1,2,2,6,6-Pentamethyl-4-piperidinol
- CAS No.
- 2403-89-6
- Chemical Name:
- 1,2,2,6,6-Pentamethyl-4-piperidinol
- Synonyms
- Pentamethylpiperidinol;1,2,2,6,6-Pentamethylpiperidin-4-ol;HOPEMP;NSC 364075;METHYL-TAA-OL;Pentamethylpyridinol;1,2,2,6,6-Pentamethy;5-MethylpiperidineAlcohol;1,2,2,6,6-Pentamethyl-4-piperi;N-Methyltriacetoneaminoalcohol
- CBNumber:
- CB6457693
- Molecular Formula:
- C10H21NO
- Molecular Weight:
- 171.28
- MDL Number:
- MFCD00191220
- MOL File:
- 2403-89-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine >98.0%(GC) | H1068 | 500g | $167 |
| 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine >98.0%(GC) | H1068 | 25g | $23 |
| 1,2,2,6,6-Pentamethyl-4-piperidinol | 158679 | 10g | $403 |
| 1,2,2,6,6-Pentamethyl-4-piperidinol 99% | OR929421 | 100g | $26 |
| 1,2,2,6,6-Pentamethyl-4-piperidinol 99% | OR929421 | 500g | $56 |
| More product size | |||
| Melting point | 72-76 °C |
|---|---|
| Boiling point | 238 °C |
| Density | 0.967 |
| vapor pressure | 0.845Pa at 25℃ |
| refractive index | 1.4621 (estimate) |
| Flash point | 118 °C |
| storage temp. | Sealed in dry,Room Temperature |
| form | Flakes |
| pka | 14.93±0.60(Predicted) |
| color | Light yellow |
| Water Solubility | 4.8 g/100 mL (20 ºc) |
| BRN | 1498 |
| InChI | 1S/C10H21NO/c1-9(2)6-8(12)7-10(3,4)11(9)5/h8,12H,6-7H2,1-5H3 |
| InChIKey | NWHNXXMYEICZAT-UHFFFAOYSA-N |
| SMILES | CN1C(C)(C)CC(O)CC1(C)C |
| LogP | 1.15 at 25℃ |
| CAS DataBase Reference | 2403-89-6(CAS DataBase Reference) |
| FDA UNII | LR520BAM5V |
| EPA Substance Registry System | 4-Piperidinol, 1,2,2,6,6-pentamethyl- (2403-89-6) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H317-H411 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xi,C,N,Xn | |||||||||
| Risk Statements | 43-34-22-51/53 | |||||||||
| Safety Statements | 36/37-45-36/37/39-26-61 | |||||||||
| RIDADR | UN3261 - class 8 - PG 1 - EHS - Corrosive solid, acidic, organic, n.o.s., HI: all | |||||||||
| WGK Germany | 2 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 Skin Corr. 1A Skin Sens. 1 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
1,2,2,6,6-Pentamethyl-4-piperidinol price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1068 | 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine >98.0%(GC) | 2403-89-6 | 500g | $167 | 2026-04-30 | Buy |
| TCI Chemical | H1068 | 4-Hydroxy-1,2,2,6,6-pentamethylpiperidine >98.0%(GC) | 2403-89-6 | 25g | $23 | 2026-04-30 | Buy |
| Usbiological | 158679 | 1,2,2,6,6-Pentamethyl-4-piperidinol | 2403-89-6 | 10g | $403 | 2026-06-03 | Buy |
| Apolloscientific | OR929421 | 1,2,2,6,6-Pentamethyl-4-piperidinol 99% | 2403-89-6 | 100g | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR929421 | 1,2,2,6,6-Pentamethyl-4-piperidinol 99% | 2403-89-6 | 500g | $56 | 2026-06-04 | Buy |
1,2,2,6,6-Pentamethyl-4-piperidinol Chemical Properties,Uses,Production
Chemical Properties
LIGHT YELLOW FLAKES
Uses
Reactant for:
Synthesis of photostable blue emitting naphthalimides
Synthesis of blue fluorescent naphthalimide pH chemosensors
Synthesis of crowded piperidines with intramolecularly hydrogen-bonded nitrogen
Synthesis of spiropyrans and spirooxazines
Amine photoredox reactions
Uses
1,2,2,6,6-Pentamethyl-4-piperidinol is used in the synthesis of PDGFR kinase inhibitors. Also, it can be applied to the preparation of a new diol-functionalized amine light stabilizer.
Uses
Reactant for: Synthesis of photostable blue emitting naphthalimides1 Synthesis of blue fluorescent naphthalimide pH chemosensors2 Synthesis of crowded piperidines with intramolecularly hydrogen-bonded nitrogen3 Synthesis of spiropyrans and spirooxazines4 Amine photoredox reactions5
Flammability and Explosibility
Non flammable
Synthesis
1,2,2,6,6-pentamethylpiperidinol was synthesized by reductive methylation reaction using 2,2,6,6-tetramethylpiperidinol, paraformaldehyde and formic acid as the raw materials and water as the solvent, and the structure of the product was characterized by nuclear magnetic resonance (NMR) hydrogen spectroscopy, carbon spectroscopy and infrared spectroscopy. The results of one-way and orthogonal experiments showed that the molar ratio of raw materials had the greatest influence on the reductive methylation reaction, followed by the reaction temperature and finally the reaction time. The suitable conditions for this reductive methylation reaction were: n (tetramethylpiperidinol): n (paraformaldehyde): n (formic acid) = 1:1.05:1.05, reaction temperature of 80 C, reaction time of 2.5 h, and the solvent water could be applied three times. Under this optimized condition, the average yield of pentamethylpiperidinol was 97.9% and the purity was 99.6%.
Toxics Screening Level
The initial threshold screening level (ITSL) for 1,2,2,6,6-pentamethyl-4-piperidinol is 0.1 μg/m3 based on annual averaging time.
1,2,2,6,6-Pentamethyl-4-piperidinol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2998 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
View Lastest Price from 1,2,2,6,6-Pentamethyl-4-piperidinol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
|
1kg | 99%min | 20tons | HANGZHOU HAILAN CHEMICAL CO.,LTD. | ||
 |
2026-07-24 | 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
|
$10.00 | 1kg | 99% | 20tons | Nantong Provichem Biotech Co., Ltd. | |
 |
2026-07-02 | 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
|
$2.20-8.80 | 1kg | 99%min | 1000kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
- $0.00
- 99%min
- HANGZHOU HAILAN CHEMICAL CO.,LTD.
-
- 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
- $10.00
- 99%
- Nantong Provichem Biotech Co., Ltd.
-
- 1,2,2,6,6-Pentamethyl-4-piperidinol
2403-89-6
- $2.20-8.80
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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