METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE
- CAS No.
- 52867-42-2
- Chemical Name:
- METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE
- Synonyms
- Methyl 3-Hydroxy-1-Methyl-1H-Pyrazole-5-Carboxylate;Methyl 3-hydroxy-1-Methylpyrazole;METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYL;methyl 2-methyl-5-oxo-1H-pyrazole-3-carboxylate;METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE;Methyl 3-hydroxy-1-Methyl-1H-pyrazole-4-carboxylate;Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate;5-hydroxy-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester;Methyl 3-Hydroxy-1-Methyl-1H-Pyrazole-5-Carboxylate(WXC00843);2,5-Dihydro-2-methyl-5-oxo-1H-pyrazole-3-carboxylic acid methyl ester
- CBNumber:
- CB6451242
- Molecular Formula:
- C6H8N2O3
- Molecular Weight:
- 156.14
- MDL Number:
- MFCD00459835
- MOL File:
- 52867-42-2.mol
| Product description | Number | Pack Size | Price |
| Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 121971 | 1.00g | $46 |
| Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 121971 | 5.00g | $162 |
| Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 121971 | 25.00g | $711 |
| Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 97% | M43251 | 100mg | $18 |
| Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 97% | M43251 | 250mg | $24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405 |
METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 121971 | Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 52867-42-2 | 1.00g | $46 | 2026-05-18 | Buy |
| Matrix Scientific | 121971 | Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 52867-42-2 | 5.00g | $162 | 2026-05-18 | Buy |
| Matrix Scientific | 121971 | Methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate | 52867-42-2 | 25.00g | $711 | 2026-05-18 | Buy |
| Synthonix | M43251 | Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 97% | 52867-42-2 | 100mg | $18 | 2026-05-06 | Buy |
| Synthonix | M43251 | Methyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate 97% | 52867-42-2 | 250mg | $24 | 2026-05-06 | Buy |
METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
302-15-8
762-42-5
52867-42-2
Step I: Synthesis of methyl 3-hydroxy-1-methyl-1H-pyrazole-5-carboxylate (3_41_2) Triethylamine (66 mL, 474.4 mmol) was added to a mixed solution of methylhydrazine sulfate (30.4 g, 211 mmol) in water (150 mL) and methanol (300 mL). The reaction mixture was stirred at room temperature for 0.5 h. Dimethyl butynedioate (30 g, 211 mmol) was subsequently added. The reaction system was warmed up to 70 °C with continuous stirring for 18 hours. After completion of the reaction, the mixture was allowed to stand at room temperature for two days, the precipitated solid was collected by filtration and dried to give 12 g of the target product. The filtrate was concentrated, cooled in an ice bath and filtered again to collect the solids and dried to give an additional 5 g of the target product 3_41_2 (total 17 g, 52% yield) as a yellow solid. NMR (400 MHz, DMSO-d6): δ = 3.79 (s, 3H), 3.88 (s, 3H), 6.01 (s, 1H), 10.05 (s, 1H).
References
[1] Patent: WO2013/110643, 2013, A1. Location in patent: Paragraph 00351; 00352
[2] Patent: US2018/170909, 2018, A1. Location in patent: Paragraph 1891; 1892
[3] Patent: WO2015/50989, 2015, A2. Location in patent: Paragraph 00299; 00300
METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
| Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | sales@tihondan.com | China | 3767 | 58 |
View Lastest Price from METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-11 | METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE
52867-42-2
|
1kg | 97% | 1000kg | Henan Aochuang Chemical Co.,Ltd. |
-
- METHYL 3-HYDROXY-1-METHYLPYRAZOLE-5-CARBOXYLATE
52867-42-2
- 97%
- Henan Aochuang Chemical Co.,Ltd.
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