4-Chlorobenzhydrol
- CAS No.
- 119-56-2
- Chemical Name:
- 4-Chlorobenzhydrol
- Synonyms
- Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
- CBNumber:
- CB6151432
- Molecular Formula:
- C13H11ClO
- Molecular Weight:
- 218.68
- MDL Number:
- MFCD00004491
- MOL File:
- 119-56-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Meclozine impurity B European Pharmacopoeia (EP) Reference Standard | Y0001310 | 15 mg | $127 |
| Meclizine Related Compound A pharmaceutical secondary standard, certified reference material | PHR3034 | 30MG | $535 |
| Meclizine Related Compound A United States Pharmacopeia (USP) Reference Standard | 1377010 | 15mg | $1390 |
| 4-Chlorobenzhydrol 98% | 124982 | 1g | $34.3 |
| 4-Chlorobenzhydrol >98.0%(GC) | C0989 | 25g | $32 |
| More product size | |||
| Melting point | 58-60 °C (lit.) |
|---|---|
| Boiling point | 150-151°C 2,6mm |
| Density | 1.1178 (rough estimate) |
| refractive index | 1.5260 (estimate) |
| Flash point | 150-151°C/2.6mm |
| storage temp. | 2-8°C |
| solubility | insoluble |
| pka | 13.34±0.20(Predicted) |
| form | solid |
| color | White to Off-White |
| Water Solubility | insoluble |
| BRN | 2050235 |
| InChI | 1S/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H |
| InChIKey | AJYOOHCNOXWTKJ-UHFFFAOYSA-N |
| SMILES | OC(c1ccccc1)c2ccc(Cl)cc2 |
| CAS DataBase Reference | 119-56-2(CAS DataBase Reference) |
| FDA UNII | V5V8VYQ65X |
| NIST Chemistry Reference | Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2) |
| EPA Substance Registry System | Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H412 | |||||||||
| Precautionary statements | P273-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29062990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Chlorobenzhydrol price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001310 | Meclozine impurity B European Pharmacopoeia (EP) Reference Standard | 119-56-2 | 15 mg | $127 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR3034 | Meclizine Related Compound A pharmaceutical secondary standard, certified reference material | 119-56-2 | 30MG | $535 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1377010 | Meclizine Related Compound A United States Pharmacopeia (USP) Reference Standard | 119-56-2 | 15mg | $1390 | 2026-04-30 | Buy |
| Sigma-Aldrich | 124982 | 4-Chlorobenzhydrol 98% | 119-56-2 | 1g | $34.3 | 2026-04-30 | Buy |
| TCI Chemical | C0989 | 4-Chlorobenzhydrol >98.0%(GC) | 119-56-2 | 25g | $32 | 2026-04-30 | Buy |
4-Chlorobenzhydrol Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .
Definition
ChEBI: P-Chlorobenzhydrol is a diarylmethane.
Preparation
Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).
4-Chlorobenzhydrol Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 4-Chlorobenzhydrol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-27 | 4-Chlorobenzhydrol
119-56-2
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
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2025-06-20 | 4-Chlorobenzhydrol
119-56-2
|
$10.00-30.00 | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
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2022-02-25 | 4-Chlorobenzhydrol
119-56-2
|
$99.00 | 1KG | 99% | 1 ton | Hong Kong Tiansheng New Material Trading Co., Ltd |
-

- 4-Chlorobenzhydrol
119-56-2
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 4-Chlorobenzhydrol
119-56-2
- $10.00-30.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-

- 4-Chlorobenzhydrol
119-56-2
- $99.00
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
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