D-Aspartic acid
- CAS No.
- 1783-96-6
- Chemical Name:
- D-Aspartic acid
- Synonyms
- D-ASP;D-(-)-ASPARTIC ACID;H-D-ASP-OH;(R)-2-AMINOSUCCINIC ACID;Aspartic acid D-form;d-aspartic;H-D-Asp;D-Asp-OH;NSC 97922;xuyicaoyou
- CBNumber:
- CB6373566
- Molecular Formula:
- C4H7NO4
- Molecular Weight:
- 133.1
- MDL Number:
- MFCD00063081
- MOL File:
- 1783-96-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| D-Aspartic acid ReagentPlus , 99% | 219096 | 25g | $186 |
| D-Aspartic acid ReagentPlus , 99% | 219096 | 100g | $461 |
| D-Aspartic Acid >98.0%(T) | A0545 | 25g | $138 |
| D-Aspartic Acid ≥95% | 33494 | 10g | $36 |
| D-Aspartic Acid ≥95% | 33494 | 25g | $62 |
| More product size | |||
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 245.59°C (rough estimate) |
| alpha | -25.8 º (c=5, 5N HCl) |
| Density | 1.66 |
| refractive index | -25 ° (C=8, 50% HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Sparingly) |
| pka | pK1: 1.89(0);pK2: 3.65;pK3: 9.60 (25°C) |
| form | Crystalline Powder |
| color | White to off-white |
| optical activity | [α]20/D 24°, c = 2.3 in 6 M HCl |
| Water Solubility | SOLUBLE |
| Merck | 14,840 |
| BRN | 1723529 |
| InChI | 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1 |
| InChIKey | CKLJMWTZIZZHCS-UWTATZPHSA-N |
| SMILES | N[C@H](CC(O)=O)C(O)=O |
| LogP | -1.075 (est) |
| CAS DataBase Reference | 1783-96-6(CAS DataBase Reference) |
| FDA UNII | 4SR0Q8YD1X |
| NIST Chemistry Reference | D-aspartic acid(1783-96-6) |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CI9097500 | |||||||||
| HS Code | 29224995 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
D-Aspartic acid price More Price(133)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 219096 | D-Aspartic acid ReagentPlus , 99% | 1783-96-6 | 25g | $186 | 2026-04-30 | Buy |
| Sigma-Aldrich | 219096 | D-Aspartic acid ReagentPlus , 99% | 1783-96-6 | 100g | $461 | 2026-04-30 | Buy |
| TCI Chemical | A0545 | D-Aspartic Acid >98.0%(T) | 1783-96-6 | 25g | $138 | 2026-04-30 | Buy |
| Cayman Chemical | 33494 | D-Aspartic Acid ≥95% | 1783-96-6 | 10g | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 33494 | D-Aspartic Acid ≥95% | 1783-96-6 | 25g | $62 | 2026-04-30 | Buy |
D-Aspartic acid Chemical Properties,Uses,Production
Chemical Properties
White or almost white crystalline powder
Uses
D-Aspartic acid modulates melatonin synthesis in the pineal gland.
Uses
A non-essential amino acid found in food sources and dietary supplements. D-Aspartic acid's conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms.
Definition
ChEBI: The D-enantiomer of aspartic acid.
reaction suitability
reaction type: solution phase peptide synthesis
Biological Activity
Endogenous NMDA receptor agonist with similar activity to the L-isomer (L-Aminosuccinic acid ). Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
Synthesis
6384-18-5
1783-96-6
In a reaction vessel, 4.85 g (0.03 mol) of dimethyl (S)-2-aminosuccinate was added to 50 mL of 6 M potassium hydroxide solution and the hydrolysis reaction was carried out by heating and refluxing for 3 hrs. Upon completion of the reaction, the pH of the reaction solution was adjusted to 6.5 with 6 N hydrochloric acid.The reaction solution was purified by passing it through a regenerated cation exchange resin column and the effluent with pH=4 was collected. The collected effluent was concentrated under reduced pressure to one-fifth of the original volume and then precipitated by adding 95% methanol. The precipitate was collected by filtration and dried to give 3.3 g of D-aspartic acid in 82.5% yield.
storage
Room temperature
References
[1] Patent: CN105503628, 2016, A. Location in patent: Paragraph 0026
D-Aspartic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong Provichem Biotech Co., Ltd. | +8617505220108 | sales@provichem.cn | China | 34 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5983 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 +86-18829239519 | sales06@tgybio.com | China | 898 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Shandong Xuhuang New material CoLTD | +86-15095020839 +86-17660422208 | China | 726 | 58 | |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
View Lastest Price from D-Aspartic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | D-Aspartic acid
1783-96-6
|
1kg | 99%min AJI | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-06-03 | D-Aspartic acid
1783-96-6
|
$10.00 | 1kg | 98.5%-101.0% | 20 tons | Nantong Provichem Biotech Co., Ltd. | |
 |
2026-05-28 | D-Aspartic acid
1783-96-6
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- D-Aspartic acid
1783-96-6
- 99%min AJI
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- D-Aspartic acid
1783-96-6
- $10.00
- 98.5%-101.0%
- Nantong Provichem Biotech Co., Ltd.
-
- D-Aspartic acid
1783-96-6
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
