4-Methoxy-2-nitrobenzoic acid
- CAS No.
- 33844-21-2
- Chemical Name:
- 4-Methoxy-2-nitrobenzoic acid
- Synonyms
- 2-NITRO-4-METHOXYBENZOIC ACID;RARECHEM AL BO 1421;2-Nitro-p-anisic Acid;4-METHOXY-2-NITROBENZOIC ACID;4-Methoxy-2-nitronbenzoic acid;Benzoic acid, 4-methoxy-2-nitro-;4-METHOXY-2-NITROBENZOIC ACID 98%;4-Carboxy-3-nitroanisole, 2-Nitro-p-anisic acid;4-Methoxy-2-nitrobenzoic acid ISO 9001:2015 REACH
- CBNumber:
- CB5675333
- Molecular Formula:
- C8H7NO5
- Molecular Weight:
- 197.14
- MDL Number:
- MFCD04972109
- MOL File:
- 33844-21-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Methoxy-2-nitrobenzoic acid 97% | 638722 | 1g | $40 |
| 4-Methoxy-2-nitrobenzoic acid 97% | 638722 | 5g | $156 |
| 4-Methoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | M2828 | 1g | $56 |
| 4-Methoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | M2828 | 5g | $167 |
| 4-METHOXY-2-NITROBENZOIC ACID 97% | 64121 | 5G | $21 |
| More product size | |||
| Melting point | 196.5-200.5 °C (lit.) |
|---|---|
| Boiling point | 372.9±27.0 °C(Predicted) |
| Density | 1.430±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 2.46±0.25(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | 1S/C8H7NO5/c1-14-5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11) |
| InChIKey | DVZBWONCSHFMMM-UHFFFAOYSA-N |
| SMILES | COc1ccc(C(O)=O)c(c1)[N+]([O-])=O |
| CAS DataBase Reference | 33844-21-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 2918999090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
|||||||||
| NFPA 704 |
|
4-Methoxy-2-nitrobenzoic acid price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 638722 | 4-Methoxy-2-nitrobenzoic acid 97% | 33844-21-2 | 1g | $40 | 2023-06-20 | Buy |
| Sigma-Aldrich | 638722 | 4-Methoxy-2-nitrobenzoic acid 97% | 33844-21-2 | 5g | $156 | 2023-06-20 | Buy |
| TCI Chemical | M2828 | 4-Methoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 33844-21-2 | 1g | $56 | 2026-04-30 | Buy |
| TCI Chemical | M2828 | 4-Methoxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 33844-21-2 | 5g | $167 | 2026-04-30 | Buy |
| AstaTech | 64121 | 4-METHOXY-2-NITROBENZOIC ACID 97% | 33844-21-2 | 5G | $21 | 2026-04-30 | Buy |
4-Methoxy-2-nitrobenzoic acid Chemical Properties,Uses,Production
Uses
4-Methoxy-2-nitrobenzoic acid can serve as a key step in chemical reactions for synthesizing certain drug molecules, or play a role in the synthesis of certain types of dyes, fragrances, and other chemicals.
Synthesis
17484-36-5
33844-21-2
Step 1: A mixed solution of 4-methyl-3-nitroanisole (3.6 g, 18 mmol) with potassium permanganate (10 g, 63 mmol) in 200 mL of water was refluxed for 24 hours. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble solids. The filtrate was acidified to pH 2 with 1 N hydrochloric acid and subsequently extracted with chloroform (3 x 50 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and filtered. The filtrate was concentrated under reduced pressure and the precipitate precipitated was collected to give 4-methoxy-2-nitrobenzoic acid in 80% yield.
References
[1] Patent: US5665719, 1997, A
[2] Journal of Organic Chemistry, 2018, vol. 83, # 15, p. 8092 - 8103
[3] Chemische Berichte, 1918, vol. 51, p. 14
[4] Patent: US4781750, 1988, A
4-Methoxy-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
View Lastest Price from 4-Methoxy-2-nitrobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 4-Methoxy-2-nitrobenzoic acid
33844-21-2
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2021-07-13 | 4-Methoxy-2-nitrobenzoic acid
33844-21-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
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2020-02-26 | 4-Methoxy-2-nitrobenzoic acid
33844-21-2
|
1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-

- 4-Methoxy-2-nitrobenzoic acid
33844-21-2
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 4-Methoxy-2-nitrobenzoic acid
33844-21-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- 4-Methoxy-2-nitrobenzoic acid
33844-21-2
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
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