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4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE structure

CAS No.: 1700-29-4

Chemical Name:: 4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE

Synonyms: 4-Benzyloxy-3-methoxybenzyl cyanide;4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE;4-(Benzyloxy)-3-methoxyphenylacetonitrile 98%;2-(4-(Benzyloxy)-3-Methoxyphenyl)acetonitrile;3-Methoxy-4-(Phenylmethoxy)-Benzeneacetonitrile;2-(3-methoxy-4-phenylmethoxyphenyl)acetonitrile;Benzeneacetonitrile, 3-methoxy-4-(phenylmethoxy)-;4-Benzyloxy-3-methoxybenzyl cyanide, 2-(Benzyloxy)-5-(cyanomethyl)anisole

CBNumber:: CB6367314

Molecular Formula:: C16H15NO2

Molecular Weight:: 253.3

MDL Number:: MFCD00016394

MOL File:: 1700-29-4.mol

MSDS File:: SDS

Last updated:2026-05-28 02:51:13

Product description	Number	Pack Size	Price
4-(Benzyloxy)-3-methoxyphenylacetonitrile 98%	OR7895	250mg	$21
4-(Benzyloxy)-3-methoxyphenylacetonitrile 98%	OR7895	250mg	$21
2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	B58657	250mg	$70
2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	B58657	1g	$77
2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	B58657	5g	$80
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4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE Properties

Melting point	68-70°C
Boiling point	195°C 1mm
Density	1.129±0.06 g/cm3(Predicted)
Flash point	195°C/1mm
storage temp.	Sealed in dry,Room Temperature
BRN	2702492
CAS DataBase Reference	1700-29-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P264-P270-P301+P310a-P321-P405-P501a

Hazard Codes

Risk Statements

Safety Statements

22-36/37

RIDADR

3439

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

2926907090

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
3		0

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR7895	4-(Benzyloxy)-3-methoxyphenylacetonitrile 98%	1700-29-4	250mg	$21	2026-06-04	Buy
Apolloscientific	OR7895	4-(Benzyloxy)-3-methoxyphenylacetonitrile 98%	1700-29-4	250mg	$21	2026-06-04	Buy
Synthonix	B58657	2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	1700-29-4	250mg	$70	2026-05-06	Buy
Synthonix	B58657	2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	1700-29-4	1g	$77	2026-05-06	Buy
Synthonix	B58657	2-(4-(Benzyloxy)-3-methoxyphenyl)acetonitrile 98%	1700-29-4	5g	$80	2026-05-06	Buy

Product number	Packaging	Price	Buy
OR7895	250mg	$21	Buy
OR7895	250mg	$21	Buy
B58657	250mg	$70	Buy
B58657	1g	$77	Buy
B58657	5g	$80	Buy

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE Chemical Properties,Uses,Production

Synthesis

4468-59-1

100-39-0

1700-29-4

4-Phenylmethoxy-3-methoxyphenylacetonitrile was prepared by reaction of 4-hydroxy-3-methoxyphenylacetonitrile (1.08 g, 6.60 mmol, 1.0 eq.) and benzyl bromide (1.24 g, 7.26 mmol, 1.1 eq.) in acetone (14 mL) according to the modified method of Imbri et al. First, K2CO3 (1.10 g, 7.92 mmol, 1.2 eq.) was added to the acetone solution of 4-hydroxy-3-methoxyphenylacetonitrile and the suspension was stirred for 10 min. Subsequently, benzyl bromide was added slowly dropwise via syringe. The reaction mixture was heated to reflux for 4 hours. Upon completion of the reaction, the suspension was separated by filtration and the precipitated solid was washed with acetone (10 mL). The filtrate was concentrated under reduced pressure and diluted with dichloromethane (DCM, 50 mL). The organic layer was washed sequentially with 2N NaOH (30 mL) and brine (30 mL) and then dried with Na2SO4. Finally, the solvent was removed by vacuum to afford the target product, 4-phenylmethoxy-3-methoxyphenylacetonitrile, as a yellow solid (1.67 g, 6.59 mmol, quantitative yield). The thin layer chromatography (TLC) Rf value of the product was 0.43 (cyclohexane/ethyl acetate, 2:1). The melting point was 65-66 °C. Nuclear magnetic resonance hydrogen (1H NMR, 400 MHz, CDCl3) and carbon (13C NMR, 100.6 MHz, CDCl3) data were consistent with the literature reports, confirming the structure of the product.

References

[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 22, p. 6137 - 6148
[2] Chemistry - A European Journal, 2013, vol. 19, # 45, p. 15080 - 15083

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE synthesis

Synthesis of 4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE from 4-HYDROXY-3-METHOXYPHENYLACETONITRILE and Benzyl bromide

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE Preparation Products And Raw materials

Raw materials

4-HYDROXY-3-METHOXYPHENYLACETONITRILE Vanillyl alcohol 4-BENZYLOXY-3-METHOXYBENZYL ALCOHOL 1-(benzyloxy)-4-(broMoMethyl)-2-Methoxybenzene 1-(benzyloxy)-4-(chloromethyl)-2-methoxybenzene

TETRAETHYLAMMONIUM CYANIDE POTASSIUM CYANIDE Benzyl chloride Sodium cyanide 4-BENZYLOXY-3-METHOXYBENZALDEHYDE

Vanillin Benzyl bromide

1of3

Preparation Products

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE Suppliers

Global( 92)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5973	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58

Supplier	Advantage
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Aromsyn Co., Ltd.	58

View Lastest Price from 4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	2-(4-(benzyloxy)-3-methoxyphenyl) acetonitrile 1700-29-4	$1.00	1KG	98%	200kg	Career Henan Chemical Co

2-(4-(benzyloxy)-3-methoxyphenyl) acetonitrile
1700-29-4
$1.00
98%
Career Henan Chemical Co

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE Spectrum

4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE(1700-29-4)MS 4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE(1700-29-4)IR1 4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE(1700-29-4)IR2

1700-29-4(4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE)Related Search:

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4-BENZYLOXY-3-METHOXYPHENYLACETONITRILE 4-Hydroxybenzyl cyanide 4-HYDROXY-3-METHOXYPHENYLACETONITRILE 4-Benzyloxyphenylacetonitrile (3,4-Dimethoxyphenyl)acetonitrile

3,4-DIBENZYLOXYPHENYLACETONITRILE 4-ETHOXYPHENYLACETONITRILE 2-Benzyloxyphenol M-HYDROXY BENZYL CYANIDE