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3,4-DIHYDROQUINOLIN-2(1H)-ONE

3,4-DIHYDROQUINOLIN-2(1H)-ONE structure

CAS No.: 553-03-7

Chemical Name:: 3,4-DIHYDROQUINOLIN-2(1H)-ONE

Synonyms: HYDROCARBOSTYRIL;3,4-DIHYDRO-1H-QUINOLIN-2-ONE;3,4-DIHYDRO-2(1H)-QUINOLINONE;3,4-Dihydro-2-quinolinone;1,2,3,4-Tetrahydroquinolin-2-one;2-OXO-1,2,3,4-TETRAHYDROQUINOLINE;inone;DIHYDROCARBOSTYRIL;dihydro-α-quinolone;3,4-Dihydrocarbostyril

CBNumber:: CB5772351

Molecular Formula:: C9H9NO

Molecular Weight:: 147.17

MDL Number:: MFCD00016722

MOL File:: 553-03-7.mol

MSDS File:: SDS

Last updated:2026-05-28 02:46:32

Product description	Number	Pack Size	Price
3,4-Dihydro-2(1H)-quinolinone 98%	415936	10g	$171
3,4-Dihydro-2(1H)-quinolinone 98%	415936	1g	$39.4
3,4-Dihydroquinolin-2(1H)-one ≥98%	31701	1g	$40
3,4-Dihydroquinolin-2(1H)-one ≥98%	31701	5g	$132
3,4-Dihydroquinolin-2(1H)-one ≥98%	31701	10g	$246
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3,4-DIHYDROQUINOLIN-2(1H)-ONE Properties

Melting point	165-167 °C (lit.)
Boiling point	267.28°C (rough estimate)
Density	1.1135 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
pka	14.76±0.20(Predicted)
form	Crystalline Powder
color	Off-white
Water Solubility	Slightly soluble in water.
Sensitive	Light Sensitive
Merck	13,4800
InChI	InChI=1S/C9H9NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-4H,5-6H2,(H,10,11)
InChIKey	TZOYXRMEFDYWDQ-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC=C2)CCC1=O
CAS DataBase Reference	553-03-7(CAS DataBase Reference)
FDA UNII	2CKG6TX32F
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS06

Signal word

Warning

Hazard statements

H301-H302-H315-H317-H319-H335

Precautionary statements

P280a-P301+P310a-P405-P501a-P261-P280-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38-43

Safety Statements

26-36/37

RIDADR

2811

WGK Germany

Hazard Note

Irritant

HazardClass

6.1(b)

PackingGroup

III

HS Code

29337900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

NFPA 704

	0
2		0

3,4-DIHYDROQUINOLIN-2(1H)-ONE price More Price(89)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	415936	3,4-Dihydro-2(1H)-quinolinone 98%	553-03-7	10g	$171	2023-06-20	Buy
Sigma-Aldrich	415936	3,4-Dihydro-2(1H)-quinolinone 98%	553-03-7	1g	$39.4	2023-01-07	Buy
Cayman Chemical	31701	3,4-Dihydroquinolin-2(1H)-one ≥98%	553-03-7	1g	$40	2026-04-30	Buy
Cayman Chemical	31701	3,4-Dihydroquinolin-2(1H)-one ≥98%	553-03-7	5g	$132	2026-04-30	Buy
Cayman Chemical	31701	3,4-Dihydroquinolin-2(1H)-one ≥98%	553-03-7	10g	$246	2026-04-30	Buy

Product number	Packaging	Price	Buy
415936	10g	$171	Buy
415936	1g	$39.4	Buy
31701	1g	$40	Buy
31701	5g	$132	Buy
31701	10g	$246	Buy

3,4-DIHYDROQUINOLIN-2(1H)-ONE Chemical Properties,Uses,Production

Chemical Properties

Off-white crystalline powder

Uses

3,4-Dihydro-2(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments.

Uses

3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.

Definition

ChEBI: 3,4-Dihydro-2(1H)-quinolinone is a member of quinolines.

Synthesis Reference(s)

Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
Tetrahedron Letters, 36, p. 125, 1995 DOI: 10.1016/0040-4039(94)02191-D

General Description

Series of 3,4-dihydro-2(1H)-quinolinone derivatives having sigma-1 receptor (σ1R) antagonist activity have been synthesized. 3,4-dihydro-2((1)H)-quinolinones have been synthesized using N-(1′-alkoxy)cyclopropyl-2-haloanilines as starting reagent. Cyclopropane ring expansion in the presence of palladium catalyst is the major step involved in the synthesis. Library of 3,4-dihydro-2(1H)-quinolinones have been synthesized through the rearrangement of β-lactam intermediates on the solid-phase

3,4-DIHYDROQUINOLIN-2(1H)-ONE synthesis

Synthesis of 3,4-DIHYDROQUINOLIN-2(1H)-ONE from 1-Indanone

3,4-DIHYDROQUINOLIN-2(1H)-ONE Preparation Products And Raw materials

Raw materials

N-BOC-3,4-Dihydro-2(1H)-quinolinone 3-CHLORO-N-PHENYLPROPANAMIDE 1-Indanone

Preparation Products

Cilostazol VESNARINONE 2-dioxaborolan-2-yl)quinolin-2(1H)-one 6,8-DINITRO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 6,8-Dichloro-3,4-dihydro-1H-quinolin-2-one

6,8-Dibromo-3,4-dihydroquinolin-2(1H)-one

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3,4-DIHYDROQUINOLIN-2(1H)-ONE Suppliers

Global( 199)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Hebei Zhanyao Biotechnology Co. Ltd	15369953316 +8615369953316	admin@zhanyaobio.com	China	2123	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	21169	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hebei Zhanyao Biotechnology Co. Ltd	58
Dideu Industries Group Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58

View Lastest Price from 3,4-DIHYDROQUINOLIN-2(1H)-ONE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	1,2,3,4-Tetrahydroquinolin-2-one 553-03-7	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2021-10-15	1,2,3,4-Tetrahydroquinolin-2-one 553-03-7	$10.00	1KG	99%	20 tons	Hebei Zhanyao Biotechnology Co. Ltd
2020-02-14	1,2,3,4-Tetrahydroquinolin-2-one 553-03-7	$1.00	1KG	99%	200kgs	Career Henan Chemical Co

1,2,3,4-Tetrahydroquinolin-2-one
553-03-7
$1.10
99.00%
Dideu Industries Group Limited

1,2,3,4-Tetrahydroquinolin-2-one
553-03-7
$10.00
99%
Hebei Zhanyao Biotechnology Co. Ltd

1,2,3,4-Tetrahydroquinolin-2-one
553-03-7
$1.00
99%
Career Henan Chemical Co

3,4-DIHYDROQUINOLIN-2(1H)-ONE Spectrum

3,4-DIHYDROQUINOLIN-2(1H)-ONE(553-03-7)IR

553-03-7(3,4-DIHYDROQUINOLIN-2(1H)-ONE)Related Search:

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Epiandrosterone acetate Dehydroepiandrosterone Dihydromyrcenol Quinclorac 3,4-Dihydro-7-(4-bromobutoxy)-2(1H)-quinolinone

7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE 3,4-DIHYDROQUINOLIN-2(1H)-ONE AURORA KA-3413 AURORA KA-6039 AURORA KA-5523

1-BUTYL-3-CHLORO-3-METHYL-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE 3-BENZYL-1-BUTYL-3-CHLORO-1,2,3,4-TETRAHYDROQUINOLINE-2,4-DIONE AURORA KA-3185

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DIHYDROCARBOSTYRIL 3,4-DIHYDRO-2(H)-QUINOLINE 3,4-DIHYDRO-2(1H)-QUINOLONE 2-OXO-1,3,4-TRIHYDROQUINOLINE dihydro-α-quinolone o-aminohydrocinnamic acid lactam 3,4-Dihydrocarbostyril 3,4-DIHYDRO-1H-QUINOLIN-2-ONE, 99+% 2-Oxo-1,2,3,4-tetrahydroquinoline, 3,4-Dihydrocarbostyril 3,4-Dihydroquinolin-2(1H)-one 97% 4-Dihydro-2(1H)-quinolinone 3,4-Dihydro-2-quinolone 1,2,3,4-Tetrahydro-2(1H)-quinolinone 1,2,3,4-Tetrahydro-2-oxoquinoline 1,2,3,4-Tetrahydroquinoline-2-one 3,4-Dihydro-2(1H)-quinolinone,98% 3,4-Dihydro-2(1H)-quinolinoneHydrocarbostyril 2(1H)-Quinolinone, 3,4-dihydro- 3,4-Dihydro-2(1H)-quinolinone, 97+% 3,4-Dihydro-2(1H)-quinolinone 98% 3,4-Dihydro-2(1H)-quinoL inone 1,2,3,4-Tetrahydroquinolin-2-one ISO 9001：2015 REACH 4-Tetrahydroquinolin-2-one 3,4-DIHYDRO-1H-QUINOLIN-2-ONE 3,4-DIHYDROQUINOLIN-2(1H)-ONE 3,4-Dihydro-2(1H)-quinolinone 1,2,3,4-Tetrahydroquinolin-2-one 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE 3,4-Dihydro-2-quinolinone 3,4-DIHYDRO-2(1H)-QUINOLINONE HYDROCARBOSTYRIL 553-03-7 C6H4CH2CH2CONH Building Blocks Quinolines Heterocyclic Building Blocks Quinolines, Isoquinolines & Quinoxalines Heterocycles pharmacetical API intermediates

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3,4-DIHYDROQUINOLIN-2(1H)-ONE

3,4-DIHYDROQUINOLIN-2(1H)-ONE Properties

SAFETY

Risk and Safety Statements

3,4-DIHYDROQUINOLIN-2(1H)-ONE price More Price(89)

3,4-DIHYDROQUINOLIN-2(1H)-ONE Chemical Properties,Uses,Production

Chemical Properties

Uses

Uses

Definition

Synthesis Reference(s)

General Description

3,4-DIHYDROQUINOLIN-2(1H)-ONE synthesis

3,4-DIHYDROQUINOLIN-2(1H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

3,4-DIHYDROQUINOLIN-2(1H)-ONE Suppliers

View Lastest Price from 3,4-DIHYDROQUINOLIN-2(1H)-ONE manufacturers

3,4-DIHYDROQUINOLIN-2(1H)-ONE Spectrum

553-03-7(3,4-DIHYDROQUINOLIN-2(1H)-ONE)Related Search: