2-Fluoro-4-Bromo-3-Picoline
- CAS No.
- 128071-79-4
- Chemical Name:
- 2-Fluoro-4-Bromo-3-Picoline
- Synonyms
- 4-Bromo-2-fluoro-3-methylpyridine;2-Fluoro-4-Bromo-3-Picoline;4-BROMO-2-FLUORO-3-METHYLPYRIDIN;2-Fluoro-4-bromo-3-methylpyridine;bromo-4 fluoro-2 methyl-3 pyridine;Pyridine, 4-bromo-2-fluoro-3-methyl-;2-Fluoro-4-Bromo-3-Picoline ISO 9001：2015 REACH
- CBNumber:
- CB61032949
- Molecular Formula:
- C6H5BrFN
- Molecular Weight:
- 190.01
- MDL Number:
- MFCD09839278
- MOL File:
- 128071-79-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Bromo-2-fluoro-3-methylpyridine 98% | PC445018 | 250mg | $25 |
| 4-Bromo-2-fluoro-3-methylpyridine 98% | PC445018 | 1g | $30 |
| 4-Bromo-2-fluoro-3-methylpyridine 98% | PC445018 | 5g | $134 |
| 4-Bromo-2-fluoro-3-methylpyridine 98% | PC445018 | 10g | $256 |
| 4-Bromo-2-fluoro-3-methylpyridine 98% | PC445018 | 25g | $583 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| RIDADR | UN1993 |
| HS Code | 2933399990 |
2-Fluoro-4-Bromo-3-Picoline price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC445018 | 4-Bromo-2-fluoro-3-methylpyridine 98% | 128071-79-4 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC445018 | 4-Bromo-2-fluoro-3-methylpyridine 98% | 128071-79-4 | 1g | $30 | 2026-06-04 | Buy |
| Apolloscientific | PC445018 | 4-Bromo-2-fluoro-3-methylpyridine 98% | 128071-79-4 | 5g | $134 | 2026-06-04 | Buy |
| Apolloscientific | PC445018 | 4-Bromo-2-fluoro-3-methylpyridine 98% | 128071-79-4 | 10g | $256 | 2026-06-04 | Buy |
| Apolloscientific | PC445018 | 4-Bromo-2-fluoro-3-methylpyridine 98% | 128071-79-4 | 25g | $583 | 2026-06-04 | Buy |
2-Fluoro-4-Bromo-3-Picoline Chemical Properties,Uses,Production
Uses
2-Fluoro-4-bromo-3-pyridine is an organic compound that is often used as an intermediate in chemical synthesis, especially in the synthesis of drugs and pesticides.
Synthesis
128071-98-7
74-88-4
128071-79-4
A solution of lithium diisopropylammonium (LDA, 2M, 8.5 mL) was added slowly and dropwise to a solution of 4-bromo-2-fluoropyridine (2 g, 11.3 mmol) in tetrahydrofuran (THF, 40 mL) at -78 °C. The reaction mixture was stirred continuously at -78 °C for 1 h, followed by dropwise addition of iodomethane (4.8 g, 34 mmol). After continued stirring at -78 °C for 1 h, the reaction mixture was allowed to slowly warm up to room temperature over a period of 1 h. The reaction was completed with the addition of iodomethane (4.8 g, 34 mmol). Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate (NaHCO3) solution, followed by the addition of an aqueous solution of ammonium chloride (NH4Cl, 50 mL) at 0 °C and extraction with ethyl acetate (EA, 60 mL x 3). The organic layers were combined, washed with brine (60 mL), dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, PE/EtOAc) to afford 2-fluoro-3-methyl-4-bromopyridine (1 g, 47% yield) as a yellow solid.1H-NMR (400 MHz, CDCl3) δppm: 2.35 (s, 3H), 7.36 (d, 1H), 7.86 (d, 1H).
References
[1] Patent: WO2017/221092, 2017, A1. Location in patent: Paragraph 00188
2-Fluoro-4-Bromo-3-Picoline Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluoro-4-Bromo-3-Picoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28291 | 58 |
View Lastest Price from 2-Fluoro-4-Bromo-3-Picoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 2-Fluoro-4-Bromo-3-Picoline
128071-79-4
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited |
-
- 2-Fluoro-4-Bromo-3-Picoline
128071-79-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
