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ChemicalBook >> CAS DataBase List >>(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

CAS No.
209414-27-7
Chemical Name:
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
Synonyms
(2S)-2-(2-aMino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol;Efavirenz IP Imp E;Efavirenz USP RC A;Efavirenz Impurity 5;Efavirenz IP Impurity E;Efavirenz Related CoMpound A;Efavirenz USP Related Compound A;(S)-2-(2-Amino-5-chlorophenyl)-4-cy;Efavirenz Impurity 5(Efavirenz IP Impurity E);(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr...
CBNumber:
CB5948781
Molecular Formula:
C13H11ClF3NO
Molecular Weight:
289.68
MDL Number:
MFCD09751012
MOL File:
209414-27-7.mol
MSDS File:
SDS
Last updated:2026-05-28 03:26:44
Product description Number Pack Size Price
Efavirenz Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material PHR2068 50mg $566
Efavirenz Related Compound A 1234125 20mg $1140
(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% AA002K5T 1g $39
(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% AA002K5T 5g $131
(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95+% CD12096937 1g $465
More product size

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Properties

Melting point 134-136°C
Boiling point 425.1±45.0 °C(Predicted)
Density 1.46
storage temp. 2-8°C(protect from light)
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 9.13±0.24(Predicted)
color White to Off-White
Major Application pharmaceutical
InChI 1S/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1
InChIKey KEMUGFRERPPUHB-LBPRGKRZSA-N
SMILES FC(F)(F)[C@@](O)(c2c(ccc(c2)Cl)N)C#CC1CC1
FDA UNII Z3E01963ZY
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  WGK 3
HS Code  2922199695
Storage Class 11 - Combustible Solids

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2068 Efavirenz Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 209414-27-7 50mg $566 2026-04-30 Buy
Sigma-Aldrich 1234125 Efavirenz Related Compound A 209414-27-7 20mg $1140 2026-04-30 Buy
aablocks AA002K5T (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% 209414-27-7 1g $39 2026-05-28 Buy
aablocks AA002K5T (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95% 209414-27-7 5g $131 2026-05-28 Buy
Crysdot CD12096937 (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 95+% 209414-27-7 1g $465 2026-05-27 Buy
Product number Packaging Price Buy
PHR2068 50mg $566 Buy
1234125 20mg $1140 Buy
AA002K5T 1g $39 Buy
AA002K5T 5g $131 Buy
CD12096937 1g $465 Buy

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of Efavirenz (E425000) impurity.

6746-94-7
154598-53-5
209414-27-7
Synthesis of (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol from Cyclopropylacetylene and 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Preparation Products And Raw materials

Global( 121)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 923 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15082 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19853 58

View Lastest Price from (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2025-09-25 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
$5.00 1KG 98% Henan Fengda Chemical Co., Ltd
	(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2019-07-06 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
$7.00 1kg 99% 100kg Career Henan Chemical Co
	(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol pictures 2019-07-06 (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
209414-27-7
$7.00 1kg 99% 100kg Career Henan Chemical Co
BenzeneMethanol,2-aMino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoroMethyl)-, (aS)- (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (E05) (2R)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (R)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL (S)-5-CHLORO-A-(CYCLOPROPYLETHYNYL)-2-AMINO-A-(TRIFLUOROMETHYL)BENZENE METHANOL Efavirenz Related Compound A (20 mg) ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol) Efavirenz Related CoMpound A (S)-1-(2-AMino-5-chlorophenyl)-1-(trifluoroMethyl)-3-cyclopropyl-2-propyn-1-ol (E6) (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol Efavirenz Impurity 5(Efavirenz IP Impurity E) (2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol Efavirenz IP Imp E 1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (S)-5-Chloro-Alpha-(Cyclopropylethynyl-2-Amino-Alpha-(Triflumethanolmethyl)-Benzenemethanol Efavirenz USP Related Compound A (S)-2-(2-Amino-5-chlorophenyl)-4-cy Benzenemethanol, 2-amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)- Efavirenz IP Impurity E Efavirenz Impurity 5 (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL (E05) CAS 209414-27-7 Efavirenz USP RC A Efavirenz Related Compound A/ Efavirenz IP Impurity E (Efavirenz Amino Alcohol/ Efavirenz amino carbinol) (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr... Efavirenz Related Compound A ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn- (1234125) (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 98% (alphaS)-2-Amino-5-chloro-alpha-(2-cyclopropylethynyl)-alpha-(trifluoromethyl)-benzenemethanol Efavirenz Impurity: (S)-2-(2-Amino-5-Chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol (2S)-2-(2-aMino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol 209414-27-7
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