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N-ME-AIB-OH HCL

N-ME-AIB-OH HCL structure

CAS No.: 2566-34-9

Chemical Name:: N-ME-AIB-OH HCL

Synonyms: MeAIB;2-(METHYLAMINO)ISOBUTYRIC ACID;N-ME-AIB-OH;H-MEAIB-OH;H-N-Me-Aib-OH;H-(ME)MEALA-OH;N-ME-AIB-OH HCL;N-Me-a-Me-Ala-OH;2,N-DIMETHYLALANINE;N,2-DIMETHYLALANINE

CBNumber:: CB6316473

Molecular Formula:: C5H11NO2

Molecular Weight:: 117.15

MDL Number:: MFCD00004191

MOL File:: 2566-34-9.mol

MSDS File:: SDS

Last updated:2026-06-12 16:21:36

Product description	Number	Pack Size	Price
α-(Methylamino)isobutyric acid ≥97% (titration)	M2383	250mg	$60.3
α-(Methylamino)isobutyric acid ≥97% (titration)	M2383	1g	$171
2-(Methylamino)isobutyric Acid Hydrate >98.0%(T)	M1388	1g	$65
2-(Methylamino)isobutyric Acid Hydrate >98.0%(T)	M1388	5g	$192
a-(Methylamino)isobutyric Acid (Neutral Amino Acid Transporter A Inhibitor, MeBIA) ≥98%(TLC)	217135	250mg	$453

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N-ME-AIB-OH HCL Properties

Melting point	300 °C
Boiling point	192.5±23.0 °C(Predicted)
Density	1.2000 (estimate)
refractive index	1.4650 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Water Solubility	almost transparency in Water
form	powder to crystal
pka	2.17±0.10(Predicted)
color	White to Almost white
BRN	1746984
InChI	1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
InChIKey	DLAMVQGYEVKIRE-UHFFFAOYSA-N
SMILES	CNC(C)(C)C(O)=O
FDA UNII	26F96C8MBJ
UNSPSC Code	12352209
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P305+P351+P338

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

HS Code

2922.49.8000

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

NFPA 704

	0
2		0

N-ME-AIB-OH HCL price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M2383	α-(Methylamino)isobutyric acid ≥97% (titration)	2566-34-9	250mg	$60.3	2026-04-30	Buy
Sigma-Aldrich	M2383	α-(Methylamino)isobutyric acid ≥97% (titration)	2566-34-9	1g	$171	2026-04-30	Buy
TCI Chemical	M1388	2-(Methylamino)isobutyric Acid Hydrate >98.0%(T)	2566-34-9	1g	$65	2026-04-30	Buy
TCI Chemical	M1388	2-(Methylamino)isobutyric Acid Hydrate >98.0%(T)	2566-34-9	5g	$192	2026-04-30	Buy
Usbiological	217135	a-(Methylamino)isobutyric Acid (Neutral Amino Acid Transporter A Inhibitor, MeBIA) ≥98%(TLC)	2566-34-9	250mg	$453	2026-06-03	Buy

Product number	Packaging	Price	Buy
M2383	250mg	$60.3	Buy
M2383	1g	$171	Buy
M1388	1g	$65	Buy
M1388	5g	$192	Buy
217135	250mg	$453	Buy

N-ME-AIB-OH HCL Chemical Properties,Uses,Production

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

α-(Methylamino)isobutyric acid (MeAIB) has been used:

as a system A transport system inhibitor to perform inhibition experiments
as a system A transport system inhibitor to study its effect on the generation of epileptiform field potentials (EFPs) in the acutely disinhibited cortical slices
as an N-acetyltransferase (SNAT) inhibitor in Hankμs balanced salt solution (HBSS) to study its influence on the uptake of 14C-cysteine/ radioactive-labeled cysteine

Definition

ChEBI: Alpha-(methylamino)isobutyric acid is a non-proteinogenic alpha-amino acid that is isobutyric acid in which the alpha-hydrogen has been replaced by a methylamino group. It has a role as a human urinary metabolite. It is an alanine derivative, a non-proteinogenic alpha-amino acid and a secondary amino compound. It is functionally related to an isobutyric acid. It is a conjugate acid of a N-methyl-aminoisobutyrate zwitterion.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 8120, 1995 DOI: 10.1021/jo00130a002

Biological Activity

α-(Methylamino)isobutyric acid (MeAIB), a competitive inhibitor of the neutral amino acid transport A system, is an N-methylated substrate. It is capable of decreasing the amplitude of the miniature excitatory postsynaptic current (mEPSC) in hippocampus neurons developing on top of astrocytes. MeAIB can block the alanine-proline (AP) pathway.

N-ME-AIB-OH HCL synthesis

Synthesis of N-ME-AIB-OH HCL from 2-Bromo-2-methylpropionic acid and Methylamine

N-ME-AIB-OH HCL Preparation Products And Raw materials

Raw materials

Methylamine hydrochloride POTASSIUM CYANIDE Methylamine Acetone 2-Bromo-2-methylpropionic acid

Preparation Products

2-Methyl-2-methylamino-propionamide

N-ME-AIB-OH HCL Suppliers

Global( 98)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30224	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49962	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33324	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
GL Biochem (Shanghai) Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58
HANGZHOU LEAP CHEM CO., LTD.	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from N-ME-AIB-OH HCL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-06-12	MeAIB 2566-34-9			99.89%	10g	TargetMol Chemicals Inc.

MeAIB
2566-34-9
$0.00
99.89%
TargetMol Chemicals Inc.

N-ME-AIB-OH HCL Spectrum

N-ME-AIB-OH HCL(2566-34-9)¹HNMR N-ME-AIB-OH HCL(2566-34-9)¹³CNMR N-ME-AIB-OH HCL(2566-34-9)IR1 N-ME-AIB-OH HCL(2566-34-9)Raman

2566-34-9(N-ME-AIB-OH HCL)Related Search:

N-Me-Ser-OH·HCl N-ME-PHG-OH N-ME-LYS(Z)-OH N-ME-D-PHG-OH 4-Anilino-1-benzyl-4-piperidinecarboxylic acid

1-BOC-3-AMINOPIPERIDINE 1-(Cbz-amino)cyclopropanecarboxylic acid N-ME-AIB-OH HCL Fmoc-Aib-OH Boc-Aib-OH

Z-AIB-OH METHYL BETA-(DIMETHYLAMINO)ISOBUTYRATE FMOC-AIB-OPFP FMOC-ACPC-OH DNP-ALPHA-AMINOISOBUTYRIC ACID

N-CARBAMYL-ALPHA-AMINO-ISOBUTYRIC ACID N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE DIETHYL 2-(ACETYLAMINO)-2-[4-(METHOXYCARBONYL)BENZYL]MALONATE

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N-ME-ALPHA-AMINOISOBUTYRIC ACID N-ME-ALPHA-ME-ALA-OH N-ME-AIB-OH HCL N-METHYL-ALPHA-AMINOISOBUTYRIC ACID N-METHYL-ALPHA-AMINOISOBUTYRIC ACID HYDROCHLORIDE N-METHYL-ALPHA-METHYL-ALANINE N-METHYL-ALPHA-METHYLALANINE HYDROCHLORIDE N,2-DIMETHYLALANINE 2,N-DIMETHYLALANINE 2-(METHYLAMINO)-2-METHYLPROPIONIC ACID ALPHA-(METHYLAMINO)ISOBUTYRIC ACID H-(ME)MEALA-OH H-MEAIB-OH A-(METHYLAMINO)ISOBUTYRIC ACID N-Methyl-a-aminoisobutyric acid 2-(METHYLAMINO)ISOBUTYRIC ACID HYDRATE 2-Methyl-2-(methylamino)propionic acid Methylaminoisobutanoic acid 2-(Methylamino)isobutyric acid,99% α-(Methylamino)isobutyric acid,2,N-Dimethylalanine, 2-(Methylamino)-2-methylpropionic acid N-Me-a-Me-Ala-OH N-METHYL-A-AMINOISOBUTYRIC ACID HYDROCHLORIDE 2-Methyl-2-(MethylaMino)propanoic acid hydrate N-Methyl-α-aminoisobutyric acid hydrochloride 2-(Methylamino)isobutyric Acid N,2-Dimethyl-DL-alanine 2-Methyl-2-(methylamino) N-Methyl-α-aminoisobutyric acid hydrochloride≥ 98% (TLC) N-Methyl-α-methylalanine hydrochloride 2,N-Dimethylalanine, 2-(Methylamino)-2-methylpropionic acid 2-Methyl-2-(methylamino)propanoic acid 2-(Methylamino)isobutyricAcidHydrate> Methylamino Hydrate Alanine, N,2-dimethyl- 2-methyl-2-(methylamino)propanoicaci H-N-Me-Aib-OH α-(Methylamino)isobutyric acid alpha-(Methylamino)isobutyric acid, Glutamine transport inhibitor 2-(METHYLAMINO)ISOBUTYRIC ACID MeAIB N-ME-AIB-OH 2566-34-9 CH3NHCCH32COOH C5H11NO2xH2O Biochemicals and Reagents Amino Acids and Peptides BioChemical Modified Amino Acids I - Z Peptide Synthesis N-Methyl Amino Acids Specialty Synthesis Unnatural Amino Acid Derivatives

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