GRAMICIDIN A
- CAS No.
- 11029-61-1
- Chemical Name:
- GRAMICIDIN A
- Synonyms
- GA;LGA;hLGA;GLS2;GRAMICIDIN A;GRIMICIDIN A;α-fetoprotein，AFP;GRAMICIDIN A USP/EP/BP;Alpha Foetoprotein,AFP;Alphafoetoprotein, Human
- CBNumber:
- CB5669868
- Molecular Formula:
- C99H140N20O17
- Molecular Weight:
- 1882.29
- MDL Number:
- MFCD00466944
- MOL File:
- 11029-61-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Gramicidin A from Bacillus brevis ≥90% (HPLC) | 50845 | 100mg | $1580 |
| Gramicidin A, High Purity, | 368020 | 25mg | $445 |
| Gramicidin A ≥90% | 26384 | 1mg | $36 |
| Gramicidin A ≥90% | 26384 | 5mg | $110 |
| Gramicidin A ≥90% | 26384 | 10mg | $203 |
| More product size | |||
| storage temp. | 2-8°C |
|---|---|
| solubility | ethanol: soluble |
| form | White to off-white solid |
| color | colorless or white |
| BRN | 6461131 |
| Sequence | {For}-Val-Gly-Ala-{D-Leu}-Ala-{D-Val}-Val-{D-Val}-Trp-{D-Leu}-Trp-{D-Leu}-Trp-{D-Leu}-Trp-{NHCH2CH2OH} |
| InChIKey | ZWCXYZRRTRDGQE-LUPIJMBPSA-N |
| EWG's Food Scores | 1 |
| FDA UNII | ST8MYP8LLG |
| UNSPSC Code | 51283112 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MD8230000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,60mg/kg (60mg/kg),"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 240, 1980. | |||||||||
| NFPA 704 |
|
GRAMICIDIN A price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 50845 | Gramicidin A from Bacillus brevis ≥90% (HPLC) | 11029-61-1 | 100mg | $1580 | 2026-04-30 | Buy |
| Sigma-Aldrich | 368020 | Gramicidin A, High Purity, | 11029-61-1 | 25mg | $445 | 2026-04-30 | Buy |
| Cayman Chemical | 26384 | Gramicidin A ≥90% | 11029-61-1 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 26384 | Gramicidin A ≥90% | 11029-61-1 | 5mg | $110 | 2026-04-30 | Buy |
| Cayman Chemical | 26384 | Gramicidin A ≥90% | 11029-61-1 | 10mg | $203 | 2026-04-30 | Buy |
GRAMICIDIN A Chemical Properties,Uses,Production
Uses
Gramicidin A is an effective antibiotic against Gram positive organisms.
Biological Activity
Cell permeable: no', 'Primary Target
Causes the formation of a monovalent cation-selective ion channel', 'Product does not compete with ATP.', 'Reversible: no
in vivo
Gramicidin A (0.11 mg/kg; intratumoral injection; twice weekly for 14 days) inhibits the growth of RCC tumor xenografts[2].
Gramicidin A (0.22 mg/kg; intratumoral injection; thrice weekly for 26 days) inhibits the growth and angiogenesis of VHL-expressing RCC tumor xenografts[3].
| Animal Model: | Female hairless Nu/J mice, 6- to 8-week old, injected subcutaneously with a suspension of SN12C cells (1.0 × 106) in a 50% growth factor–reduced Matrigel solution[2] |
| Dosage: | 0.11 mg/kg body weight |
| Administration: | Intratumoral injection, twice weekly for 14 days |
| Result: | The average tumor mass was reduced by approximately 40% without significant toxicity. |
| Animal Model: | Female hairless 6- to 8-week-old Nu/J mice, injected subcutaneously with a suspension of Caki-1-td-Tomato cells (1.5 × 106) in a 50% growth factor-reduced Matrigel solution[3]. |
| Dosage: | 0.22 mg/kg |
| Administration: | Intratumoral injection, thrice weekly for 26 days |
| Result: | Inhibited tumor growth. HIF-2α and GAPDH protein expression was substantially reduced. |
Purification Methods
Purify gramicidin A by countercurrent distribution from *C6H6/CHCl3, MeOH/H2O (15:15:23:7) with 5000 tubes. Fractions are examined by UV (280nm) of small aliquots. Separation from gramicidin C and other material occurred after 999 transfers. [Gross & Witkop Biochemistry 4 2495 1965, Bauer et al. Biochemistry 11 3266 1972.] Purify it finally by recrystallisation from EtOH/H2O and dry it at 100o/10-2mm over KOH. It forms platelets m 229-230o. It is almost insoluble in H2O (0.6%) but soluble in lower alcohols, dry Me2CO, dioxane, acetic acid and pyridine. The commercial material is more difficult to crystallise than the synthetic compound. [Sarges & Witkop J Am Chem Soc 86 1861 1964, 87 2011, 2020 1965.] It has characteristic [] D20 +27.3o (c 1.3, MeOH) and UV max at 282nm ( 22,100). The N-carbamoyldeformyl gramicidine A precipitates from EtOAc/pet ether (b 40-60o). [Beilstein 26 III/IV 4273.]
GRAMICIDIN A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28011 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4785 | 55 |
| Hubei Jusheng Technology Co.,Ltd | 027-59599241 18871490274 | 1400878000@qq.com | China | 9538 | 58 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 |
View Lastest Price from GRAMICIDIN A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Gramicidin A
11029-61-1
|
$113.00-667.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-11-18 | GRAMICIDIN A USP/EP/BP
11029-61-1
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Gramicidin A
11029-61-1
- $113.00-667.00
- TargetMol Chemicals Inc.
-
- GRAMICIDIN A USP/EP/BP
11029-61-1
- $1.10
- 99.9%
- Dideu Industries Group Limited
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