±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: soluble |
| form | powder to crystal |
| pka | 7.04 ± 0.02, temperature: 23 °C |
| color | Yellow solid;Orange solid; Off-white powder |
| λmax | 386 nm (Buffer pH 10.0); 339 nm (Buffer pH 4.0) |
| BRN | 384141 |
| Major Application | Carbon-dioxide sensor; chemical sensors based on non-linear optics; monitoring of cationic photopolymerization processes; nanomaterials |
| Biological Applications | Chemical dosimeter for radiation therapy; detecting bacteria; detecting/sensing hydroxyl radicals; studying nucleic acids; as a substrate for measuring carboxylesterases activity, cellulases activity, β-galactosidases activity, glycosidases activity, glycosyltransferases activity, hydrolases activity, 4-hydroxycinnamate decarboxylases activity, β-lactamases activity, phosphatases activity, sulfatases activity; treating cancer/antitumor activity |
| InChI | InChI=1S/C10H6O5/c11-6-2-1-5-3-7(9(12)13)10(14)15-8(5)4-6/h1-4,11H,(H,12,13) |
| InChIKey | LKLWLDOUZJEHDY-UHFFFAOYSA-N |
| SMILES | C1(=O)OC2=CC(O)=CC=C2C=C1C(O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| HS Code | 29329990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 55155 | 7-Hydroxycoumarin-3-carboxylic acid suitable for fluorescence, ≥98.0% (TLC) | 779-27-1 | 100MG | $320 | 2026-04-30 | Buy |
| TCI Chemical | H1352 | 7-Hydroxycoumarin-3-carboxylic Acid >98.0%(HPLC) | 779-27-1 | 200mg | $119 | 2026-04-30 | Buy |
| TCI Chemical | H1352 | 7-Hydroxycoumarin-3-carboxylic Acid >98.0%(HPLC) | 779-27-1 | 1g | $413 | 2026-04-30 | Buy |
| Biosynth | FU66533 | Umbelliferone-3-carboxylic acid | 779-27-1 | 500mg | $275 | 2026-06-04 | Buy |
| Biosynth | FU66533 | Umbelliferone-3-carboxylic acid | 779-27-1 | 1000mg | $510 | 2026-06-04 | Buy |
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
Light yellow powder
Uses
Suitable as pH-indicator.
Uses
7-Hydroxycoumarin-3-carboxylic acid is a pH-indicator that can be immobilized on a support to give a pH sensor.
Synthesis
6093-71-6
779-27-1
General procedure for the synthesis of 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylic acid from ethyl 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylate: ethyl 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylate (2.00 g, 8.55 mmol) was dissolved in water (20 ml) at 90 °C and concentrated hydrochloric acid (6 ml) was added slowly. The reaction mixture was refluxed for 8 hours. After the reaction was completed, the reaction solution was cooled to room temperature, the precipitate was collected by filtration and washed with cold water to obtain 7-hydroxy-2-oxo-2H-benzopyran-3-carboxylic acid (1.32 g, 6.41 mmol) as a light red solid in 75% yield.
References
[1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986, vol. 25, p. 638 - 639
[2] Food Chemistry, 2012, vol. 135, # 4, p. 2872 - 2878
[3] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 5, p. 502 - 506
[4] Chemical Communications, 2017, vol. 53, # 11, p. 1813 - 1816
[5] Patent: CN106279125, 2017, A. Location in patent: Paragraph 0041; 0042
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jiangxi Lotchem Co.,Ltd. | +8615270827708 | lancetu@jxlotchem.com | CHINA | 338 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8740 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 21157 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9070 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
View Lastest Price from 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2021-07-13 | 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
779-27-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
