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ChemicalBook >> CAS DataBase List >>N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE

CAS No.
76315-01-0
Chemical Name:
N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE
Synonyms
OTAVA-BB 1403921;N-Boc-N-benzyl-glycine;N-Benzyl-N-Cbz-glycine;N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE;N-α-(t-Butoxycarbonyl)-N-α-benzylglycine;2-(BENZYL(TERT-BUTOXYCARBONYL)AMINO)ACETIC ACID;(N-benzyl-N-tert-butoxycarbonyl)aminoacetic acid;2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid 95+%;Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-(phenylmethyl)-;2-[benzyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetic acid
CBNumber:
CB61518203
Molecular Formula:
C14H19NO4
Molecular Weight:
265.3
MDL Number:
MFCD02094473
MOL File:
76315-01-0.mol
MSDS File:
SDS
Last updated:2026-05-28 03:20:14
Product description Number Pack Size Price
N-Benzyl-N-Cbz-glycine ≥95% CS-W003991 1g $27
N-Benzyl-N-Cbz-glycine ≥95% CS-W003991 5g $73
N-Benzyl-N-Cbz-glycine ≥95% CS-W003991 10g $145
N-Benzyl-N-Cbz-glycine ≥95% CS-W003991 25g $240
2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid >98% OR318086 250mg $21
More product size

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Properties

Boiling point 409.5±34.0 °C(Predicted)
Density 1.170±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.01±0.10(Predicted)
form Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2921490090

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-W003991 N-Benzyl-N-Cbz-glycine ≥95% 76315-01-0 1g $27 2026-06-04 Buy
ChemScene CS-W003991 N-Benzyl-N-Cbz-glycine ≥95% 76315-01-0 5g $73 2026-06-04 Buy
ChemScene CS-W003991 N-Benzyl-N-Cbz-glycine ≥95% 76315-01-0 10g $145 2026-06-04 Buy
ChemScene CS-W003991 N-Benzyl-N-Cbz-glycine ≥95% 76315-01-0 25g $240 2026-06-04 Buy
Apolloscientific OR318086 2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid >98% 76315-01-0 250mg $21 2026-06-04 Buy
Product number Packaging Price Buy
CS-W003991 1g $27 Buy
CS-W003991 5g $73 Buy
CS-W003991 10g $145 Buy
CS-W003991 25g $240 Buy
OR318086 250mg $21 Buy

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Chemical Properties,Uses,Production

Uses

2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid is a Glycine (HY-Y0966) derivative[1].

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

Benzylaminoacetic acid hydrochloride

7689-50-1

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE

76315-01-0

N-benzylglycine hydrochloride (3 g, 14.88 mmol) and di-tert-butyl dicarbonate (3.25 g, 14.88 mmol) were reacted in dichloromethane (40 mL). Triethylamine (6.22 mL, 44.6 mmol) was added to the reaction system and stirred at room temperature for 6 days. Upon completion of the reaction, the reaction mixture was partitioned with dichloromethane and dilute hydrochloric acid and the organic phase was extracted with dichloromethane (3 x 20 mL). The organic layers were combined, washed sequentially with water (20 mL) and brine (20 mL) and dried over anhydrous magnesium sulfate. Concentration gave the target product N-BOC-N-benzylglycine (5 g, 125% yield) as a clear, colorless oil containing a small amount of triethylamine hydrochloride impurity. The product was characterized by 1H NMR (400 MHz, CDCl3): δ1.38-1.46 (d, 9H), 3.71 (s, 1H), 3.86 (s, 1H), 4.54 (d, J=12.38Hz, 2H), 7.07-7.37 (m, 5H). The product does not require further purification and can be used directly in the next reaction.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

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View Lastest Price from N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE pictures 2019-07-06 N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE
76315-01-0
$1.00 1KG 98% 200kg Career Henan Chemical Co
N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE 2-(BENZYL(TERT-BUTOXYCARBONYL)AMINO)ACETIC ACID OTAVA-BB 1403921 Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-(phenylmethyl)- N-Boc-N-benzyl-glycine tert-Butyl N-(2-hydroxy-2-oxoethyl)-N-(phenylmethyl)carbamate (N-benzyl-N-tert-butoxycarbonyl)aminoacetic acid 2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid 95+% N-α-(t-Butoxycarbonyl)-N-α-benzylglycine 2-[benzyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetic acid N-Benzyl-N-Cbz-glycine 76315-01-0
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